SCHEMBL2052901

SCHEMBL2052901

CCOC(=O)c1ccn[nH]1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
JMJD6 Q6NYC1 1/20 0.52
HCAR2 Q8TDS4 1/20 0.52
PKM P14618 1/20 0.50
KMT2A Q03164 3/20 0.47
ALDH1A1 P00352 3/20 0.47
MEN1 O00255 2/20 0.47
NAMPT P43490 1/20 0.47
ALPL P05186 1/20 0.47
CYP1A2 P05177 1/20 0.46
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
MAPT P10636 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HPGDS O60760 1/20 0.46
TSHR P16473 1/20 0.46
PDE4D Q08499 1/20 0.44
KDM4E B2RXH2 3/20 0.44
HPGD P15428 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20488641 0.86 ALDH1A1 (0.49) JMJD6HCAR2PKMALDH1A1RAB9A
SCHEMBL30292550 0.79 HCAR2 (0.48) JMJD6HCAR2PKMKMT2AMEN1
SCHEMBL560682 0.79
SCHEMBL29553253 0.78 HCAR2 (0.44) JMJD6HCAR2PKMKMT2AMEN1
SCHEMBL22372270 0.78 PHLPP2 (0.49) HCAR2ALDH1A1CYP1A2RAB9AMAPT
SCHEMBL1623326 0.77 ALDH1A1 (0.51) JMJD6PKMKMT2AALDH1A1MEN1
SCHEMBL13734044 0.77 JMJD6 (0.62) JMJD6KMT2AALDH1A1ALPLRAB9A
SCHEMBL23830167 0.74 HCAR2 (0.52) HCAR2PKMKMT2AMEN1NAMPT
SCHEMBL7165649 0.74 HCAR2 (0.52) HCAR2PKMKMT2AALDH1A1MEN1
SCHEMBL1160497 0.74 LMNA (0.55) KMT2AALDH1A1MEN1CYP1A2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132127-A1 NOVEL SPIRO COMPOUND MITSUBISHI TANABE PHARMA CORPORATION (JP) 2026-05-14 US disclosed
EP-4741392-A1 1H-PYRAZOLO[4,3-C]PYRIDINE COMPOUND, AND COMPOSITION THEREOF AND USE THEREOF Shenzhen TargetRx Co., Ltd. (CN) 2026-05-13 EP disclosed
US-20260109692-A1 KCNT1 INHIBITORS AND METHODS OF USE UCB Biopharma SRL (BE) 2026-04-23 US disclosed
EP-4720678-A1 SURVIVIN AS A BIOMARKER FOR PREDICTING THE RESPONSIVENESS OF CANCER TREATMENT Boehringer Ingelheim International GmbH (DE) 2026-04-08 EP disclosed
US-12570612-B2 Substituted nitrogen heterocyclic compound and anesthetic effect thereof CHENGDU MFS PHARMA. CO., LTD. (CN) 2026-03-10 US disclosed
US-12570675-B2 Boronic acid compounds LG CHEM, LTD. (KR) 2026-03-10 US disclosed
US-12565494-B2 Inhibitors of human respiratory syncytial virus and metapneumovirus MERCK SHARP & DOHME LLC 2026-03-03 US disclosed
US-12545680-B2 Substituted oxaspiro[4.5]decanes as mor receptor agonists SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2026-02-10 US disclosed
US-20260000781-A1 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF CIDARA THERAPEUTICS INC (US) 2026-01-01 US disclosed
US-20250388595-A1 MODULATORS OF EUKARYOTIC INITIATION FACTOR 2B, COMPOSITIONS AND METHODS DENALI THERAPEUTICS INC (US) 2025-12-25 US disclosed
US-20120149691-A1 Pyrrolo [1,2-b] Pyridazine Derivatives as Janus Kinase Inhibitors BIOCRYST PHARMACEUTICALS, INC. (US) 2012-06-14 US disclosed
US-8198275-B2 Adamantyl diamide derivatives and uses of same H. LUNDBECK A/S (DK) 2012-06-12 US disclosed
