Butane

Butane

SCHEMBL221072

CCCC.COC(=O)CC(=O)OC

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 2/20 0.58
GAA P10253 2/20 0.58
SI P14410 2/20 0.58
MGAM2 Q2M2H8 2/20 0.58
TSHR P16473 4/20 0.56
HSD17B10 Q99714 2/20 0.50
POLB P06746 1/20 0.45
POLA1 P09884 1/20 0.45
ALDH1A1 P00352 4/20 0.43
CA12 O43570 3/20 0.40
CA14 Q9ULX7 3/20 0.40
KMT2A Q03164 2/20 0.40
TET2 Q6N021 1/20 0.40
MEN1 O00255 1/20 0.40
TP53 P04637 1/20 0.39
LMNA P02545 2/20 0.39
KDM4E B2RXH2 1/20 0.39
RECQL P46063 1/20 0.39
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL53913 0.89
SCHEMBL3441102 0.89 MGAM (0.69) MGAMGAASIMGAM2TSHR
Hydrochloric Acid SCHEMBL5097295 0.86 MGAM (0.65) MGAMGAASIMGAM2TSHR
SCHEMBL4776595 0.86 MGAM (0.65) MGAMGAASIMGAM2TSHR
SCHEMBL9461843 0.86 MGAM (0.65) MGAMGAASIMGAM2TSHR
SCHEMBL11587161 0.86 MGAM (0.65) MGAMGAASIMGAM2TSHR
SCHEMBL708003 0.86 MGAM (0.65) MGAMGAASIMGAM2TSHR
Lithium SCHEMBL11306430 0.86 MGAM (0.65) MGAMGAASIMGAM2TSHR
Bromide SCHEMBL29190335 0.86 MGAM (0.65) MGAMGAASIMGAM2TSHR
SCHEMBL29911291 0.86 MGAM (0.65) MGAMGAASIMGAM2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 299 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12113460-B2 Electrostatic machine system and method of operation C-Motive Technologies, Inc. (US) 2024-10-08 US claimed
CN-117700654-A Copolyester for weather-resistant coating and preparation method and application thereof 中瀚新材料科技有限公司 2024-03-15 CN claimed
CN-114805647-A Catalyst composition for olefin polymerization and application thereof 北京肯佰恩科技发展有限公司 2022-07-29 CN claimed
CN-114605622-A Aliphatic polyester with malonic acid structure and preparation method and application thereof 苏州瀚海新材料有限公司 2022-06-10 CN claimed
CN-111333509-B Apple flavor compound, preparation method thereof and food additive 东莞波顿香料有限公司 2022-06-10 CN claimed
US-20210391810-A1 ELECTROSTATIC MACHINE SYSTEM AND METHOD OF OPERATION C-Motive Technologies, Inc. (US) 2021-12-16 US claimed
EP-3881425-A1 ELECTROSTATIC MACHINE SYSTEM AND METHOD OF OPERATION C-Motive Technologies, Inc. (US) 2021-09-22 EP claimed
CN-112574140-A Preparation method of novel epoxy end-capping agent 天津工业大学 2021-03-30 CN claimed
CN-112225657-A Preparation method of flurbiprofen 北京泰德制药股份有限公司 2021-01-15 CN claimed
CN-111333509-A Apple flavor compound, preparation method thereof and food additive 东莞波顿香料有限公司 2020-06-26 CN claimed
WO-2020101796-A1 ELECTROSTATIC MACHINE SYSTEM AND METHOD OF OPERATION C-Motive Technologies, Inc. (US) 2020-05-22 WO claimed
US-20080182767-A1 Compounds and Lubricating Compositions Containing the Compounds AFTON CHEMICAL CORPORATION 2008-07-31 US claimed
WO-2001072704-A1 AZETIDINONE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND A METHOD FOR PRODUCING 1-β-ALKYL AZETIDINONE USING THE SAME DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2001-10-04 WO claimed
EP-0674233-B1 Recording sheets XEROX CORP (US) 2000-05-24 EP claimed
US-6025487-A Isomerisation process GLAXO WELLCOME SPA (IT) 2000-02-15 US claimed
US-5928765-A Recording sheets XEROX CORPORATION (US) 1999-07-27 US claimed
EP-0871635-A1 ISOMERISATION PROCESS GLAXO WELLCOME S.p.A. (IT) 1998-10-21 EP claimed
WO-1997006174-A1 ISOMERISATION PROCESS GLAXO WELLCOME SPA (IT) 1997-02-20 WO claimed
EP-0674233-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed
EP-4038109-B1 ZIEGLER-NATTA CATALYSTS FOR OLEFIN POLYMERIZATION BOREALIS GMBH (AT) 2025-12-03 EP disclosed
US-12391778-B2 Ziegler-natta catalysts for olefin polymerization BOREALIS AG (AT) 2025-08-19 US disclosed
EP-3730529-B1 BLOCKED ISOCYANATE MITSUI CHEMICALS INC (JP) 2025-03-05 EP disclosed
CN-118909170-A Catalyst system for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2024-11-08 CN disclosed
US-12113460-B2 Electrostatic machine system and method of operation C-Motive Technologies, Inc. (US) 2024-10-08 US disclosed
CN-114805647-B Catalyst composition for olefin polymerization and application thereof 北京肯佰恩科技发展有限公司 2024-03-29 CN disclosed
CN-117700654-A Copolyester for weather-resistant coating and preparation method and application thereof 中瀚新材料科技有限公司 2024-03-15 CN disclosed
CN-117480452-A Photosensitive colored resin composition, cured product, color filter, display device, and method for producing laminate of organic light-emitting element and external light reflection preventing film DNP精细化工股份有限公司 2024-01-30 CN disclosed
US-11884624-B2 Difluorolactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions CAYMAN CHEMICAL COMPANY, INC. (US) 2024-01-30 US disclosed
US-20230340184-A1 WATER-DISPERSIBLE BLOCKED ISOCYANATE, FIBER-TREATING AGENT, WATER REPELLENT, COATING COMPOSITION, AND ADHESIVE MITSUI CHEMICALS, INC. (JP) 2023-10-26 US disclosed
WO-2023190497-A1 ANTIBACTERIAL AGENT 三井化学株式会社 2023-10-05 WO disclosed
EP-4215592-A1 WATER-DISPERSIBLE BLOCKED ISOCYANATE, FIBER-TREATING AGENT, WATER REPELLENT, COATING COMPOSITION, AND ADHESIVE Mitsui Chemicals, Inc. (JP) 2023-07-26 EP disclosed
CN-113912755-B Catalyst composition for olefin polymerization and application thereof 张一锴 2023-06-02 CN disclosed
US-20230104741-A1 Primer Composition for Optical Article, and Laminate TOKUYAMA CORPORATION (JP) 2023-04-06 US disclosed
CN-115806511-A Synthesis method of 5-p-toluenesulfonyl pentyl-2-methyl diethyl malonate 江苏省原子医学研究所 2023-03-17 CN disclosed
CN-115806511-A Synthesis method of 5-p-toluenesulfonyl pentyl-2-methyl diethyl malonate 江苏省原子医学研究所 2023-03-17 CN disclosed
US-20230050318-A1 DIFLUOROLACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS CAYMAN CHEMICAL COMPANY, INC. 2023-02-16 US disclosed
CN-115666539-A Treatment of psoriasis and skin inflammatory diseases 兹杜斯生命科学有限公司 2023-01-31 CN disclosed
US-20220380496-A1 ZIEGLER-NATTA CATALYSTS FOR OLEFIN POLYMERIZATION BOREALIS AG (AT) 2022-12-01 US disclosed
