Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Nonane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.89 |
| ▸ | THRB | P10828 | 1/20 | 0.89 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecane SCHEMBL3040512 | 1.00 | TSHR (0.89) | TSHRTHRBDNM1LMNAALDH1A1 | |
| Hexadecane SCHEMBL5510405 | 1.00 | TSHR (0.89) | TSHRTHRBDNM1LMNAALDH1A1 | |
| Octane SCHEMBL8645563 | 1.00 | TSHR (0.89) | TSHRTHRBDNM1LMNAALDH1A1 | |
| Octane SCHEMBL9775406 | 1.00 | TSHR (0.89) | TSHRTHRBDNM1LMNAALDH1A1 | |
| Decane SCHEMBL10448068 | 1.00 | TSHR (0.89) | TSHRTHRBDNM1LMNAALDH1A1 | |
| Nonane SCHEMBL3814127 | 1.00 | TSHR (0.89) | TSHRTHRBDNM1LMNAALDH1A1 | |
| Decane SCHEMBL7183338 | 1.00 | TSHR (0.89) | TSHRTHRBDNM1LMNAALDH1A1 | |
| Octane SCHEMBL8167210 | 1.00 | TSHR (0.89) | TSHRTHRBDNM1LMNAALDH1A1 | |
| Heptane SCHEMBL694283 | 1.00 | — | — | |
| Heptane SCHEMBL3638943 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025002452-A1 | LIQUID ORGANIC COMPOSITION FOR LITHIUM EXTRACTION, AND PREPARATION METHOD THEREFOR | 北京索特莱克科技发展有限公司 | 2025-01-02 | — | — | WO | claimed |
| CN-118080011-A | Catalyst for preparing methanol by hydrogenation of carbon dioxide, preparation method and application thereof | 国家能源集团新能源技术研究院有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-115417850-B | Application of catalyst containing spiro-cyclic compound in catalyzing reaction of epoxy compound and carbon dioxide | 深圳新宙邦科技股份有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-115417850-A | Application of catalyst containing spiro-cyclic compound in catalyzing reaction of epoxy compound and carbon dioxide | 深圳新宙邦科技股份有限公司 | 2022-12-02 | — | — | CN | claimed |
| CN-211800670-U | Granulator is used in production of nonane hydrochloride | 长兴中昊化工有限公司 | 2020-10-30 | — | — | CN | claimed |
| CN-210719363-U | Weighing device is used in production of heterocyclononane hydrochloride | 沙洋秦江化工有限公司 | 2020-06-09 | — | — | CN | claimed |
| CN-210619105-U | Storage device is used in production of heterocyclononane hydrochloride | 沙洋秦江化工有限公司 | 2020-05-26 | — | — | CN | claimed |
| CN-210592519-U | A packing apparatus for hetercyclononane hydrochloride | 沙洋秦江化工有限公司 | 2020-05-22 | — | — | CN | claimed |
| CN-102784149-B | 5-aryl-9-alkyl-4,6-dioxo-1-aza-bicyclo[3.3.1]nonane and application of salt thereof | UNIV HUNAN | 2013-08-28 | — | — | CN | claimed |
| CN-102784149-A | 5-aryl-9-alkyl-4,6-dioxo-1-aza-bicyclo[3.3.1]nonane and application of salt thereof | UNIV HUNAN | 2012-11-21 | — | — | CN | claimed |
| CN-101418003-B | 5-aryl-9-alkyl-4,6-dioxo-1-aza-bicyclo[3.3.1]nonane hydrochloride and preparation method thereof | UNIV HUNAN | 2012-01-25 | — | — | CN | claimed |
| CN-101910170-A | (1,4-diazabicyclo [3.2.2] ninth of the ten Heavenly Stems-6-alkene-4-yl)-heterocyclic radical-ketone part that is used for the treatment of the nicotinic acetylcholine receptor of disease | MEMORY PHARM CORP | 2010-12-08 | — | — | CN | claimed |
| CN-101418003-A | 5-aryl-9-alkyl-4,6-dioxo-1-aza-bicyclo[3.3.1]nonane hydrochloride and preparation method thereof | UNIV HUNAN (CN) | 2009-04-29 | — | — | CN | claimed |
| US-20250066359-A1 | SOMATOSTATIN RECEPTOR SUBTYPE 5 ANTAGONISTS, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2025-02-27 | — | — | US | disclosed |
| WO-2025002452-A1 | LIQUID ORGANIC COMPOSITION FOR LITHIUM EXTRACTION, AND PREPARATION METHOD THEREFOR | 北京索特莱克科技发展有限公司 | 2025-01-02 | — | — | WO | disclosed |
| WO-2024140690-A1 | INTERMEDIATES OF SONROTOCLAX AND THE METHOD OF PREPARING THE SAME | BEIGENE (SUZHOU) CO., LTD. (CN) | 2024-07-04 | — | — | WO | disclosed |
| EP-0001644-A1 | N-substituted mercaptoacetamidines and pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1979-05-02 | — | — | EP | disclosed |
| US-4144271-A | IMMUNOREGULANTS | MERCK & CO., INC. (US) | 1979-03-13 | — | — | US | disclosed |
| US-4087550-A | Hydroxylated amine thioethers for improving the greasy and unaesthetic appearance of the hair and skin | L'OREAL (FR) | 1978-05-02 | — | — | US | disclosed |
| US-3968218-A | Cosmetic composition containing a hydroxylated amino thioether for application to the hair and skin | L'OREAL (FR) | 1976-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066359-A1 | SOMATOSTATIN RECEPTOR SUBTYPE 5 ANTAGONISTS, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | SSTR5, SSTR2, SSTR3 | TSHR 40/4885THRB 99/4885DNM1 4250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.