US-20110178063-A1 BENZPYRAZOL DERIVATIVES AS INHIBITORS OF PI3 KINASES GLAXO GROUP LIMITED (GB) 2011-07-21 US disclosed
US-20110178086-A1 ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME H. LUNDBECK A/S (DK) 2011-07-21 US disclosed
WO-2011079076-A1 SUBSTITUTED N-(1H-INDAZOL-4-YL)IMIDAZO[1, 2-A]PYRIDINE-3- CARBOXAMIDE COMPOUNDS AS CFMS INHIBITORS ARRAY BIOPHARMA INC. (US) 2011-06-30 WO disclosed
US-7947680-B2 Adamantyl diamide derivatives and uses of same H. LUNDBECK A/S 2011-05-24 US disclosed
WO-2011014817-A1 PYRROLO [1, 2-B] PYRIDAZINE DERIVATIVES AS JANUS KINASE INHIBITORS BIOCRYST PHARMACEUTICALS, INC. (US) 2011-02-03 WO disclosed
US-20100022546-A1 ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME H. LUNDBECK A/S (DK) 2010-01-28 US disclosed
US-20100022546-A1 ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME H. LUNDBECK A/S (DK) 2010-01-28 US disclosed
US-7157464-B2 Substituted piperazines CHEMOCENTRYX, INC. (US) 2007-01-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149691-A1 Pyrrolo [1,2-b] Pyridazine Derivatives as Janus Kinase Inhibitors JAK1, JAK2, JAK3 JMJD6 675/4885HCAR2 2894/4885PKM 484/4885
US-20110178063-A1 BENZPYRAZOL DERIVATIVES AS INHIBITORS OF PI3 KINASES PIK3CA, PIK3CD, PI4KA JMJD6 3160/4885HCAR2 4439/4885PKM 486/4885
US-12570675-B2 Boronic acid compounds PSMB6, PSMB3, PSMB2 JMJD6 1226/4885HCAR2 2042/4885PKM 4072/4885
US-12545680-B2 Substituted oxaspiro[4.5]decanes as mor receptor agonists OPRM1, OGFR, OPRL1 JMJD6 2362/4885HCAR2 79/4885PKM 4574/4885
US-20100022546-A1 ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME QDPR, ADM2, PDE3B JMJD6 610/4885HCAR2 1048/4885PKM 3889/4885
US-20110178086-A1 ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME QDPR, PDE3B, ADM2 JMJD6 650/4885HCAR2 998/4885PKM 3876/4885
US-20250388595-A1 MODULATORS OF EUKARYOTIC INITIATION FACTOR 2B, COMPOSITIONS AND METHODS EIF2B1, EIF4EBP1, EIF2B3 JMJD6 2767/4885HCAR2 4122/4885PKM 3604/4885
US-20260132127-A1 NOVEL SPIRO COMPOUND TRHR, NR3C2, THRB JMJD6 3214/4885HCAR2 442/4885PKM 2717/4885
US-12570612-B2 Substituted nitrogen heterocyclic compound and anesthetic effect thereof CNR1, SCN8A, KCNH1 JMJD6 941/4885HCAR2 178/4885PKM 526/4885
US-12565494-B2 Inhibitors of human respiratory syncytial virus and metapneumovirus NHERF1, ZC3HAV1, SARS1 JMJD6 1944/4885HCAR2 2913/4885PKM 4837/4885
US-20260000781-A1 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF FCGR2A, FCGR1A, FCGR3B JMJD6 364/4885HCAR2 1849/4885PKM 4776/4885
US-20260109692-A1 KCNT1 INHIBITORS AND METHODS OF USE KCNT1, KCNJ2, KCNT2 JMJD6 1858/4885HCAR2 1389/4885PKM 673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.