EP-4088927-A1 PRIMER COMPOSITION FOR OPTICAL ARTICLE, AND LAMINATE Tokuyama Corporation (JP) 2022-11-16 EP disclosed
US-20220332718-A1 PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS GENENTECH, INC. (US) 2022-10-20 US disclosed
EP-4038109-A1 ZIEGLER-NATTA CATALYSTS FOR OLEFIN POLYMERIZATION Borealis AG (AT) 2022-08-10 EP disclosed
CN-114805647-A Catalyst composition for olefin polymerization and application thereof 北京肯佰恩科技发展有限公司 2022-07-29 CN disclosed
CN-114605622-A Aliphatic polyester with malonic acid structure and preparation method and application thereof 苏州瀚海新材料有限公司 2022-06-10 CN disclosed
CN-111333509-B Apple flavor compound, preparation method thereof and food additive 东莞波顿香料有限公司 2022-06-10 CN disclosed
US-11345690-B2 Methods of synthesizing a difluorolactam analog CAYMAN CHEMICAL COMPANY, INC. (US) 2022-05-31 US disclosed
WO-2022107418-A1 COATING MATERIAL COMPOSITION 関西ペイント株式会社 2022-05-27 WO disclosed
US-20220127252-A9 METHODS OF SYNTHESIZING A DIFLUOROLACTAM ANALOG CAYMAN CHEMICAL CO INC (US) 2022-04-28 US disclosed
CN-113912755-A Catalyst composition for olefin polymerization and application thereof 张一锴 2022-01-11 CN disclosed
US-20210391810-A1 ELECTROSTATIC MACHINE SYSTEM AND METHOD OF OPERATION C-Motive Technologies, Inc. (US) 2021-12-16 US disclosed
EP-3881425-A1 ELECTROSTATIC MACHINE SYSTEM AND METHOD OF OPERATION C-Motive Technologies, Inc. (US) 2021-09-22 EP disclosed
CN-113273075-A Electrostatic machine system and method of operation C-莫蒂夫技术公司 2021-08-17 CN disclosed
CN-109694420-B Catalyst system for olefin polymerization, prepolymerized catalyst and olefin polymerization process 中国石油化工股份有限公司 2021-08-03 CN disclosed
US-11066361-B2 Difluorolactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions CAYMAN CHEMICAL COMPANY, INC. (US) 2021-07-20 US disclosed
US-11034698-B2 Pyrazolo[ 1,5a]pyrimidine derivatives as IRAK4 modulators GENENTECH, INC. (US) 2021-06-15 US disclosed
US-11021617-B2 Polymers including one or more 1,1-disubstituted alkene compounds and polymer compositions thereof SIRRUS, INC. (US) 2021-06-01 US disclosed
US-10988478-B1 Pyrazolo[1,5a]pyrimidine derivatives as IRAK4 modulators GENENTECH, INC. (US) 2021-04-27 US disclosed
WO-2021064078-A1 ZIEGLER-NATTA CATALYSTS FOR OLEFIN POLYMERIZATION BOREALIS AG (AT) 2021-04-08 WO disclosed
CN-112574140-A Preparation method of novel epoxy end-capping agent 天津工业大学 2021-03-30 CN disclosed
EP-3786199-A1 POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF Sirrus, Inc. (US) 2021-03-03 EP disclosed
CN-112225657-A Preparation method of flurbiprofen 北京泰德制药股份有限公司 2021-01-15 CN disclosed
EP-3191533-B1 POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF SIRRUS INC (US) 2020-11-04 EP disclosed
CN-107802623-B Difluorolactam compositions for EP 4-mediated bone-related diseases and disorders 开曼化学股份有限公司 2020-10-30 CN disclosed
EP-3730529-A1 BLOCKED ISOCYANATE Mitsui Chemicals, Inc. (JP) 2020-10-28 EP disclosed
US-10729810-B2 Methods, systems, and compositions for promoting bone growth CAYMAN CHEMICAL COMPANY, INC (US) 2020-08-04 US disclosed
CN-106748951-B Difluorolactam compounds as EP4 receptor selective agonists for use in the treatment of EP4 mediated diseases and conditions 开曼化学股份有限公司 2020-07-24 CN disclosed
EP-3683267-A1 EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS Sirrus, Inc. (US) 2020-07-22 EP disclosed
EP-3191546-B1 EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS SIRRUS INC (US) 2020-07-22 EP disclosed
US-20200207709-A1 DIFLUOROLACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS CAYMAN CHEMICAL COMPANY, INC. 2020-07-02 US disclosed
CN-111333509-A Apple flavor compound, preparation method thereof and food additive 东莞波顿香料有限公司 2020-06-26 CN disclosed
EP-3176162-B1 DIFLUOROLACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASE AND CONDITIONS CAYMAN CHEMICAL CO INC (US) 2020-05-27 EP disclosed
WO-2020101796-A1 ELECTROSTATIC MACHINE SYSTEM AND METHOD OF OPERATION C-Motive Technologies, Inc. (US) 2020-05-22 WO disclosed
EP-3642204-A1 PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS H. Hoffnabb-La Roche Ag (CH) 2020-04-29 EP disclosed
US-10633566-B2 Polymers containing a 1,1-disubstituted alkene compound SIRRUS, INC. (US) 2020-04-28 US disclosed
US-20200123166-A1 PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS GENENTECH, INC. (US) 2020-04-23 US disclosed
CN-111018704-A Preparation method of diethyl methylmalonate by taking heteropoly acid as catalyst 江西万里药业有限公司 2020-04-17 CN disclosed
EP-2117909-B2 REINFORCING SYSTEM FOR REINFORCING A CAVITY OF A STRUCTURAL ELEMENT SIKA TECH AG (CH) 2020-04-01 EP disclosed
US-10556862-B2 Difluorolactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions CAYMAN CHEMICAL COMPANY, INC. (US) 2020-02-11 US disclosed
US-20190263955-A1 POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF SIRRUS, INC. 2019-08-29 US disclosed
US-20190202816-A1 METHODS OF SYNTHESIZING A DIFLUOROLACTAM ANALOG CAYMAN CHEMICAL CO INC (US) 2019-07-04 US disclosed
US-10308802-B2 Polymers including one or more 1,1-disubstituted alkene compounds and polymer compositions thereof SIRRUS, INC. (US) 2019-06-04 US disclosed
US-20190153272-A1 POLYMERS CONTAINING A 1,1-DISUBSTITUTED ALKENE COMPOUND SIRRUS, INC. 2019-05-23 US disclosed
US-20190144435-A1 DIFLUOROLACTAM COMPOSITIONS FOR EP4-MEDIATED OSTEO RELATED DISEASES AND CONDITIONS MYOMETRICS, LLC (US) 2019-05-16 US disclosed
US-20190135835-A1 MK2 INHIBITORS AND USES THEREOF BRISTOL-MYERS SQUIBB COMPANY 2019-05-09 US disclosed
US-20190092722-A1 DIFLUOROLACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS CAYMAN CHEMICAL COMPANY, INC. 2019-03-28 US disclosed
US-10184073-B2 Emulsion including polymers containing a 1,1-disubstituted alkene compound, adhesives, coatings, and methods thereof SIRRUS, INC. (US) 2019-01-22 US disclosed
