Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL28416794 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL11673636 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL23609 | 1.00 | — | — | |
| Pyridine SCHEMBL3706898 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL8398481 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL3801086 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL8733404 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL8398488 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL3706899 | 1.00 | — | — | |
| Pyridine SCHEMBL28848391 | 1.00 | TSHR (0.90) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 469 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991882-A | Biological gel and preparation method thereof | 连云港东朗新材料科技有限公司 | 2023-04-21 | — | — | CN | claimed |
| CN-110167932-A | Process for the preparation of (3S, 4S) -4-isopropyl-6, 7-dihydro-3H-imidazo [4, 5-c ] pyridine-5 (4H) -carboxylic acid tetrahydrofuran-3-yl ester | 博善人工智能剑桥有限公司 | 2019-08-23 | — | — | CN | claimed |
| CN-109503551-A | The preparation method of one koji Ge Lieting | 安阳师范学院 | 2019-03-22 | — | — | CN | claimed |
| CN-107429029-A | Removable film-forming gel compositions and methods of applying the same | 3M创新有限公司 | 2017-12-01 | — | — | CN | claimed |
| CN-106973904-A | Antimicrobial cloth for cleaning | 开尔弗森2200有限公司 | 2017-07-25 | — | — | CN | claimed |
| CN-105519550-A | Herbicide for coniferous nursery garden | YANTAI LONGSHUN CHEMICAL TECH CO LTD | 2016-04-27 | — | — | CN | claimed |
| CN-104496892-A | Novel technology for synthesizing 4-dimethylamino-pyridine | ANHUI COSTAR BIO CHEMICAL CO LTD | 2015-04-08 | — | — | CN | claimed |
| CN-1989115-B | Oxazole derivatives as histamine H3 receptor drugs and preparation and pharmaceutical use thereof | LILLY CO ELI | 2012-03-21 | — | — | CN | claimed |
| CN-102218067-A | Use of oxicam compounds | BINDER EVA HF | 2011-10-19 | — | — | CN | claimed |
| CN-101421267-B | Process for the preparation of pyridine heterocycle cgrp antagonist intermediate | MERCK & CO INC | 2011-10-19 | — | — | CN | claimed |
| WO-1999034793-A1 | PYRONIN ANTIBACTERIALS, PROCESS AND NOVEL INTERMEDIATES THERETO | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1999-07-15 | — | — | WO | claimed |
| EP-0311010-B1 | Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers | DU PONT MERCK PHARMA (US) | 1994-02-02 | — | — | EP | claimed |
| CN-1074908-A | Water soluble camptothecin derivatives | GLAXO INC (US) | 1993-08-04 | — | — | CN | claimed |
| CN-1072683-A | WATER SOLUBLE CAMPTOTHECIN DERIVATIVES | GLAXO INC (US) | 1993-06-02 | — | — | CN | claimed |
| US-5173489-A | α,α-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DUPONT MERCK PHARMACEUTICAL CO. (US) | 1992-12-22 | — | — | US | claimed |
| WO-1992000760-A1 | METHOD OF TREATING NEUROLOGICAL DYSFUNCTION USING NEUROTRANSMITTER ENHANCES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-01-23 | — | — | WO | claimed |
| EP-0397613-A2 | Pharmacologically active aminoimidazopyridines | DOMPE' FARMACEUTICI S.p.A. (IT) | 1990-11-14 | — | — | EP | claimed |
| EP-0311010-A2 | Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1989-04-12 | — | — | EP | claimed |
| CN-85106125-A | Prepare solid-state, the method for the quaternary dipyridinylium salt complex of weeding | — | 1986-07-02 | — | — | CN | claimed |
| EP-0000792-B1 | X-RAY IMAGE INTENSIFYING SCREENS | AGFA-GEVAERT N.V. (BE) | 1983-02-09 | — | — | EP | claimed |