Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Tert-Butyl Formate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27808136 | 1.00 | — | — | |
| Tert-Butyl Formate SCHEMBL30378535 | 0.96 | TDP1 (1.00) | — | |
| Tert-Butyl Formate SCHEMBL1671 | 0.96 | — | — | |
| Tert-Butyl Formate SCHEMBL28465801 | 0.93 | — | — | |
| Tert-Butyl Formate SCHEMBL27296725 | 0.93 | — | — | |
| Tert-Butyl Formate SCHEMBL27826660 | 0.93 | — | — | |
| Tert-Butyl Formate SCHEMBL9398245 | 0.93 | — | — | |
| Tert-Butyl Formate SCHEMBL15687802 | 0.93 | — | — | |
| Tert-Butyl Formate SCHEMBL4984399 | 0.93 | — | — | |
| Tert-Butyl Formate SCHEMBL28181818 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-216591060-U | Nitrogen gas supplementing device is used in production of diazaspiro-nonane-tert-butyl formate hydrochloride | 南京道尔顿化学技术有限公司 | 2022-05-24 | — | — | CN | claimed |
| CN-109053526-A | The chemical synthesis process of one kind (3R, 4S) -4- methylpyrrolidin- 3- carbamate hydrochloride | 南通大学 | 2018-12-21 | — | — | CN | claimed |
| CN-223579690-U | Nitrogen supplementing device for diazaspiro-nonane-tert-butyl formate hydrochloride production | 南京道尔顿化学技术有限公司 | 2025-11-21 | — | — | CN | disclosed |
| CN-223579690-U | Nitrogen supplementing device for diazaspiro-nonane-tert-butyl formate hydrochloride production | 南京道尔顿化学技术有限公司 | 2025-11-21 | — | — | CN | disclosed |
| CN-216591060-U | Nitrogen gas supplementing device is used in production of diazaspiro-nonane-tert-butyl formate hydrochloride | 南京道尔顿化学技术有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-216591060-U | Nitrogen gas supplementing device is used in production of diazaspiro-nonane-tert-butyl formate hydrochloride | 南京道尔顿化学技术有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-216591060-U | Nitrogen gas supplementing device is used in production of diazaspiro-nonane-tert-butyl formate hydrochloride | 南京道尔顿化学技术有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-109384803-A | ATX inhibitor and its preparation method and application | 广州市恒诺康医药科技有限公司 | 2019-02-26 | — | — | CN | disclosed |
| CN-105793251-B | Heteroaryl pyridines ketone with electrophilic functionality and azepine-pyridinone compounds | 豪夫迈·罗氏有限公司 | 2018-10-12 | — | — | CN | disclosed |
| CN-108602770-A | Novel biphenol compound or its salt | 大鹏药品工业株式会社 | 2018-09-28 | — | — | CN | disclosed |
| CN-104684915-B | Novel bicyclic derivative | 霍夫曼-拉罗奇有限公司 | 2017-10-31 | — | — | CN | disclosed |
| CN-104936950-B | The carboxamide derivative of 1H indoles 3 and its purposes as P2Y12 antagonists | 赛诺菲 | 2017-08-08 | — | — | CN | disclosed |
| CN-105793251-A | Heteroaryl pyridone and aza-pyridone compounds with electrophilic functionality | 豪夫迈·罗氏有限公司 | 2016-07-20 | — | — | CN | disclosed |
| CN-102325755-B | Substituted 5,6-dihydro-6-phenylbenzo[f] isoquinolin-2-amine compounds | ARQULE INC | 2015-07-01 | — | — | CN | disclosed |
| CN-102757422-A | Derivatives of N-[(1H-pyrazol-1-yl)aryl]-1H-indole or 1H- indazole-3-carboxamide and their therapeutic uses as p2y12 antagonists | SANOFI SA | 2012-10-31 | — | — | CN | disclosed |
| CN-102325755-A | Substituted 5,6-dihydro-6-phenyl benzo [F] isoquinoline 99.9-2-amine compound | ARQULE INC | 2012-01-18 | — | — | CN | disclosed |
| CN-101765585-A | Antibacterial agent | ACHAOGEN INC | 2010-06-30 | — | — | CN | disclosed |
| CN-1466576-A | Quinolne-(C=O)-CD1, tri-and tetrapeptide) derivatives as caspase inhibitors | øϵͳ��Ʒ��˾ | 2004-01-07 | — | — | CN | disclosed |