Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.30 |
| ▸ | LCK known ✓ | P06239 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.30 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27821555 | 1.00 | TDP1 (0.38) | TDP1FFAR3ALDH1A1THRBFNTA | |
| SCHEMBL2352272 | 0.97 | — | — | |
| SCHEMBL127940 | 0.97 | — | — | |
| SCHEMBL4184417 | 0.97 | — | — | |
| Butane SCHEMBL2148303 | 0.92 | FNTA (0.39) | TDP1FFAR3ALDH1A1THRBFNTA | |
| Chloromethane SCHEMBL1802806 | 0.92 | TDP1 (0.36) | TDP1FFAR3ALDH1A1THRBFNTA | |
| Hydrochloric Acid SCHEMBL2357230 | 0.81 | TDP1 (0.40) | TDP1FFAR3ALDH1A1ALOX15LMNA | |
| Hydrochloric Acid SCHEMBL10322255 | 0.80 | FNTA (0.42) | TDP1FFAR3ALDH1A1THRBFNTA | |
| SCHEMBL9445036 | 0.78 | — | — | |
| SCHEMBL1345204 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442746-B2 | Epoxidation of unsaturated cationically stabilized polymer latex | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2008-10-28 | — | — | US | claimed |
| US-20080234438-A1 | EPOXIDATION OF UNSATURATED CATIONICALLY STABILIZED POLYMER LATEX | GOODYEAR TIRE & RUBBER COMPANY, THE | 2008-09-25 | — | — | US | claimed |
| EP-1321489-B1 | Preparation and use of a nanocomposite of elastomer and exfoliated clay platelets formed in situ within an elastomer host and articles of manufacture, including tires, having at least one component comprised thereof | GOODYEAR TIRE & RUBBER (US) | 2008-04-30 | — | — | EP | claimed |
| CN-1923864-A | Preparation technology and application of aminated polymer microspheres | GUANGDONG HONGYE ANTIBODY TECH (CN) | 2007-03-07 | — | — | CN | claimed |
| US-6861462-B2 | Nanocomposite formed in situ within an elastomer and article having component comprised thereof | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-01 | — | — | US | claimed |
| US-20040054059-A1 | Preparation and use of a nanocomposite of elastomer and exfoliated clay platelets formed in situ within an elastomer host and articles of manufacture, including tires, having at least one component comprised thereof | GOODYEAR TIRE & RUBBER COMPANY, THE | 2004-03-18 | — | — | US | claimed |
| EP-1321489-A1 | Preparation and use of a nanocomposite of elastomer and exfoliated clay platelets formed in situ within an elastomer host and articles of manufacture, including tires, having at least one component comprised thereof | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2003-06-25 | — | — | EP | claimed |
| EP-0539729-B1 | Development inhibitor reflector layers | EASTMAN KODAK CO (US) | 1998-07-15 | — | — | EP | claimed |
| US-5441854-A | Photographic image forming process utilizing a barrier layer for diffusible dye containment | EASTMAN KODAK COMPANY (US) | 1995-08-15 | — | — | US | claimed |
| US-5342730-A | With mordant and stripping layers | EASTMAN KODAK COMPANY (US) | 1994-08-30 | — | — | US | claimed |
| US-5322758-A | Integral color diffusion transfer element for large volume development | EASTMAN KODAK COMPANY (US) | 1994-06-21 | — | — | US | claimed |
| EP-0590567-A1 | Integral color diffusion transfer element for large volume development | EASTMAN KODAK COMPANY (US) | 1994-04-06 | — | — | EP | claimed |
| EP-0590565-A1 | Image separation system for large volume development | EASTMAN KODAK COMPANY (US) | 1994-04-06 | — | — | EP | claimed |
| US-5288745-A | Diffusion transfer for color photography; polymeric mordant dye barrier layers | EASTMAN KODAK COMPANY (US) | 1994-02-22 | — | — | US | claimed |
| US-5254441-A | Barrier polymer layer of hydrophobic and ionic hydrophilic unsaturated monomers | EASTMAN KODAK COMPANY (US) | 1993-10-19 | — | — | US | claimed |
| EP-0539729-A1 | Development inhibitor reflector layers | EASTMAN KODAK COMPANY (US) | 1993-05-05 | — | — | EP | claimed |
| US-20240200025-A1 | CELL DISSOCIATING AGENT AND CELL SEPARATION METHOD | NOF CORPORATION (JP) | 2024-06-20 | — | — | US | disclosed |
| EP-4365279-A1 | CELL DISSOCIATING AGENT AND CELL SEPARATION METHOD | NOF Corporation (JP) | 2024-05-08 | — | — | EP | disclosed |
| WO-1992016659-A1 | ELEMENT AND METHOD FOR NUCLEIC ACID AMPLIFICATION AND DETECTION USING ADHERED PROBES | EASTMAN KODAK COMPANY (US) | 1992-10-01 | — | — | WO | disclosed |
| US-4532304-A | Mixing with lower alkyl oxide to convert some halide ions to halohydrins and form free amine site | THE DOW CHEMICAL COMPANY (US) | 1985-07-30 | — | — | US | disclosed |