WO-2018234345-A1 PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS F. HOFFMANN-LA ROCHE AG (CH) 2018-12-27 WO disclosed
EP-3235817-B1 LACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS CAYMAN CHEMICAL CO INC (US) 2018-12-12 EP disclosed
US-10138256-B2 MK2 inhibitors and uses thereof CELGENE CAR LLC (BM) 2018-11-27 US disclosed
EP-3394066-A2 PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS H. Hoffnabb-La Roche Ag (CH) 2018-10-31 EP disclosed
US-20180298011-A1 PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT GILEAD SCIENCES, INC. 2018-10-18 US disclosed
US-20180298015-A1 PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS GENENTECH, INC. (US) 2018-10-18 US disclosed
US-10081685-B2 Emulson polymers including one or more 1,1-disubstituted alkene compounds, emulson methods, and polymer compositions SIRRUS, INC. (US) 2018-09-25 US disclosed
US-20180170918-A1 METHODS OF SYNTHESIZING A DIFLUOROLACTAM ANALOG CAYMAN CHEMICAL CO INC (US) 2018-06-21 US disclosed
US-9957275-B2 Pyrazolo[1,5-A]pyrimidines for antiviral treatment GILEAD SCIENCES, INC. (US) 2018-05-01 US disclosed
US-9914725-B2 Methods of synthesizing a difluorolactam analog CAYMAN CHEMICAL COMPANY, INC. (US) 2018-03-13 US disclosed
EP-2669270-B1 INDOLE-RELATED COMPOUNDS AS URAT1 INHIBITORS SATO PHARMA (JP) 2018-01-03 EP disclosed
US-20170362244-A1 PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT GILEAD SCIENCES, INC. 2017-12-21 US disclosed
US-9803130-B2 Methods of activating enzyme breakers SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2017-10-31 US disclosed
EP-3235817-A1 LACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS Cayman Chemical Company, Incorporated (US) 2017-10-25 EP disclosed
US-20170275446-A1 POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF NIPPON SHOKUBAI CO., LTD. (JP) 2017-09-28 US disclosed
US-20170260173-A1 DIFLUOROLACTAM COMPOSITIONS FOR EP4-MEDIATED OSTEO RELATED DISEASES AND CONDTIONS MYOMETRICS, LLC (US) 2017-09-14 US disclosed
EP-3191546-A1 EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS Sirrus, Inc. (US) 2017-07-19 EP disclosed
EP-3191533-A1 POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF Sirrus, Inc. (US) 2017-07-19 EP disclosed
US-20170198181-A1 EMULSION INCLUDING POLYMERS CONTAINING A 1,1-DISUBSTITUTED ALKENE COMPOUND, ADHESIVES, COATINGS, AND METHODS THEREOF NIPPON SHOKUBAI CO., LTD. (JP) 2017-07-13 US disclosed
US-9701630-B2 Difluorolactam compositions for EP4-mediated osteo related diseases and conditions CAYMAN CHEMICAL COMPANY, INC. (US) 2017-07-11 US disclosed
US-20170190807-A1 EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS SIRRUS, INC. 2017-07-06 US disclosed
US-20170190708-A1 PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT GILEAD SCIENCES, INC. 2017-07-06 US disclosed
WO-2017108723-A2 PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS F. HOFFMANN-LA ROCHE AG (CH) 2017-06-29 WO disclosed
US-9688627-B2 Lactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions CAYMAN CHEMICAL COMPANY, INC. (US) 2017-06-27 US disclosed
US-9676712-B2 Lactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions CAYMAN CHEMICAL COMPANY, INC. (US) 2017-06-13 US disclosed
EP-3176162-A1 DIFLUOROLACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASE AND CONDITIONS Cayman Chemical Company, Incorporated (US) 2017-06-07 EP disclosed
EP-3175852-A1 DIFLUOROLACTAM COMPOSITIONS FOR EP4-MEDIATED OSTEO RELATED DISEASES AND CONDITIONS Cayman Chemical Company, Incorporated (US) 2017-06-07 EP disclosed
EP-2989098-B1 LACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS CAYMAN CHEMICAL CO INC (US) 2017-05-10 EP disclosed
US-9637564-B2 Emulsion polymers including one or more 1,1-disubstituted alkene compounds, emulsion methods, and polymer compositions SIRRUS, INC. (US) 2017-05-02 US disclosed
US-20170066751-A1 DIFLUOROLACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS CAYMAN CHEMICAL CO INC (US) 2017-03-09 US disclosed
US-20160340306-A1 DIFLUOROLACTAM COMPOSITIONS FOR EP4-MEDIATED OSTEO RELATED DISEASES AND CONDITIONS CAYMAN CHEMICAL COMPANY, INCORPORATED 2016-11-24 US disclosed
US-9487478-B2 Difluorolactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions CAYMAN CHEMICAL COMPANY, INC. (US) 2016-11-08 US disclosed
EP-2874620-B1 DIFLUOROLACTAM COMPOSITIONS FOR EP4-MEDIATED OSTEO RELATED DISEASES AND CONDITIONS CAYMAN CHEMICAL CO INC (US) 2016-10-12 EP disclosed
EP-2875022-B1 DIFLUOROLACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASE AND CONDITIONS CAYMAN CHEMICAL CO INC (US) 2016-10-12 EP disclosed
US-9440919-B2 Difluorolactam compositions for EP4-mediated osteo related diseases and conditions CAYMAN CHEMICAL COMPANY, INC. (US) 2016-09-13 US disclosed
US-20160158413-A1 METHODS, SYSTEMS, AND COMPOSITIONS FOR PROMOTING BONE GROWTH CAYMAN CHEMICAL COMPANY, INC. (US) 2016-06-09 US disclosed
US-9359350-B2 Ring-fused compound SATO PHARMACEUTICAL CO., LTD. (JP) 2016-06-07 US disclosed
EP-3021879-A2 METHODS, SYSTEMS, AND COMPOSITIONS FOR PROMOTING BONE GROWTH Cayman Chemical Company, Incorporated (US) 2016-05-25 EP disclosed
US-20160130275-A1 PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT GILEAD SCIENCES, INC. 2016-05-12 US disclosed
EP-3012258-A1 PYRAZOLO[1,5-A]PYRIMIDINES AND -TRIAZINES AS ANTIVIRAL AGENTS Gilead Sciences, Inc. (US) 2016-04-27 EP disclosed
US-20160096907-A1 EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS SIRRUS, INC. 2016-04-07 US disclosed
WO-2016040261-A1 POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF SIRRUS, INC. (US) 2016-03-17 WO disclosed
WO-2016040012-A1 EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS SIRRUS, INC. (US) 2016-03-17 WO disclosed
