Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 4/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.85 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.85 |
| ▸ | RECQL | P46063 | 3/20 | 0.85 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.85 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.85 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.85 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.85 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.85 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29366607 | 0.92 | THRB (1.00) | THRBCYP3A4MAPK1RECQLHSD17B10 | |
| SCHEMBL29568770 | 0.91 | THRB (0.86) | THRBCYP3A4MAPK1RECQLHSD17B10 | |
| SCHEMBL29482552 | 0.80 | ALDH1A1 (0.78) | THRBCYP3A4MAPK1RECQLHSD17B10 | |
| SCHEMBL29390387 | 0.79 | MAPK1 (0.77) | THRBCYP3A4MAPK1RECQLHSD17B10 | |
| SCHEMBL29438532 | 0.76 | APP (0.66) | THRBCYP3A4MAPK1RECQLHSD17B10 | |
| SCHEMBL185277 | 0.73 | APP (0.98) | THRBCYP3A4MAPK1RECQLHSD17B10 | |
| SCHEMBL29637814 | 0.73 | MEN1 (0.64) | THRBCYP3A4MAPK1RECQLHSD17B10 | |
| Orange G SCHEMBL29369740 | 0.72 | APP (1.00) | THRBCYP3A4MAPK1RECQLHSD17B10 | |
| Orange G SCHEMBL81967 | 0.72 | APP (1.00) | THRBCYP3A4MAPK1RECQLHSD17B10 | |
| Orange G SCHEMBL3873344 | 0.72 | APP (1.00) | THRBCYP3A4MAPK1RECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025014926-A1 | COMPOSITIONS AND METHODS FOR PERMANENTLY OR REVERSIBLY COLORING FIBERS AND TEXTILES | TANDEM REPEAT TECHNOLOGIES, INC. (US) | 2025-01-16 | — | — | WO | disclosed |
| US-20240077489-A1 | STYRYL PHENOLS, DERIVATIVES AND THEIR USE IN METHODS OF ANALYTE DETECTION | AAT BIOQUEST, INC. | 2024-03-07 | — | — | US | disclosed |
| US-11821901-B2 | Styryl phenols, derivatives and their use in methods of analyte detection | AAT BIOQUEST, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| CN-111133382-B | Photosensitive resin composition, cured film, element and organic EL display device having cured film, and method for producing same | 东丽株式会社 | 2023-10-31 | — | — | CN | disclosed |
| CN-111094474-B | Near-infrared-curable ink composition, near-infrared-curable film, method for producing near-infrared-curable film, and method for photo-molding | 住友金属矿山株式会社 | 2022-06-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11821901-B2 | Styryl phenols, derivatives and their use in methods of analyte detection | STUB1, SPR, HLCS | THRB 309/4885CYP3A4 314/4885MAPK1 4195/4885 |
| US-20240077489-A1 | STYRYL PHENOLS, DERIVATIVES AND THEIR USE IN METHODS OF ANALYTE DETECTION | STUB1, SPR, HLCS | THRB 309/4885CYP3A4 314/4885MAPK1 4195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.