Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29401163 | 1.00 | GSR (0.65) | — | |
| Hydrochloric Acid SCHEMBL318747 | 1.00 | GSR (0.65) | — | |
| Hydrochloric Acid SCHEMBL318746 | 1.00 | GSR (0.65) | — | |
| Hydrochloric Acid SCHEMBL2398999 | 1.00 | — | — | |
| SCHEMBL34705 | 0.97 | — | — | |
| SCHEMBL288792 | 0.97 | — | — | |
| SCHEMBL34706 | 0.97 | — | — | |
| SCHEMBL29479228 | 0.97 | — | — | |
| Bromide SCHEMBL7013646 | 0.94 | — | — | |
| Bromide SCHEMBL29401581 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110317143-B | Preparation method of L-2, 4-diaminobutyric acid hydrochloride | 成都百事兴科技实业有限公司 | 2022-06-10 | — | — | CN | claimed |
| CN-110317143-A | A kind of preparation method of L-2,4- diaminobutyric acid hydrochloride | 成都百事兴科技实业有限公司 | 2019-10-11 | — | — | CN | claimed |
| WO-2023075435-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTE | 주식회사 베르티스 | 2023-05-04 | — | — | WO | disclosed |
| US-20220283131-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTES | BERTIS CO., LTD. (KR) | 2022-09-08 | — | — | US | disclosed |
| CN-110317143-B | Preparation method of L-2, 4-diaminobutyric acid hydrochloride | 成都百事兴科技实业有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-110317143-B | Preparation method of L-2, 4-diaminobutyric acid hydrochloride | 成都百事兴科技实业有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-110317143-B | Preparation method of L-2, 4-diaminobutyric acid hydrochloride | 成都百事兴科技实业有限公司 | 2022-06-10 | — | — | CN | disclosed |
| WO-2022050529-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTE | ㈜베르티스 | 2022-03-10 | — | — | WO | disclosed |
| CN-110317143-A | A kind of preparation method of L-2,4- diaminobutyric acid hydrochloride | 成都百事兴科技实业有限公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-110317143-A | A kind of preparation method of L-2,4- diaminobutyric acid hydrochloride | 成都百事兴科技实业有限公司 | 2019-10-11 | — | — | CN | disclosed |
| US-8026233-B2 | P38 inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2011-09-27 | — | — | US | disclosed |
| US-20090149443-A1 | P38 INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA, INC. | 2009-06-11 | — | — | US | disclosed |
| CN-101454313-A | P38 inhibitors and methods of use thereof | ARRAY BIOPHARMA INC (US) | 2009-06-10 | — | — | CN | disclosed |
| US-7384639-B2 | Methods of treating or preventing an infectious disease using an immunogenic conjugate of a gram-negative bacterial autoinducer molecule | UNIVERSITY OF ROCHESTER (US) | 2008-06-10 | — | — | US | disclosed |
| US-20070231839-A1 | Methods of treating or preventing an infectious disease using an immunogenic conjugate of a gram-negative bacterial autoinducer molecule or antibodies that immunospecifically bind a gram-negative bacterial autoinducer molecule | UNIVERSITY OF ROCHESTER (US) | 2007-10-04 | — | — | US | disclosed |
| US-6958219-B2 | Method for detecting a gram-negative bacterial autoinducer molecule | UNIVERSITY OF ROCHESTER (US) | 2005-10-25 | — | — | US | disclosed |
| US-20040156856-A1 | Immunogenic conjugates of gram-negative bacterial autoinducer molecules and antibodies raised against the same | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2004-08-12 | — | — | US | disclosed |
| US-6713059-B2 | CARRIER MOLECULE COUPLED TO AN AUTOINDUCER OF A GRAM NEGATIVE BACTERIA; E.G., N-(3-OXODODECANOYL)-L-HOMOSERINE LACTONE, N-(BUTANOYL)-L-HOMOSERINE LACTONE, OR N-HEXANOYL-HOMOSERINE LACTONE | UNIVERSITY OF ROCHESTER | 2004-03-30 | — | — | US | disclosed |
| US-20030095985-A1 | Immunogenic conjugates of Gram-negative bacterial autoinducer molecules and antibodies raised against the same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-05-22 | — | — | US | disclosed |
| US-6395282-B1 | CARRIER MOLECULE CONJUGATED TO SPECIFIC AUTOINDUCERS; VACCINES FOR THE TREATMENT AND PREVENTION OF INFECTION | UNIVERSITY OF ROCHESTER | 2002-05-28 | — | — | US | disclosed |