US-20160060216-A1 LACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS CAYMAN CHEMICAL COMPANY, INCORPORATED 2016-03-03 US disclosed
US-20160060253-A1 METHODS OF SYNTHESIZING A DIFLUOROLACTAM ANALOG CAYMAN CHEMICAL COMPANY, INC. 2016-03-03 US disclosed
EP-2585467-B1 PYRAZOLO[1,5-A]PYRIMIDINES AND -TRIAZINES AS ANTIVIRAL AGENTS GILEAD SCIENCES INC (US) 2016-03-02 EP disclosed
EP-2989098-A2 LACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS Cayman Chemical Company, Incorporated (US) 2016-03-02 EP disclosed
US-20160031811-A1 LACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS CAYMAN CHEMICAL COMPANY, INCORPORATED 2016-02-04 US disclosed
US-9249265-B1 Emulsion polymers including one or more 1,1-disubstituted alkene compounds, emulsion methods, and polymer compositions SIRRUS, INC. (US) 2016-02-02 US disclosed
US-20160024006-A1 DIFLUOROLACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS CAYMAN CHEMICAL COMPANY, INC. 2016-01-28 US disclosed
EP-2968339-A1 MK2 INHIBITORS AND USES THEREOF Celgene Avilomics Research, Inc. (US) 2016-01-20 EP disclosed
EP-2970234-A2 METHODS OF SYNTHESIZING A DIFLUOROLACTAM ANALOG Cayman Chemical Company, Inc. (US) 2016-01-20 EP disclosed
US-9238039-B2 Pyrazolo[1,5-A]pyrimidines for antiviral treatment GILEAD SCIENCES, INC. (US) 2016-01-19 US disclosed
US-20150376208-A1 MK2 INHIBITORS AND USES THEREOF CELGENE AVILOMICS RESEARCH, INC. (US) 2015-12-31 US disclosed
US-9180116-B2 Difluorolactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions CAYMAN CHEMICAL COMPANY, INC. (US) 2015-11-10 US disclosed
US-20150272947-A1 INHIBITORS OF PROTEIN KINASES ASTRAZENECA AB (SE) 2015-10-01 US disclosed
WO-2015114092-A1 ANTIFOULING COMPOSITION JOTUN A/S (NO) 2015-08-06 WO disclosed
US-20150203490-A1 RING-FUSED COMPOUND SATO PHARMACEUTICAL CO., LTD. (JP) 2015-07-23 US disclosed
US-9067888-B2 Inhibitors of protein kinases ASTRAZENECA AB (SE) 2015-06-30 US disclosed
US-20150174099-A1 DIFLUOROLACTAM COMPOSITIONS FOR EP4-MEDIATED OSTEO RELATED DISEASES AND CONDITIONS CAYMAN CHEMICAL COMPANY, INCORPORATED 2015-06-25 US disclosed
US-20150175538-A1 DIFLUOROLACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS CAYMAN CHEMICAL COMPANY, INC. 2015-06-25 US disclosed
EP-2875022-A1 DIFLUOROLACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASE AND CONDITIONS Cayman Chemical Company, Incorporated (US) 2015-05-27 EP disclosed
EP-2874620-A1 DIFLUOROLACTAM COMPOSITIONS FOR EP4-MEDIATED OSTEO RELATED DISEASES AND CONDITIONS Cayman Chemical Company, Incorporated (US) 2015-05-27 EP disclosed
US-8987473-B2 Ring-fused compound SATO PHARMACEUTICAL CO., LTD. (JP) 2015-03-24 US disclosed
WO-2015009991-A2 METHODS, SYSTEMS, AND COMPOSITIONS FOR PROMOTING BONE GROWTH CAYMAN CHEMICAL COMPANY, INC. (US) 2015-01-22 WO disclosed
WO-2014149164-A1 MK2 INHIBITORS AND USES THEREOF CELGENE AVILOMICS RESEARCH, INC. (US) 2014-09-25 WO disclosed
WO-2014144584-A2 LACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS CAYMAN CHEMICAL COMPANY, INC. (US) 2014-09-18 WO disclosed
WO-2014144610-A1 LACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS CAYMAN CHEMICAL COMPANY, INC. (US) 2014-09-18 WO disclosed
WO-2014144500-A2 METHODS OF SYNTHESIZING A DIFLUOROLACTAM ANALOG CAYMAN CHEMICAL COMPANY, INC. (US) 2014-09-18 WO disclosed
US-8809330-B2 Pyrazolo[1,5-A]pyrimidines for antiviral treatment GILEAD SCIENCES, INC. (US) 2014-08-19 US disclosed
US-8765766-B2 Pyrimidine derivatives which are antagonists of the vitronectin receptor GALAPAGOS NV (BE) 2014-07-01 US disclosed
US-20140154240-A1 PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT GILEAD SCIENCES, INC. 2014-06-05 US disclosed
EP-1788049-B1 THERMOSETTING AQUEOUS COATING COMPOSITION KANSAI PAINT CO LTD (JP) 2014-05-21 EP disclosed
US-20140121136-A1 METHODS OF ACTIVATING ENZYME BREAKERS SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2014-05-01 US disclosed
WO-2014066708-A1 METHODS OF ACTIVATING ENZYME BREAKERS SCHLUMBERGER CANADA LIMITED (CA) 2014-05-01 WO disclosed
US-20140072554-A1 PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT GILEAD SCIENCES, INC. (US) 2014-03-13 US disclosed
WO-2014015247-A1 DIFLUOROLACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASE AND CONDITIONS CAYMAN CHEMICAL COMPANY, INC. (US) 2014-01-23 WO disclosed
WO-2014015246-A1 DIFLUOROLACTAM COMPOSITIONS FOR EP4-MEDIATED OSTEO RELATED DISEASES AND CONDITIONS CAYMAN CHEMICAL COMPANY, INC. (US) 2014-01-23 WO disclosed
US-20140005221-A1 RING-FUSED COMPOUND SATO PHARMACEUTICAL CO., LTD. (JP) 2014-01-02 US disclosed
US-20130345233-A1 INHIBITORS OF PROTEIN KINASES INGENIUM PHARMACEUTICALS GMBH (DE) 2013-12-26 US disclosed
EP-2669270-A1 RING-FUSED COMPOUND Sato Pharmaceutical Co., Ltd. (JP) 2013-12-04 EP disclosed
EP-2638034-A1 SUBSTITUTED HETEROAROMATIC CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS Grünenthal GmbH (DE) 2013-09-18 EP disclosed
US-8518948-B2 Inhibitors of protein kinases INGENIUM PHARMACEUTICALS GMBH (DE) 2013-08-27 US disclosed
US-8486938-B2 Pyrazolo[1,5-a]pyrimidines for antiviral treatment GILEAD SCIENCES, INC. (US) 2013-07-16 US disclosed
EP-2585467-A1 PYRAZOLO [1, 5 -A]PYRIMIDINES AS ANTIVIRAL AGENTS Gilead Sciences, Inc. (US) 2013-05-01 EP disclosed
EP-2545037-A1 INHIBITORS OF PROTEIN KINASES Ingenium Pharmaceuticals GmbH (DE) 2013-01-16 EP disclosed
US-20120178750-A1 Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment MERCK SHARP & DOHME CORP. (US) 2012-07-12 US disclosed
US-8216490-B2 Aqueous primer composition and a process for the application of the same KANSAI PAINT CO., LTD. (JP) 2012-07-10 US disclosed
WO-2012062462-A1 SUBSTITUTED HETEROAROMATIC CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS Grünenthal GmbH (DE) 2012-05-18 WO disclosed
US-20120115903-A1 Substituted Heteroaromatic Carboxamide and Urea Compounds as Vanilloid Receptor Ligands GRUENENTHAL GMBH (DE) 2012-05-10 US disclosed
