Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Trimethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL27639780 | 1.00 | — | — | |
| Trimethylammonium SCHEMBL11755984 | 1.00 | — | — | |
| Trimethylammonium SCHEMBL1034705 | 1.00 | — | — | |
| Trimethylammonium SCHEMBL4782409 | 1.00 | — | — | |
| Trimethylammonium SCHEMBL10670242 | 1.00 | — | — | |
| Trimethylammonium SCHEMBL11045756 | 1.00 | — | — | |
| Trimethylammonium SCHEMBL1332702 | 1.00 | — | — | |
| Trimethylammonium SCHEMBL17005746 | 1.00 | — | — | |
| Trimethylammonium SCHEMBL6558626 | 1.00 | — | — | |
| Trimethylammonium SCHEMBL1330883 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10784388-B2 | Photovoltaic devices with depleted heterojunctions and shell-passivated nanoparticles | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2020-09-22 | — | — | US | claimed |
| US-20160372616-A1 | PHOTOVOLTAIC DEVICES WITH DEPLETED HETEROJUNCTIONS AND SHELL-PASSIVATED NANOPARTICLES | INNOVATION ASSET COLLECTIVE (CA) | 2016-12-22 | — | — | US | claimed |
| EP-2556131-A1 | PHOTOVOLTAIC DEVICES WITH DEPLETED HETEROJUNCTIONS AND SHELL-PASSIVATED NANOPARTICLES | The Governing Council Of The University Of Toronto (CA) | 2013-02-13 | — | — | EP | claimed |
| WO-2011126778-A1 | PHOTOVOLTAIC DEVICES WITH DEPLETED HETEROJUNCTIONS AND SHELL-PASSIVATED NANOPARTICLES | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2011-10-13 | — | — | WO | claimed |
| US-20110240106-A1 | PHOTOVOLTAIC DEVICES WITH DEPLETED HETEROJUNCTIONS AND SHELL-PASSIVATED NANOPARTICLES | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2011-10-06 | — | — | US | claimed |
| US-10784388-B2 | Photovoltaic devices with depleted heterojunctions and shell-passivated nanoparticles | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2020-09-22 | — | — | US | disclosed |
| US-20190077116-A1 | FOAMED ACRYLIC-RESIN OBJECT, PROCESS FOR PRODUCING SAME, AND FIBER-REINFORCED COMPOSITE | SEKISUI PLASTICS CO., LTD. (JP) | 2019-03-14 | — | — | US | disclosed |
| EP-3348611-A1 | FOAMED ACRYLIC-RESIN OBJECT, PROCESS FOR PRODUCING SAME, AND FIBER-REINFORCED COMPOSITE | Sekisui Plastics Co., Ltd. (JP) | 2018-07-18 | — | — | EP | disclosed |
| US-20160372616-A1 | PHOTOVOLTAIC DEVICES WITH DEPLETED HETEROJUNCTIONS AND SHELL-PASSIVATED NANOPARTICLES | INNOVATION ASSET COLLECTIVE (CA) | 2016-12-22 | — | — | US | disclosed |
| CN-106167704-A | Electrooptical device, nano-particle and the method forming nano-particle | 多伦多大学董事局 | 2016-11-30 | — | — | CN | disclosed |
| CN-102859710-B | Optoelectronic devices, nanoparticles, and methods of forming nanoparticles | 多伦多大学董事局 | 2016-10-19 | — | — | CN | disclosed |
| EP-2556131-B1 | PHOTOVOLTAIC DEVICES WITH DEPLETED HETEROJUNCTIONS AND SHELL-PASSIVATED NANOPARTICLES | UNIV TORONTO (CA) | 2016-10-12 | — | — | EP | disclosed |
| CN-102859710-A | Photovoltaic device with depletion heterojunction and shell-passivated nanoparticles | UNIV TORONTO | 2013-01-02 | — | — | CN | disclosed |
| WO-2011126778-A1 | PHOTOVOLTAIC DEVICES WITH DEPLETED HETEROJUNCTIONS AND SHELL-PASSIVATED NANOPARTICLES | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2011-10-13 | — | — | WO | disclosed |
| US-20110240106-A1 | PHOTOVOLTAIC DEVICES WITH DEPLETED HETEROJUNCTIONS AND SHELL-PASSIVATED NANOPARTICLES | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2011-10-06 | — | — | US | disclosed |
| EP-1354036-B1 | COMPOSITIONS, METHODS, AND KITS FOR ISOLATING NUCLEIC ACIDS USING SURFACTANTS AND PROTEASES | LIFE TECHNOLOGIES CORP (US) | 2010-05-26 | — | — | EP | disclosed |
| US-7303876-B2 | Compositions, methods, and kits for isolating nucleic acids using surfactants and proteases | APPLERA CORPORATION (US) | 2007-12-04 | — | — | US | disclosed |
| US-7001724-B1 | Compositions, methods, and kits for isolating nucleic acids using surfactants and proteases | APPLERA CORPORATION (US) | 2006-02-21 | — | — | US | disclosed |
| US-20050009045-A1 | Compositions, methods, and kits for isolating nucleic acids using surfactants and proteases | APPLERA CORPORATION | 2005-01-13 | — | — | US | disclosed |
| US-6762027-B2 | EXTRACTING PREFERENTIAL NUCLEOTIDE SEQUENCE FROM TISSUE; OBTAIN TISSUE SAMPLE, EXPOSE TO DISRUPTION MIXTURE, BIND NUCLEIC ACID TO SOLID PHASE, RECOVER NUCLEOTIDE SEQUENCES | APPLERA CORPORATION | 2004-07-13 | — | — | US | disclosed |