Hydrochloric Acid

Hydrochloric Acid

SCHEMBL2019274

C=CC(=O)OC(C)CC(C)(C)N.Cl

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.40
ALDH1A1 P00352 4/20 0.32
TP53 P04637 3/20 0.32
HIF1A Q16665 3/20 0.32
CYP3A4 P08684 2/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3764879 0.98 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
Bromide SCHEMBL26661212 0.96 TSHR (0.40) TSHRALDH1A1TP53HIF1ACYP3A4
Sulfuric Acid SCHEMBL28894458 0.92 TSHR (0.37) TSHR
SCHEMBL28402795 0.88 TSHR (0.34) TSHR
SCHEMBL26100094 0.85 TSHR (0.33) TSHR
SCHEMBL23494088 0.83 TSHR (0.44) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL4655027 0.81 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL4399493 0.81 TSHR (0.39) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL10611134 0.80 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8619029 0.80 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111050903-B Chromatographic packing material for separating and/or detecting methylated DNA 积水医疗株式会社 2023-02-28 CN disclosed
CN-115298110-A Cover tape for packaging electronic component and package 大日本印刷株式会社 2022-11-04 CN disclosed
CN-114349901-A Preparation method of flocculant 常州市振邦化工制造有限公司 2022-04-15 CN disclosed
CN-106062215-B Method for determining prognosis of renal cell carcinoma 国立研究开发法人国立癌研究中心 2020-09-22 CN disclosed
CN-111057752-A Application of ion exchange chromatography and application of PCR (polymerase chain reaction) primer 国立研究开发法人国立癌研究中心 2020-04-24 CN disclosed
CN-111050903-A Chromatographic packing material for separating and/or detecting methylated DNA 积水医疗株式会社 2020-04-21 CN disclosed
US-10550426-B2 Method for detecting methylated DNA SEKISUI MEDICAL CO., LTD. (JP) 2020-02-04 US disclosed
EP-2966179-B1 METHOD FOR DETECTING METHYLATED DNA SEKISUI MEDICAL CO LTD (JP) 2019-05-08 EP disclosed
US-9777193-B2 Thermosensitive adhesive label and labeled container with the same YUPO CORPORATION (JP) 2017-10-03 US disclosed
US-20160138097-A1 METHOD FOR DETECTING METHYLATED DNA SEKISUI MEDICAL CO., LTD. (JP) 2016-05-19 US disclosed
EP-2348084-B1 Thermosensitive adhesive label and labeled container with same YUPO CORP (JP) 2012-10-03 EP disclosed
US-8257806-B2 Surrounding label and article bearing the label YUPO CORPORATION (JP) 2012-09-04 US disclosed
EP-2348084-A1 Thermosensitive adhesive label and labeled container with same Yupo Corporation (JP) 2011-07-27 EP disclosed
US-7981503-B2 Good liquid absorbability with good seepage resistance; , dries within a short period of time and attains good adhesiveness when stuck to objects with a water-base adhesive YUPO CORPORATION (JP) 2011-07-19 US disclosed
US-20110159220-A1 THERMOSENSITIVE ADHESIVE LABEL AND LABELED CONTAINER WITH THE SAME YUPO CORPORATION (JP) 2011-06-30 US disclosed
US-20110159218-A1 THERMOSENSITIVE ADHESIVE LABEL AND LABELED CONTAINER WITH SAME YUPO CORPORATION (JP) 2011-06-30 US disclosed
US-20090169780-A1 SURROUNDING LABEL AND ARTICLE BEARING THE LABEL YUPO CORPORATION (JP) 2009-07-02 US disclosed
EP-1967458-A1 SURROUNDING LABEL AND ARTICLE BEARING THE LABEL Yupo Corporation (JP) 2008-09-10 EP disclosed
US-20050186371-A1 Stretched resin film and label comprising the same YUPO CORPORATION (JP) 2005-08-25 US disclosed
EP-1553126-A1 STRETCHED RESIN FILM AND LABEL COMPRISING THE SAME Yupo Corporation (JP) 2005-07-13 EP disclosed