US-20120115883-A1 PYRIMIDINE DERIVATIVES WHICH ARE ANTAGONISTS OF THE VITRONECTIN RECEPTOR GALAPAGOS SAS 2012-05-10 US disclosed
US-8168649-B2 Niacin receptor agonists, compositions containing such compounds and methods of treatment Merk Sharp & Dohme Corp. (US) 2012-05-01 US disclosed
US-8133896-B2 Pyrimidine derivatives which are antagonist of the vitronectin receptor GALAPAGOS NV (BE) 2012-03-13 US disclosed
US-20120003215-A1 PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT GILEAD SCIENCES, INC. (US) 2012-01-05 US disclosed
WO-2011163518-A1 PYRAZOLO [1, 5 -A] PYRIMIDINES AS ANTIVIRAL AGENTS GILEAD SCIENCES, INC. (US) 2011-12-29 WO disclosed
EP-1268976-B1 VISCOSITY REDUCTION OF VISCOELASTIC SURFACTANT BASED FLUIDS SOFITECH NV (BE) 2011-10-05 EP disclosed
US-20110224225-A1 Inhibitors of protein kinases ASTRAZENECA AB (SE) 2011-09-15 US disclosed
WO-2011110612-A1 INHIBITORS OF PROTEIN KINASES INGENIUM PHARMACEUTICALS GMBH (DE) 2011-09-15 WO disclosed
EP-1901731-B1 NIACIN RECEPTOR AGONISTS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT MERCK SHARP & DOHME (US) 2011-03-02 EP disclosed
US-20110039867-A1 PYRIMIDINE DERIVATIVES WHICH ARE ANTAGONIST OF THE VITRONECTIN RECEPTOR GALAPAGOS SAS 2011-02-17 US disclosed
US-7846932-B2 treatment of retinopathy comprising administering drugs such as tert-butyl 3-[5-ethyl-6-[4-(5,6,7,8-tetrahydro-(1,8)naphthyridin-2-yl)-piperidin-1-yl]-pyrimidin-4-ylamino]-2-(4-methoxy benzoyl)-propionate GALAPAGOS SAS (FR) 2010-12-07 US disclosed
US-7838076-B2 Thermosetting aqueous paint composition KANSAI PAINT CO., LTD. (JP) 2010-11-23 US disclosed
US-7825119-B2 Bone disorders such as osteoporosis, tumors and cardiovascular disorders; 4-(2-carboxy-2-Boc-aminoethylamino)-6-piperidinopyrimidines such as tert-butyl 2-benzyloxycarbonylamino-3-[2,5-dimethoxy-6-(4-[1,8]naphthyridin-2-yl-piperidin-1-yl)pyrimidin-4-ylamino]-propionate GALAPAGOS SAS (FR) 2010-11-02 US disclosed
US-7763621-B2 Vitronectin receptor antagonist derivatives, method for preparing same, use thereof as medicines and pharmaceutical compositions containing same GALAPAGOS SAS (FR) 2010-07-27 US disclosed
US-20100144778-A1 Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment MERCK SHARP & DOHME LLC 2010-06-10 US disclosed
US-20100041675-A1 treatment of retinopathy comprising administering drugs such as tert-butyl 3-[5-ethyl-6-[4-(5,6,7,8-tetrahydro-(1,8)naphthyridin-2-yl)-piperidin-1-yl]-pyrimidin-4-ylamino]-2-(4-methoxy benzoyl)-propionate GALAPAGOS SAS 2010-02-18 US disclosed
EP-1534926-B1 VISCOSITY REDUCTION OF VISCOELASTIC SURFACTANT BASED FLUIDS SCHLUMBERGER SERVICES PETROL (FR) 2009-11-04 EP disclosed
US-7582640-B2 Vitronectin receptor antagonist derivatives, method for preparing same, use thereof as medicines and pharmaceutical compositions containing same GALAPAGOS SAS (FR) 2009-09-01 US disclosed
US-20090149476-A1 Novel vitronectin receptor antagonist derivatives, method for preparing same, use thereof as medicines and pharmaceutical compositions containing same GALAPAGOS SAS 2009-06-11 US disclosed
US-20090130322-A1 Aqueous Primer Composition and a Process for the Application of the Same KANSAI PAINT CO., LTD. (JP) 2009-05-21 US disclosed
EP-1831198-B1 PYRIDINE CARBOXAMIDE DERIVATIVES FOR USE AS ANTICANCER AGENTS ASTRAZENECA AB (SE) 2009-04-08 EP disclosed
US-20080182767-A1 Compounds and Lubricating Compositions Containing the Compounds AFTON CHEMICAL CORPORATION 2008-07-31 US disclosed
EP-1947153-A1 AQUEOUS PRIMER COMPOSITION AND METHOD FOR APPLYING SAME KANSAI PAINT CO., LTD. (JP) 2008-07-23 EP disclosed
US-20080095944-A1 Thermosetting Aqueous Paint Composition KANSAI PAINT CO., LTD. (JP) 2008-04-24 US disclosed
EP-1901731-A1 NIACIN RECEPTOR AGONISTS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT Merck & Co., Inc. (US) 2008-03-26 EP disclosed
US-20080058348-A1 Bone disorders such as osteoporosis, tumors and cardiovascular disorders; 4-(2-carboxy-2-Boc-aminoethylamino)-6-piperidinopyrimidines such as tert-butyl 2-benzyloxycarbonylamino-3-[2,5-dimethoxy-6-(4-[1,8]naphthyridin-2-yl-piperidin-1-yl)pyrimidin-4-ylamino]-propionate PROSKELIA SAS 2008-03-06 US disclosed
US-20070281969-A1 Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment MERCK SHARP & DOHME CORP. 2007-12-06 US disclosed
US-20070259123-A1 Aqueous Primer Composition KANSAI PAINT CO., LTD. (JP) 2007-11-08 US disclosed
US-20070237903-A1 Thermosetting Water-Based Coating Composition and Method of Forming Coating Film KANSAI PAINT CO., LTD (JP) 2007-10-11 US disclosed
EP-1824812-A2 NIACIN RECEPTOR AGONISTS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT Merck & Co., Inc. (US) 2007-08-29 EP disclosed
EP-1788049-A1 THERMOSETTING AQUEOUS COATING COMPOSITION Kansai Paint Co., Ltd. (JP) 2007-05-23 EP disclosed
EP-1780249-A1 WATER-BASED PRIMER COMPOSITION KANSAI PAINT CO., LTD. (JP) 2007-05-02 EP disclosed
EP-1770135-A1 THERMOSETTING WATER-BASED COATING COMPOSITION AND METHOD OF FORMING COATING FILM Kansai Paint Co., Ltd. (JP) 2007-04-04 EP disclosed
US-20070060595-A1 Novel fused heterocyclic compound and use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2007-03-15 US disclosed
WO-2007002557-A1 NIACIN RECEPTOR AGONISTS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT MERCK & CO., INC. (US) 2007-01-04 WO disclosed
US-20060293364-A1 Niacin receptor agonists, compositions containing such compounds and methods of treatment MERCK & CO., INC. 2006-12-28 US disclosed
US-7102008-B2 Hydantoin derivatives as inhibitors of matrix metalloproteinases and/or TNF-α converting enzyme BRISTOL-MYERS SQUIBB COMPANY (US) 2006-09-05 US disclosed
US-7094773-B2 LTA4 hydrolase inhibitors Institut National de la Santa et de la rescherche Medicale Bioprojet (FR) 2006-08-22 US disclosed
