Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG known ✓ | P37231 | 3/20 | 0.61 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.61 |
| ▸ | TOP1 known ✓ | P11387 | 1/20 | 0.61 |
| ▸ | CYP19A1 known ✓ | P11511 | 1/20 | 0.61 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.61 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.61 |
| ▸ | FLT3 known ✓ | P36888 | 1/20 | 0.61 |
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.62 |
| ▸ | TERT | O14746 | 3/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.61 |
| ▸ | PPARD | Q03181 | 3/20 | 0.61 |
| ▸ | PPARA | Q07869 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | FABP4 | P15090 | 2/20 | 0.61 |
| ▸ | FAAH | O00519 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL565988 | 1.00 | EPHX2 (0.62) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL8736540 | 0.98 | EPHX2 (0.64) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL9003892 | 0.98 | EPHX2 (0.64) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL18209378 | 0.98 | EPHX2 (0.64) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL18240158 | 0.98 | EPHX2 (0.64) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL79558 | 0.98 | EPHX2 (0.64) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL8004893 | 0.98 | EPHX2 (0.64) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL8925859 | 0.98 | EPHX2 (0.64) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL5032813 | 0.98 | EPHX2 (0.64) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL18209381 | 0.98 | EPHX2 (0.64) | EPHX2TERTPTPN1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043068-A | RNA vaccine | 阿克丘勒斯治疗公司 | 2024-05-14 | — | — | CN | claimed |
| CN-104955800-B | Hydrogen sulfide scavenger | 艺康美国股份有限公司 | 2018-11-06 | — | — | CN | claimed |
| CN-108348448-A | Oil-in-water type organopolysiloxane emulsion, its manufacturing method, cosmetic material and cosmetics | 道康宁东丽株式会社 | 2018-07-31 | — | — | CN | claimed |
| CN-107530436-A | Methods, compositions and systems for delivering therapeutic and diagnostic agents into cells | 菲泽尔克斯公司 | 2018-01-02 | — | — | CN | claimed |
| CN-106989327-A | A kind of marine LED light fixture | 芜湖市协普机器有限公司 | 2017-07-28 | — | — | CN | claimed |
| CN-104761936-B | Waterborne inorganic heat-insulating and corrosion-resistant coating and preparation method thereof | 泉州三欣新材料科技有限公司 | 2017-04-12 | — | — | CN | claimed |
| CN-110494540-A | Fabric softener composition | PROCTER & GAMBLE | 2019-11-22 | — | — | CN | disclosed |
| CN-109906202-A | Particle complex metal hydroxide, its firing object, its manufacturing method and its resin combination | 协和化学工业株式会社 | 2019-06-18 | — | — | CN | disclosed |
| US-20190167586-A1 | LIPOSOMAL APPARATUS AND MANUFACTURING METHODS | ARBUTUS BIOPHARMA CORP (CA) | 2019-06-06 | — | — | US | disclosed |
| CN-109233784-A | A kind of mixed gas foam fracturing liquid system and its preparation | 中国石油大学(北京) | 2019-01-18 | — | — | CN | disclosed |
| CN-109154145-A | Dissolved air debonding of tissue | GPCP知识产权控股有限责任公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-108779415-A | The composition of organopolysiloxane and cationic surface active agent containing carbamate functional | 瓦克化学股份公司 | 2018-11-09 | — | — | CN | disclosed |
| CN-106536184-B | Laminated body and its manufacturing method | 东洋油墨SC控股株式会社 | 2018-10-02 | — | — | CN | disclosed |
| CN-105567241-A | Soil additive for promoting seed germination and inhibiting evaporation and application method thereof | SOLVAY INVEST CO LTD | 2016-05-11 | — | — | CN | disclosed |
| CN-102939132-B | Sheet material for face mask | KOWA CO.,LTD. (JP) | 2016-01-20 | — | — | CN | disclosed |
| CN-103459576-B | Comprise the Fabrid care composition of front end stablizer | THE PROCTER & GAMBLE CO. (US) | 2015-11-25 | — | — | CN | disclosed |
| CN-105028404-A | Pesticide compositions including polymeric adjuvants | SPECIALTY FERTILIZER PRO LLC | 2015-11-11 | — | — | CN | disclosed |
| CN-103228726-A | Resin composition for injection molding, injection molded foam article, and method for producing injection molded foam article | TOSOH CORP | 2013-07-31 | — | — | CN | disclosed |
| CN-1901796-A | High concentration topical insecticides containing insect growth regulators | HARTZ MOUNTAIN CORP (US) | 2007-01-24 | — | — | CN | disclosed |
| CN-1259162-A | Method for surface pretreatment before formation of photocatalytic hydrophilic film, and detergent and undercoat composition for use in the same | TOTO LTD (JP) | 2000-07-05 | — | — | CN | disclosed |