Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A known ✓ | P28223 | 2/20 | 0.44 |
| ▸ | RET known ✓ | P07949 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28670875 | 1.00 | IDO1 (0.59) | IDO1MEN1ALDH1A1CYP2D6BLM | |
| Hydrochloric Acid SCHEMBL7424398 | 1.00 | IDO1 (0.59) | IDO1MEN1ALDH1A1CYP2D6BLM | |
| Hydrochloric Acid SCHEMBL29771948 | 1.00 | IDO1 (0.59) | IDO1MEN1ALDH1A1CYP2D6BLM | |
| Hydrochloric Acid SCHEMBL29757860 | 1.00 | IDO1 (0.59) | IDO1MEN1ALDH1A1CYP2D6BLM | |
| Hydrochloric Acid SCHEMBL1874441 | 1.00 | IDO1 (0.59) | IDO1MEN1ALDH1A1CYP2D6BLM | |
| SCHEMBL29415502 | 0.98 | IDO1 (0.58) | IDO1HTR2ARET | |
| SCHEMBL469047 | 0.98 | IDO1 (0.58) | IDO1HTR2ARET | |
| SCHEMBL30837489 | 0.98 | IDO1 (0.58) | IDO1HTR2ARET | |
| SCHEMBL44600 | 0.98 | IDO1 (0.58) | IDO1HTR2ARET | |
| SCHEMBL10774751 | 0.98 | IDO1 (0.58) | IDO1HTR2ARET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112111557-A | Surfactant-free urine analysis quality control liquid | 成都恩普瑞生物工程有限公司 | 2020-12-22 | — | — | CN | claimed |
| US-20200131431-A1 | CHEMICAL ADDITIVES AND SURFACTANT COMBINATIONS FOR FAVORABLE WETTABILITY ALTERATION AND IMPROVED HYDROCARBON RECOVERY FACTORS | ALCHEMY SCIENCES INC (US) | 2020-04-30 | — | — | US | claimed |
| US-20040248310-A1 | Method for detection of bromine in urine using liquid chemistry, dry chemistry test pads, and lateral flow | SMITH JACK V (US) | 2004-12-09 | — | — | US | claimed |
| US-20030186451-A1 | Method for detection of bromine in urine using liquid chemistry, dry chemistry test pads. and lateral flow | SMITH JACK V (US) | 2003-10-02 | — | — | US | claimed |
| US-6537823-B1 | Use in determination of adulterants in illicit drug screening samples as a means of detecting false negative results | SCITECK DIAGNOSTICS, INC. | 2003-03-25 | — | — | US | claimed |
| US-20030045003-A1 | Method for detection of the adulterant urine luckTM in urine using liquid chemistry, dry chemistry test pads, and lateral flow | SMITH JACK V (US) | 2003-03-06 | — | — | US | claimed |
| US-20030027350-A1 | Method for detection of bromine in urine using liquid chemistry, dry chemistry test pads, and lateral flow | SMITH JACK V (US) | 2003-02-06 | — | — | US | claimed |
| US-5652093-A | Analogues of reporter groups as background reducers in binding assays | APROGENEX, INC. (US) | 1997-07-29 | — | — | US | claimed |
| US-5501952-A | Analogues of reporter groups as background reducers in hybridization assays | APROGENEX, INC. (US) | 1996-03-26 | — | — | US | claimed |
| CN-114703492-A | Dasotriprin electrochemical preparation method | 湖南大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-112111557-A | Surfactant-free urine analysis quality control liquid | 成都恩普瑞生物工程有限公司 | 2020-12-22 | — | — | CN | disclosed |
| US-20200131431-A1 | CHEMICAL ADDITIVES AND SURFACTANT COMBINATIONS FOR FAVORABLE WETTABILITY ALTERATION AND IMPROVED HYDROCARBON RECOVERY FACTORS | ALCHEMY SCIENCES INC (US) | 2020-04-30 | — | — | US | disclosed |
| CN-103119015-B | Method for resolving nitrogen substituted (S) -5-alkoxy-2-aminotetralin derivatives | UCB PHARMA GMBH (DE) | 2016-01-27 | — | — | CN | disclosed |
| CN-103415286-A | Compounds and methods for treating pain | AKRON MOLECULES GMBH | 2013-11-27 | — | — | CN | disclosed |
| US-5637609-A | CARRYING OUT A MANNICH REACTION, VILSMEIER REACTION, REDUCING THE INTERMEDIATE FORMED, FOLLOWED BY REDUCTIVE AMINATION; ANTIPSYCHOTIC AGENT | SMITHKLINE BEECHAM PLC (GB) | 1997-06-10 | — | — | US | disclosed |
| EP-0711279-A1 | 2-PHENYLPYRROLE DERIVATIVES AS DOPAMINE D3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-05-15 | — | — | EP | disclosed |
| US-5501952-A | Analogues of reporter groups as background reducers in hybridization assays | APROGENEX, INC. (US) | 1996-03-26 | — | — | US | disclosed |
| WO-1995004039-A1 | 2-PHENYLPYRROLE DERIVATIVES AS DOPAMINE D3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-02-09 | — | — | WO | disclosed |
| WO-1995002699-A1 | ANALOGUES OF REPORTER GROUPS AS BACKGROUNG REDUCERS IN HYBRIDIZATION ASSAYS | APROGENEX, INC. (US) | 1995-01-26 | — | — | WO | disclosed |
| US-4661520-A | Cyanoguanidine useful as an animal growth promoting agent | THE DOW CHEMICAL COMPANY (US) | 1987-04-28 | — | — | US | disclosed |