EP-1671962-A1 NOVEL FUSED HETEROCYCLIC COMPOUND AND USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2006-06-21 EP disclosed
WO-2006057922-A2 NIACIN RECEPTOR AGONISTS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT MERCK & CO., INC. (US) 2006-06-01 WO disclosed
US-20060052398-A1 Novel vitronectin receptor antagonist derivatives, method for preparing same, use thereof as medicines and pharmaceutical compositions containing same GALAPAGOS NV (BE) 2006-03-09 US disclosed
CN-1678814-A Viscosity reduction of viscoelastic surfactant based fluids SCHLUMBERGER TECHNOLOGY BV (NL) 2005-10-05 CN disclosed
US-6908888-B2 Viscosity reduction of viscoelastic surfactant based fluids SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2005-06-21 US disclosed
EP-1534926-A1 VISCOSITY REDUCTION OF VISCOELASTIC SURFACTANT BASED FLUIDS SERVICES PETROLIERS SCHLUMBERGER (FR) 2005-06-01 EP disclosed
US-6881709-B2 Viscosity reduction of viscoelastic surfactant based fluids SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2005-04-19 US disclosed
US-6878723-B1 Carbocyclic and/or heterocyclic amino carboxylic acids, e.g., 2-aminomethyl-6-(p-benzylphenoxy)hexanoic acid; leukotriene A4 hydrolase; treating arthritis and psoriasis; hematoprotective and antimitotic agents INSTITUT NATIONAL DE LA SANTE ET DE LA RESCHERCHE MEDICALE (INSERM) (FR) 2005-04-12 US disclosed
US-20050027013-A1 LTA4 hydrolase inhibitors DANVY DENIS (FR) 2005-02-03 US disclosed
EP-1026198-B1 Polypropylene resin composition and injection-molded article thereof MITSUI CHEMICALS INC (JP) 2004-12-15 EP disclosed
US-6759475-B2 MECHANICAL PROPERTIES AND IN THE FLOWABILITY UPON INJECTION MOLDING AND CAN SERVE FOR A MATERIAL FOR EXHIBITING BETTER APPEARANCE MITSUI CHEMICALS, INC. (JP) 2004-07-06 US disclosed
US-20040063698-A1 Hydantoin derivatives as inhibitors of matrix metalloproteinases and/or TNF-alpha converting enzyme BRISTOL-MYERS SQUIBB COMPANY 2004-04-01 US disclosed
EP-0916701-B1 CRYSTALLINE POLYPROPYLENE RESIN COMPOSITION MITSUI CHEMICALS INC (JP) 2004-02-25 EP disclosed
WO-2004012663-A2 HYDANTOIN DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES AND/OR TNF-ALPHA CONVERTING ENZYME BRISTOL-MYERS SQUIBB COMPANY (US) 2004-02-12 WO disclosed
WO-2004007904-A1 VISCOSITY REDUCTION OF VISCOELASTIC SURFACTANT BASED FLUIDS SCHLUMBERGER CANADA LIMITED (CA) 2004-01-22 WO disclosed
EP-0919572-B1 POLYPROPYLENE RESIN COMPOSITION AND INJECTION-MOLDED ARTICLE MITSUI CHEMICALS INC (JP) 2003-12-10 EP disclosed
CN-1427919-A Viscocity reduction of viscoelastic surfactant based fluids SOFITECH NV (BE) 2003-07-02 CN disclosed
EP-1268976-A2 VISCOSITY REDUCTION OF VISCOELASTIC SURFACTANT BASED FLUIDS Sofitech N.V. (BE) 2003-01-02 EP disclosed
US-20020193257-A1 Viscosity reduction of viscoelastic surfactant based fluids SCHLUMBERGER TECHNOLOGY CORPORATION 2002-12-19 US disclosed
EP-1105359-B1 SOLID PHASE SYNTHESIS OF COMPOUNDS BY CARBON-CARBON BOND FORMING MITSUNOBU REACTIONS PE CORP NY (US) 2002-10-30 EP disclosed
US-20020058741-A1 Resin composition based on crystalline polypropylene MITSUI CHEMICALS, INC. (JP) 2002-05-16 US disclosed
US-20020004464-A1 Viscosity reduction of viscoelastic surfactant based fluids SCHLUMBERGER TECHNOLOGY CORPORATION 2002-01-10 US disclosed
US-6320009-B1 LIGHT WEIGHT, VERY HIGH VALUES OF STIFFNESS AND HEAT RESISTANCE, SUPERIOR SCRATCHPROONESS, SUPERIOR IN MELT PROCESSIBILITY; INJECTION MOLDINGS GRAND POLYMER CO LTD (JP) 2001-11-20 US disclosed
WO-2001077487-A2 VISCOSITY REDUCTION OF VISCOELASTIC SURFACTANT BASED FLUIDS SOFITECH N.V. (BE) 2001-10-18 WO disclosed
WO-2001072704-A1 AZETIDINONE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND A METHOD FOR PRODUCING 1-β-ALKYL AZETIDINONE USING THE SAME DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2001-10-04 WO disclosed
EP-1105359-A1 SOLID PHASE SYNTHESIS OF COMPOUNDS BY CARBON-CARBON BOND FORMING MITSUNOBU REACTIONS PE Corporation (NY) (US) 2001-06-13 EP disclosed
US-6121055-A DETECTING COMPOUND IN SAMPLE; MIXING SAMPLE AND CHEMICAL INTERMEDIATE, SEPARATING INSOLUBLE COMPONENT OF MIXTURE, ADDING BINDING COMPONENT AND LABEL TO MIX, SEPARATE BINDING COMPONENT AND LABEL, DETECT BOUND LABEL AND BINDING COMPONENT ROCHE DIAGNOSTICS CORPORATION (US) 2000-09-19 US disclosed
EP-1026198-A1 Polypropylene resin composition and injection-molded article thereof Grand Polymer Co., Ltd. (JP) 2000-08-09 EP disclosed
EP-0674233-B1 Recording sheets XEROX CORP (US) 2000-05-24 EP disclosed
WO-2000010942-A1 SOLID PHASE SYNTHESIS OF COMPOUNDS BY CARBON-CARBON BOND FORMING MITSUNOBU REACTIONS THE PERKIN-ELMER CORPORATION (US) 2000-03-02 WO disclosed
US-6025487-A Isomerisation process GLAXO WELLCOME SPA (IT) 2000-02-15 US disclosed
US-5928765-A Recording sheets XEROX CORPORATION (US) 1999-07-27 US disclosed
EP-0919572-A1 POLYPROPYLENE RESIN COMPOSITION AND INJECTION-MOLDED ARTICLE Grand Polymer Co., Ltd. (JP) 1999-06-02 EP disclosed
EP-0916701-A1 CRYSTALLINE POLYPROPYLENE RESIN COMPOSITION Grand Polymer Co., Ltd. (JP) 1999-05-19 EP disclosed
EP-0903382-A1 Semi-solid hot melt ink compositions containing esters XEROX CORPORATION (US) 1999-03-24 EP disclosed
US-5876492-A Ink compositions containing esters XEROX CORPORATION (US) 1999-03-02 US disclosed
EP-0871635-A1 ISOMERISATION PROCESS GLAXO WELLCOME S.p.A. (IT) 1998-10-21 EP disclosed
WO-1997006174-A1 ISOMERISATION PROCESS GLAXO WELLCOME SPA (IT) 1997-02-20 WO disclosed
EP-0674233-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP disclosed
US-5451458-A Electrography XEROX CORPORATION (US) 1995-09-19 US disclosed
US-5449680-A Antiallergens, antiinflammatory agents; platelet activating factor antagonists SCHERING CORPORATION (US) 1995-09-12 US disclosed
