Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.38 |
| ▸ | PARP1 known ✓ | P09874 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28219786 | 0.98 | CYP3A4 (0.40) | TSHRCYP3A4CA1CA2ALDH1A1 | |
| SCHEMBL27642594 | 0.98 | TSHR (0.43) | TSHRCYP3A4CA1CA2ALDH1A1 | |
| SCHEMBL17685497 | 0.98 | TSHR (0.43) | TSHRCYP3A4CA1CA2ALDH1A1 | |
| SCHEMBL27642281 | 0.98 | TSHR (0.43) | TSHRCYP3A4CA1CA2ALDH1A1 | |
| SCHEMBL29376031 | 0.98 | TSHR (0.43) | TSHRCYP3A4CA1CA2ALDH1A1 | |
| SCHEMBL27642275 | 0.98 | TSHR (0.43) | TSHRCYP3A4CA1CA2ALDH1A1 | |
| SCHEMBL7432807 | 0.98 | TSHR (0.43) | TSHRCYP3A4CA1CA2ALDH1A1 | |
| SCHEMBL7712 | 0.98 | TSHR (0.43) | TSHRCYP3A4CA1CA2ALDH1A1 | |
| SCHEMBL29555130 | 0.98 | TSHR (0.43) | TSHRCYP3A4CA1CA2ALDH1A1 | |
| Hydrogen Sulfide SCHEMBL23071424 | 0.96 | TSHR (0.41) | TSHRCYP3A4CA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1507474-A | Disazo compound, reactive dye composition, and methods of dyeing cellulose or cellulose-containing fiber | �ձ���ҩ��ʽ���� | 2004-06-23 | — | — | CN | claimed |
| CN-105358649-B | The crosslinking of acrylic adhesive composition, the manufacturing method of adhesive phase, the polarizing coating with adhesive phase and acrylic adhesive composition promotes method | 日东电工株式会社 | 2019-11-22 | — | — | CN | disclosed |
| CN-110462473-A | Adhesive layer-attached single-sided protective polarizing film, image display device, and continuous production method therefor | NITTO DENKO CORP | 2019-11-15 | — | — | CN | disclosed |
| CN-104937493-B | Composition for forming resist upper layer film for lithography and method for manufacturing semiconductor device | 日产化学工业株式会社 | 2019-11-08 | — | — | CN | disclosed |
| CN-110382648-A | Adhesive layer, single-sided protective polarizing film with adhesive layer, image display device, and continuous production method therefor | 日东电工株式会社 | 2019-10-25 | — | — | CN | disclosed |
| CN-110383121-A | Unilateral protection polarizing coating, image display device and its method for continuous production with adhesive phase | 日东电工株式会社 | 2019-10-25 | — | — | CN | disclosed |
| CN-110383120-A | Polarizing coating and image display device with adhesive phase | 日东电工株式会社 | 2019-10-25 | — | — | CN | disclosed |
| CN-107407753-B | Near-infrared shielding film, method for producing same, and adhesive composition | 柯尼卡美能达株式会社 | 2019-10-01 | — | — | CN | disclosed |
| CN-110291167-A | Adhesive composition for polarizing film, adhesive layer for polarizing film, polarizing film with adhesive layer, liquid crystal panel, and liquid crystal display device | 日东电工株式会社 | 2019-09-27 | — | — | CN | disclosed |
| CN-110268292-A | Polarizing film with optical function layer and liquid crystal display device | 日东电工株式会社 | 2019-09-20 | — | — | CN | disclosed |
| CN-1245800-A | Method for preparing substituted piperidine | HOFFMANN LA ROCHE (CH) | 2000-03-01 | — | — | CN | disclosed |
| CN-1224718-A | Thiazole derivatives | HOFFMANN LA ROCHE (CH) | 1999-08-04 | — | — | CN | disclosed |
| CN-1043349-C | New sulfuric acid esters of sugar alcohols | HOFFMANN LA ROCHE (CH) | 1999-05-12 | — | — | CN | disclosed |
| CN-1185745-A | Foamed polymer and process for producing the same | WOODBRIDGE FOAM CORP (CA) | 1998-06-24 | — | — | CN | disclosed |
| CN-1181765-A | Process for preparing a storage-stable mixture of polyisocyanate and phosphate | DOW CHEMICAL CO (US) | 1998-05-13 | — | — | CN | disclosed |
| CN-1119658-A | Organopolysiloxane compositions which can be crosslinked to elastomers with elimination of alcohols | WACKER CHEMIE GMBH (DE) | 1996-04-03 | — | — | CN | disclosed |
| CN-1109889-A | New sulfuric acid esters of sugar alcohols | HOFFMANN LA ROCHE (CH) | 1995-10-11 | — | — | CN | disclosed |
| CN-1073137-A | The laminating material and the polymkeric substance that contains perfluoro cyclobutane ring that contain the perfluorocyclobutane cyclopolymer | DOW CHEMICAL CO (US) | 1993-06-16 | — | — | CN | disclosed |
| CN-1020632-C | FUEL PRODUCTS | LUBRIZOL CORP (US) | 1993-05-12 | — | — | CN | disclosed |
| CN-86106817-A | FUEL PRODUCTS | — | 1987-05-27 | — | — | CN | disclosed |