Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299996 | 0.97 | — | — | |
| SCHEMBL24282474 | 0.80 | — | — | |
| SCHEMBL7776544 | 0.69 | — | — | |
| SCHEMBL7560953 | 0.65 | — | — | |
| SCHEMBL5197659 | 0.65 | — | — | |
| SCHEMBL214664 | 0.65 | SLC6A2 (0.33) | — | |
| SCHEMBL7545482 | 0.65 | SLC6A2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL27502631 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL28748183 | 0.65 | — | — | |
| SCHEMBL1053758 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102702184-A | Novel oxazolidinone derivatives | DONG A PHARM CO LTD | 2012-10-03 | — | — | CN | claimed |
| CN-102516238-A | Novel oxazolidinone derivatives | DONG A PHARM CO LTD | 2012-06-27 | — | — | CN | claimed |
| CN-1894242-A | Novel oxazolidinone derivatives | DONG A PHARM CO LTD (KR) | 2007-01-10 | — | — | CN | claimed |
| CN-107709316-A | The benzodioxan derivative of 2 (base of 1 heteroaryl piperazine 4) methyl 1,4 as α 2C antagonists | 奥赖恩公司 | 2018-02-16 | — | — | CN | disclosed |
| CN-102516238-B | Oxazolidinone derivative | 东亚ST株式会社 | 2016-08-03 | — | — | CN | disclosed |
| CN-102702184-A | Novel oxazolidinone derivatives | DONG A PHARM CO LTD | 2012-10-03 | — | — | CN | disclosed |
| CN-1894242-B | Novel oxazolidinone derivatives | DONG A PHARM CO LTD | 2012-07-04 | — | — | CN | disclosed |
| CN-102516238-A | Novel oxazolidinone derivatives | DONG A PHARM CO LTD | 2012-06-27 | — | — | CN | disclosed |
| CN-101982468-B | Novel oxazolidinone derivatives and pharmaceutical compositions comprising the derivatives | East-Asia Pharmaceutical Co., Ltd. (KR) | 2012-02-08 | — | — | CN | disclosed |
| CN-101982468-A | Novel oxazolidinone derivatives and pharmaceutical compositions comprising the derivatives | DONG A PHARM CO LTD | 2011-03-02 | — | — | CN | disclosed |
| CN-101910155-A | Be used for the treatment of biphenyl derivatives with histamine-obstacle that the H3 receptor modulators is relevant as histamine-H3 receptor modulators | ARENA PHARM INC | 2010-12-08 | — | — | CN | disclosed |
| CN-1894242-A | Novel oxazolidinone derivatives | DONG A PHARM CO LTD (KR) | 2007-01-10 | — | — | CN | disclosed |
| CN-1816534-A | Oxazolidinone antibiotics and derivatives thereof | MERCK & CO INC (US) | 2006-08-09 | — | — | CN | disclosed |
| CN-1649866-A | 3-cyclyl-5-(nitrogen-containing 5-membered ring) methyl-oxazolidinone derivatives and their use as antibacterial agents | ASTRAZENECA AB (SE) | 2005-08-03 | — | — | CN | disclosed |
| CN-1165534-C | Heterocyclyl amino methyloxazolidinones as antibacterials | — | 2004-09-08 | — | — | CN | disclosed |
| CN-1322203-A | Heterocyclic aminomethyl oxazolidinones as antibacterial agents | ASTRA ZENECA N V (SE) | 2001-11-14 | — | — | CN | disclosed |
| CN-1311787-A | oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them | ASTRA ZENECA CO LTD (SE) | 2001-09-05 | — | — | CN | disclosed |
| CN-1161968-A | Pyridine condensed thienyl- and furyl-oxazolidinone compounds | BAYER AG (DE) | 1997-10-15 | — | — | CN | disclosed |
| CN-1121919-A | 5-membered heteroaryl-oxazoli-dinones | BAYER AG (DE) | 1996-05-08 | — | — | CN | disclosed |
| CN-1119647-A | 6-membered nitrogen-containing heteroaryl-oxazolidinones | BAYER AG (DE) | 1996-04-03 | — | — | CN | disclosed |