US-5320775-A Malonate esters LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1994-06-14 US disclosed
EP-0216423-B1 PESTICIDAL BENZOYLUREA COMPOUNDS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-05-12 EP disclosed
US-5185334-A 2,2-disubstituted glycerol and glycerol-like compounds, compositions and methods of use SCHERING CORPORATION (US) 1993-02-09 US disclosed
EP-0517482-A2 Bleach precursors UNILEVER PLC (GB) 1992-12-09 EP disclosed
US-5073341-A Immunology, diagnosis BIOTOPE, INC. (US) 1991-12-17 US disclosed
EP-0398990-A1 2,2-DISUBSTITUTED GLYCEROL AND GLYCEROL-LIKE COMPOUNDS, COMPOSITIONS AND METHODS OF USE SCHERING CORPORATION (US) 1990-11-28 EP disclosed
EP-0206810-B1 ACRYLATE COMPOUND AND COMPOSITION CONTAINING THE SAME TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1990-04-04 EP disclosed
EP-0344276-A1 METHODS AND DEVICES FOR CONDUCTING ASSAYS BOEHRINGER MANNHEIM CORPORATION (US) 1989-12-06 EP disclosed
US-4873327-A Pesticidal benzoylurea compounds E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-10-10 US disclosed
US-4868130-A DENSITY SEPARATION BIOTOPE, INC. (US) 1989-09-19 US disclosed
EP-0327962-A1 2,2-Disubstituted glycerol and glycerol-like compounds, compositions and methods of use SCHERING CORPORATION (US) 1989-08-16 EP disclosed
WO-1989007099-A1 2,2-DISUBSTITUTED GLYCEROL AND GLYCEROL-LIKE COMPOUNDS, COMPOSITIONS AND METHODS OF USE SCHERING CORPORATION (US) 1989-08-10 WO disclosed
WO-1989007100-A1 2,2-DISUBSTITUTED GLYCEROL AND GLYCEROL-LIKE COMPOUNDS, COMPOSITIONS AND METHODS OF USE SCHERING CORPORATION (US) 1989-08-10 WO disclosed
US-4849401-A Alcohols containing 2-methylphenyl or 2-methoxyphenyl groups, and fragrances containing same CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE, GMBH (DE) 1989-07-18 US disclosed
US-4755620-A Acrylate compound and composition containing the same TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1988-07-05 US disclosed
US-4745113-A MITICIDES, INSECTICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-05-17 US disclosed
EP-0216423-A2 Pesticidal benzoylurea compounds SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-04-01 EP disclosed
EP-0210025-A2 5-Substituted-6-aminopyrimidine derivatives, composition and uses AMERICAN HOME PRODUCTS CORPORATION (US) 1987-01-28 EP disclosed
EP-0206810-A2 Acrylate compound and composition containing the same TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1986-12-30 EP disclosed
US-4617393-A CONGESITIVE HEART FAILURE AMERICAN HOME PRODUCTS CORPORATION (US) 1986-10-14 US disclosed
EP-0008446-B1 PROCESS FOR THE PREPARATION OF CARBAZOLES AND NOVEL CARBAZOLE DERIVATIVES UTILIZED THEREIN F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1982-09-22 EP disclosed
US-4299926-A STERICALLY HINDERED POLYALKYLPIPERIDINE CIBA-GEIGY CORPORATION (US) 1981-11-10 US disclosed
US-4282156-A Method for the production of novel anhydride polycarboxylates LEVER BROTHERS COMPANY (US) 1981-08-04 US disclosed
US-4272442-A Certain tricarboxylic acid derivatives LEVER BROTHERS COMPANY (US) 1981-06-09 US disclosed
US-4260689-A PIPERIDONE-CONTAINING POLYAMINES CIBA-GEIGY CORPORATION (US) 1981-04-07 US disclosed
US-4260691-A POLYURETHANES WITH PIPERIDINE-CONTAINING MONOMERS CIBA-GEIGY CORPORATION (US) 1981-04-07 US disclosed
US-4250268-A Polysilylesters having a polyalkylpiperidine as part of the polymer useful as light stabilizers for plastics CIBA-GEIGY CORPORATION (US) 1981-02-10 US disclosed
US-4236027-A Novel 11-alkoxy-9-keto (or hydroxy)-prostenoic acid derivatives and method for preparing same AMERICAN CYANAMID COMPANY (US) 1980-11-25 US disclosed
US-4234700-A POLYCARBONATE OR POLYUREA CONTAINING POLYALKYLPIPERIDINE GROUPS CIBA-GEIGY CORPORATION (US) 1980-11-18 US disclosed
US-4234699-A POLYETHERS CONTAINING POLYALKYLPIPERIDINE GROUPS CIBA-GEIGY CORPORATION (US) 1980-11-18 US disclosed
US-4233410-A STERICALLY HINDERED POLYUREAS OF LOW MOLECULAR WEIGHT CIBA-GEIGY CORPORATION (US) 1980-11-11 US disclosed
US-4233412-A POLYESTERS CONTAINING STERICALLY HINDERED ALKYLPIPERIDINE GROUPS CIBA-GEIGY CORPORATION (US) 1980-11-11 US disclosed
US-4232131-A POLYAMIDE CIBA-GEIGY CORPORATION (US) 1980-11-04 US disclosed
US-4226781-A 1,1,2,3-Propane tetracarboxylic acid compounds LEVER BROTHERS COMPANY (US) 1980-10-07 US disclosed
US-4226774-A Carbazole melonates HOFFMANN-LA ROCHE INC. (US) 1980-10-07 US disclosed
US-4193923-A Tetrahydro 2-carbazolyl methyl malonate derivatives HOFFMANN-LA ROCHE INC. (US) 1980-03-18 US disclosed
EP-0008446-A1 Process for the preparation of carbazoles and novel carbazole derivatives utilized therein F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1980-03-05 EP disclosed
US-4182805-A Decyanation POLAROID CORPORATION (US) 1980-01-08 US disclosed
US-4158007-A Carbazole methyl malonates HOFFMANN-LA ROCHE INC. (US) 1979-06-12 US disclosed
US-4152524-A BRONCHODILATORS, HYPOTENSIVE AMERICAN CYANAMID COMPANY (US) 1979-05-01 US disclosed
US-4146543-A Reaction of maleic anhydride with active methylene or methine containing compounds LEVER BROTHERS COMPANY (US) 1979-03-27 US disclosed
US-4134894-A Pyrrolo[1,2-a]indole compounds WARNER-LAMBERT COMPANY (US) 1979-01-16 US disclosed
US-4110424-A PROCESS FOR THE PRODUCTION OF CYANIC ACID AND CARBOXAMIDES POLAROID CORPORATION (US) 1978-08-29 US disclosed
US-4076947-A BRONCHODILATORS, HYPOTENSIVE AGENTS, ANTIULCER AGENTS AMERICAN CYANAMID COMPANY (US) 1978-02-28 US disclosed
US-3997682-A Oleaginous food flavored with certain alpha carboxy acids and/or esters thereof ANDERSON, CLAYTON & CO. (US) 1976-12-14 US disclosed
