Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Dioxane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dioxane SCHEMBL19124170 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL31664298 | 1.00 | TTR (0.86) | — | |
| Dioxane SCHEMBL25293907 | 1.00 | TTR (0.86) | — | |
| Dioxane SCHEMBL23466883 | 1.00 | TTR (0.86) | — | |
| Dioxane SCHEMBL28467529 | 0.94 | — | — | |
| Dioxane SCHEMBL28825140 | 0.94 | — | — | |
| Dioxane SCHEMBL1227663 | 0.94 | — | — | |
| Dioxane SCHEMBL6954886 | 0.94 | — | — | |
| Oxirane SCHEMBL9903963 | 0.93 | — | — | |
| Oxirane SCHEMBL4815843 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 13663 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121248582-B | CDK12/PARP double-target inhibitor and preparation method and application thereof | SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) | 2026-05-26 | — | — | CN | claimed |
| US-12637469-B2 | 1H-pyrazole derivative and application thereof as dual target inhibitor of Syk and VEGFR2 | OCUMENSION THERAPEUTICS (SUZHOU) CO., LTD. (CN) | 2026-05-26 | — | — | US | claimed |
| CN-122071449-A | Substituted biphenyl compounds and application thereof in synthesis of cola pyrroside | 北京凯因格领生物技术有限公司 | 2026-05-22 | — | — | CN | claimed |
| EP-3797103-B1 | A NOVEL PROCESS FOR THE PREPARATION OF ANTHRANILIC DIAMIDES | PI INDUSTRIES LTD (IN) | 2026-04-08 | — | — | EP | claimed |
| EP-4712957-A2 | ISOANDROGRAPHOLIDE ANALOGS AND METHOD FOR TREATMENT USING THE SAME | Enveda Therapeutics, Inc. (US) | 2026-03-25 | — | — | EP | claimed |
| CN-119606872-B | Multifunctional hydrogel and application thereof | 山东第二医科大学 | 2025-06-13 | — | — | CN | claimed |
| CN-115960346-B | Amphiphilic polymer with retinol derivative as hydrophobic chain | 中国药科大学 | 2025-05-27 | — | — | CN | claimed |
| CN-120004919-A | Synthesis method and application of N-heterocyclic carbene compound based on functionalized porphyrin | 西北大学 | 2025-05-16 | — | — | CN | claimed |
| CN-119954866-A | Pentafluoroalkoxy ring preparation method of triphosphazene | 安徽金禾合成材料研究院有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-119930591-A | STING degradation agent with nitrogenous ring derivative as Linker, and synthetic method and application thereof | 海南大学 | 2025-05-06 | — | — | CN | claimed |
| US-7163917-B2 | Synthesis method of alanylglutamine | ZHAO YUFEN | 2007-01-16 | — | — | US | claimed |
| US-20050233977-A1 | Process of producing ala-gln dipeptide | ZHAO YUFEN | 2005-10-20 | — | — | US | claimed |
| CN-1467220-A | Tripeptide analogs, preparation method thereof, pharmaceutical compositions containing the same and application thereof | 中国人民解放军军事医学科学院毒物药 | 2004-01-14 | — | — | CN | claimed |
| CN-1467219-A | Pentapeptide analogues, their preparation and their use | 中国人民解放军军事医学科学院毒物药 | 2004-01-14 | — | — | CN | claimed |
| EP-0376870-A1 | A new organosilylpolyphosphoric reagent, its preparation and application to the process of synthesis of 3-carboxyquinolones or azaquinolones and their salts | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1990-07-04 | — | — | EP | claimed |
| EP-0356366-A1 | A process for the preparation of N-sulfamyl-propionamidine derivatives | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1990-02-28 | — | — | EP | claimed |
| EP-0126942-B1 | PREPARATION PROCESS OF ACEMETACIN | Troponwerke GmbH & Co. KG (DE) | 1987-09-30 | — | — | EP | claimed |
| US-4603210-A | Preparation process of acemetacin | TROPONWERKE GMBH & CO. KG. (DE) | 1986-07-29 | — | — | US | claimed |
| EP-0126942-A1 | Preparation process of acemetacin | Troponwerke GmbH & Co. KG (DE) | 1984-12-05 | — | — | EP | claimed |
| US-4330466-A | Process for the production of cholecystokinin-pancreozymin C-terminal peptide amide sulfate esters | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1982-05-18 | — | — | US | claimed |