Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.36 |
| ▸ | PTGS1 known ✓ | P23219 | 3/20 | 0.34 |
| ▸ | PTGS2 known ✓ | P35354 | 3/20 | 0.34 |
| ▸ | EBP | Q15125 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.34 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | GUSB | P08236 | 2/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28380881 | 1.00 | EBP (0.36) | EBPSIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL5287249 | 0.98 | EBP (0.37) | EBPSIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL4240596 | 0.98 | EBP (0.37) | EBPSIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL5293871 | 0.98 | EBP (0.37) | EBPSIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL5304234 | 0.98 | EBP (0.37) | EBPSIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL2672875 | 0.98 | EBP (0.37) | EBPSIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL1501433 | 0.98 | EBP (0.37) | EBPSIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL5288026 | 0.98 | EBP (0.37) | EBPSIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL4070942 | 0.98 | EBP (0.37) | EBPSIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL372254 | 0.98 | EBP (0.37) | EBPSIGMAR1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117586561-A | Antistatic agent composition and preparation method thereof | 杭州扬子新材料科技有限公司 | 2024-02-23 | — | — | CN | claimed |
| CN-112724107-B | Preparation method of alpha-oxo-2-furyl acetic acid and ester thereof | 南京工业大学 | 2024-01-30 | — | — | CN | claimed |
| CN-116314657-A | Graphene/tin oxide/carbon composite negative electrode material and preparation method and application thereof | 广东东岛新能源股份有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-115911541-A | Solid polymer electrolyte containing ionic liquid and preparation method thereof | 中国科学院长春应用化学研究所 | 2023-04-04 | — | — | CN | claimed |
| CN-110668535-B | Method for regenerating chemical nickel plating solution | 深圳市臻鼎环保科技有限公司 | 2022-09-09 | — | — | CN | claimed |
| CN-114618535-A | Preparation method of oxygen-enriched vacancy bimetal oxychloride nanosheet and photocatalytic CO prepared by preparation method2Reduction applications | 江苏大学 | 2022-06-14 | — | — | CN | claimed |
| CN-110863106-B | Method for extracting copper ions by ionic liquid through aqueous two-phase extraction | 江南大学 | 2021-07-27 | — | — | CN | claimed |
| CN-112724107-A | Preparation method of alpha-oxo-2-furyl acetic acid and ester thereof | 南京工业大学 | 2021-04-30 | — | — | CN | claimed |
| CN-110863106-A | Method for extracting copper ions by ionic liquid through aqueous two-phase extraction | 江南大学 | 2020-03-06 | — | — | CN | claimed |
| CN-110668535-A | Method for regenerating chemical nickel plating solution | 深圳市臻鼎环保科技有限公司 | 2020-01-10 | — | — | CN | claimed |
| CN-117586561-A | Antistatic agent composition and preparation method thereof | 杭州扬子新材料科技有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-117586561-A | Antistatic agent composition and preparation method thereof | 杭州扬子新材料科技有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-112724107-B | Preparation method of alpha-oxo-2-furyl acetic acid and ester thereof | 南京工业大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-116375443-B | Composite material for self-repairing bridge cracks and preparation method thereof | 江苏五茅建设集团有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-116375443-A | Composite material for self-repairing bridge cracks and preparation method thereof | 江苏五茅建设集团有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-111100249-A | Single-ion polymer electrolyte, preparation method thereof and lithium ion battery | 比亚迪股份有限公司 | 2020-05-05 | — | — | CN | disclosed |
| CN-111106381-A | Polymer electrolyte, preparation method thereof and lithium ion battery | 深圳市比亚迪锂电池有限公司 | 2020-05-05 | — | — | CN | disclosed |
| CN-110943249-A | Polymer electrolyte and lithium ion battery | 深圳市比亚迪锂电池有限公司 | 2020-03-31 | — | — | CN | disclosed |
| CN-110863106-A | Method for extracting copper ions by ionic liquid through aqueous two-phase extraction | 江南大学 | 2020-03-06 | — | — | CN | disclosed |
| CN-110668535-A | Method for regenerating chemical nickel plating solution | 深圳市臻鼎环保科技有限公司 | 2020-01-10 | — | — | CN | disclosed |