US-3997682-A Oleaginous food flavored with certain alpha carboxy acids and/or esters thereof ANDERSON, CLAYTON & CO. (US) 1976-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (50 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060052398-A1 Novel vitronectin receptor antagonist derivatives, method for preparing same, use thereof as medicines and pharmaceutical compositions containing same ADGRF1, C5AR2, ADGRE5 MGAM 3114/4885GAA 3727/4885SI 2055/4885
US-20140154240-A1 PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT TYMP, ZC3HAV1, TYMS MGAM 4137/4885GAA 1676/4885SI 1262/4885
US-20100041675-A1 treatment of retinopathy comprising administering drugs such as tert-butyl 3-[5-ethyl-6-[4-(5,6,7,8-tetrahydro-(1,8)naphthyridin-2-yl)-piperidin-1-yl]-pyrimidin-4-ylamino]-2-(4-methoxy benzoyl)-propionate TBXA2R, GPR55, ADGRE5 MGAM 4835/4885GAA 4482/4885SI 3531/4885
US-20060293364-A1 Niacin receptor agonists, compositions containing such compounds and methods of treatment HCAR1, HCAR2, FFAR1 MGAM 2937/4885GAA 1439/4885SI 1871/4885
US-20190263955-A1 POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF PCBP1, PARG, PARP1 MGAM 877/4885GAA 1306/4885SI 4175/4885
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US-20130345233-A1 INHIBITORS OF PROTEIN KINASES CDK1, CDK2, CDK3 MGAM 3335/4885GAA 1543/4885SI 4321/4885
US-20110039867-A1 PYRIMIDINE DERIVATIVES WHICH ARE ANTAGONIST OF THE VITRONECTIN RECEPTOR P2RY1, P2RY2, P2RX5 MGAM 4558/4885GAA 4439/4885SI 3429/4885
US-20070281969-A1 Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment GPR119, FFAR1, HCAR1 MGAM 3029/4885GAA 1257/4885SI 1714/4885
US-10556862-B2 Difluorolactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions PTGER4, PTGER1, PTGER3 MGAM 3832/4885GAA 3327/4885SI 4835/4885
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US-20150376208-A1 MK2 INHIBITORS AND USES THEREOF MKNK2, DUSP2, MKNK1 MGAM 1447/4885GAA 2587/4885SI 3848/4885
US-20170275446-A1 POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF PCBP1, PARG, PARP1 MGAM 822/4885GAA 1196/4885SI 4041/4885
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US-11066361-B2 Difluorolactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions PTGER4, PTGER1, PTGER3 MGAM 3832/4885GAA 3327/4885SI 4835/4885
US-20150175538-A1 DIFLUOROLACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS PTGER4, PTGER1, PTGER3 MGAM 3832/4885GAA 3327/4885SI 4835/4885
US-20070060595-A1 Novel fused heterocyclic compound and use thereof JUN, CHUK, RELA MGAM 3656/4885GAA 4069/4885SI 1299/4885
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US-20160031811-A1 LACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS PTGER4, PTGER1, PTGER3 MGAM 3532/4885GAA 3038/4885SI 4504/4885
US-20150174099-A1 DIFLUOROLACTAM COMPOSITIONS FOR EP4-MEDIATED OSTEO RELATED DISEASES AND CONDITIONS PTGER4, PTGER1, PTGER3 MGAM 1660/4885GAA 4011/4885SI 3309/4885
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US-20170260173-A1 DIFLUOROLACTAM COMPOSITIONS FOR EP4-MEDIATED OSTEO RELATED DISEASES AND CONDTIONS PTGER4, PTGER1, EPB41 MGAM 2351/4885GAA 2090/4885SI 4294/4885
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US-20140072554-A1 PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT TYMP, ZC3HAV1, TYMS MGAM 4137/4885GAA 1676/4885SI 1262/4885
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US-20050027013-A1 LTA4 hydrolase inhibitors LTA4H, LTC4S, LTB4R MGAM 1368/4885GAA 611/4885SI 1544/4885
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US-20120115903-A1 Substituted Heteroaromatic Carboxamide and Urea Compounds as Vanilloid Receptor Ligands TRPV1, OPRM1, OPRK1 MGAM 4583/4885GAA 2797/4885SI 1966/4885
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US-11884624-B2 Difluorolactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions PTGER4, PTGER1, PTGER3 MGAM 3832/4885GAA 3327/4885SI 4835/4885
US-20160024006-A1 DIFLUOROLACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS PTGER4, PTGER1, PTGER3 MGAM 3832/4885GAA 3327/4885SI 4835/4885
US-20110224225-A1 Inhibitors of protein kinases CDK1, CDK2, CDK3 MGAM 3335/4885GAA 1543/4885SI 4321/4885
US-11345690-B2 Methods of synthesizing a difluorolactam analog PTGER4, PTGER1, PTGIR MGAM 3290/4885GAA 2967/4885SI 4212/4885
US-20160340306-A1 DIFLUOROLACTAM COMPOSITIONS FOR EP4-MEDIATED OSTEO RELATED DISEASES AND CONDITIONS PTGER4, PTGER1, PTGER3 MGAM 1751/4885GAA 2212/4885SI 4420/4885
US-20120115883-A1 PYRIMIDINE DERIVATIVES WHICH ARE ANTAGONISTS OF THE VITRONECTIN RECEPTOR P2RY1, P2RY2, P2RX5 MGAM 4459/4885GAA 4383/4885SI 3309/4885
US-10633566-B2 Polymers containing a 1,1-disubstituted alkene compound ALG8, PCNA, PARP1 MGAM 236/4885GAA 955/4885SI 2921/4885
US-20080058348-A1 Bone disorders such as osteoporosis, tumors and cardiovascular disorders; 4-(2-carboxy-2-Boc-aminoethylamino)-6-piperidinopyrimidines such as tert-butyl 2-benzyloxycarbonylamino-3-[2,5-dimethoxy-6-(4-[1,8]naphthyridin-2-yl-piperidin-1-yl)pyrimidin-4-ylamino]-propionate CALCR, PTH1R, CALCRL MGAM 4852/4885GAA 4405/4885SI 3503/4885
US-11021617-B2 Polymers including one or more 1,1-disubstituted alkene compounds and polymer compositions thereof PCBP1, PARG, PARP1 MGAM 877/4885GAA 1306/4885SI 4175/4885
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US-20180298015-A1 PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS IRAK1, IRAK4, IRAK2 MGAM 4665/4885GAA 4404/4885SI 4542/4885
US-20150203490-A1 RING-FUSED COMPOUND URB2, RCOR1, RCC2 MGAM 4500/4885GAA 2071/4885SI 4695/4885
US-20180170918-A1 METHODS OF SYNTHESIZING A DIFLUOROLACTAM ANALOG PTGER4, PTGER1, PTGIR MGAM 3290/4885GAA 2967/4885SI 4212/4885
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US-20190144435-A1 DIFLUOROLACTAM COMPOSITIONS FOR EP4-MEDIATED OSTEO RELATED DISEASES AND CONDITIONS PTGER4, PTGER1, PTGER3 MGAM 1751/4885GAA 2212/4885SI 4420/4885
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“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.