Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Chlorobenzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 known ✓ | Q9BY41 | 1/20 | 0.39 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.39 |
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.85 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.43 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.43 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.43 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | TDO2 | P48775 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorobenzene SCHEMBL11599346 | 1.00 | TSHR (0.85) | TSHRCYP1A2CYP2A6LMNACES2 | |
| Chlorobenzene SCHEMBL27817799 | 1.00 | TSHR (0.85) | TSHRCYP1A2CYP2A6LMNACES2 | |
| Chlorobenzene SCHEMBL28381195 | 0.96 | TSHR (0.92) | TSHRCYP1A2CYP2A6LMNACES2 | |
| Chlorobenzene SCHEMBL27392029 | 0.96 | TSHR (0.92) | TSHRCYP1A2CYP2A6LMNACES2 | |
| Chlorobenzene SCHEMBL3865818 | 0.96 | TSHR (0.92) | TSHRCYP1A2CYP2A6LMNACES2 | |
| Chlorobenzene SCHEMBL25243236 | 0.96 | TSHR (0.92) | TSHRCYP1A2CYP2A6LMNACES2 | |
| Chlorobenzene SCHEMBL3865821 | 0.96 | TSHR (0.92) | TSHRCYP1A2CYP2A6LMNACES2 | |
| Chlorobenzene SCHEMBL7648898 | 0.96 | — | — | |
| Chlorobenzene SCHEMBL6482069 | 0.96 | — | — | |
| Chlorobenzene SCHEMBL11200773 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024113743-A1 | METHOD FOR PREPARING HEXACHLOROCYCLOTRIPHOSPHAZENE | 浙江万盛股份有限公司 | 2024-06-06 | — | — | WO | claimed |
| CN-115819460-A | Preparation method of hexachlorocyclotriphosphazene | 浙江万盛股份有限公司 | 2023-03-21 | — | — | CN | claimed |
| CN-107946384-B | A kind of silicon-PEDOT:PSS hybrid solar cell and preparation method thereof | 苏州亚傲鑫企业管理咨询有限公司 | 2019-06-14 | — | — | CN | claimed |
| CN-107994119-A | A kind of organic inorganic hybridization solar cell and preparation method thereof | 佛山市宝粤美科技有限公司 | 2018-05-04 | — | — | CN | claimed |
| CN-107946384-A | A kind of silicon PEDOT:PSS hybrid solar cells and preparation method thereof | 佛山市宝粤美科技有限公司 | 2018-04-20 | — | — | CN | claimed |
| CN-101648978-A | Preparation method of high purity hexaphenoxycyclotriphosphazene | ZIBO LANYIN CHEMICAL CO LTD | 2010-02-17 | — | — | CN | claimed |
| WO-2024113743-A1 | METHOD FOR PREPARING HEXACHLOROCYCLOTRIPHOSPHAZENE | 浙江万盛股份有限公司 | 2024-06-06 | — | — | WO | disclosed |
| WO-2024113743-A1 | METHOD FOR PREPARING HEXACHLOROCYCLOTRIPHOSPHAZENE | 浙江万盛股份有限公司 | 2024-06-06 | — | — | WO | disclosed |
| CN-117843685-A | Preparation method of chlorophosphazene intermediate mixture solution and preparation method of phenoxy phosphazene mixture flame retardant | 浙江万盛股份有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-220656435-U | Device for recycling pyridine or pyridine derivative in hexachlorocyclo-triphosphazene synthetic waste residues | 浙江万盛股份有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-220277839-U | Device for recycling hexachlorocyclo triphosphazene synthetic waste residues | 浙江万盛股份有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-117105849-A | Process for recycling pyridine or pyridine derivative in hexachlorocyclo-triphosphazene synthetic waste residues | 浙江万盛股份有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-117019817-A | Process for recycling hexachlorocyclo triphosphazene synthetic waste residues | 浙江万盛股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-105932089-A | Back contact silicon heterojunction solar cell without interface doping and preparation method thereof | 深圳大学 | 2016-09-07 | — | — | CN | disclosed |
| CN-103346260-B | Hybrid inorganic-organic solar cell of organic film passivation and preparation method thereof | SUZHOU UNIVERSITY (CN) | 2016-03-02 | — | — | CN | disclosed |
| CN-103296211-B | Heterojunction solar battery device of organic-two dimensional crystal-inorganic hybridization and preparation method thereof | SUZHOU UNIVERSITY (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-103346260-A | Organic-inorganic hybrid solar cell with passivated organic thin film and preparation method thereof | UNIV SOOCHOW | 2013-10-09 | — | — | CN | disclosed |
| CN-103296211-A | Organic-two-dimensional crystal-inorganic hybrid heterojunction solar cell device and preparation method thereof | UNIV SOOCHOW | 2013-09-11 | — | — | CN | disclosed |
| CN-101648978-B | Preparation method of high purity hexaphenoxycyclotriphosphazene | ZIBO LANYIN CHEMICAL CO LTD | 2012-08-15 | — | — | CN | disclosed |
| CN-101648978-A | Preparation method of high purity hexaphenoxycyclotriphosphazene | ZIBO LANYIN CHEMICAL CO LTD | 2010-02-17 | — | — | CN | disclosed |