Thiourea

Thiourea

SCHEMBL316387

Cl.NC(N)=S

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Thiourea. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiourea SCHEMBL28326148 1.00
Thiourea SCHEMBL29265639 0.94
Thiourea SCHEMBL4268552 0.94 TSHR (0.75)
Thiourea SCHEMBL27527222 0.94
Thiourea SCHEMBL2374292 0.94
Thiourea SCHEMBL28912909 0.94
Thiourea SCHEMBL1719801 0.94
Thiourea SCHEMBL31425705 0.94
Thiourea SCHEMBL4933728 0.94
Thiourea SCHEMBL7593783 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112897621-B Extraction and recovery of palladium from aqueous solutions LCW超临界技术公司 2024-12-13 CN claimed
CN-118419927-B Preparation method of biomass porous carbon for super capacitor and super capacitor 福建省鑫森炭业股份有限公司 2024-12-03 CN claimed
CN-118419927-A Preparation method of biomass porous carbon for super capacitor and super capacitor 福建省鑫森炭业股份有限公司 2024-08-02 CN claimed
CN-118324723-A Synthesis method of 2-methyl-3-tetrahydrofuranthiol 滕州市天水生物科技有限公司 2024-07-12 CN claimed
CN-117924265-B Synthesis method of pyrifos 潍坊新绿化工有限公司 2024-06-18 CN claimed
CN-117986198-A Preparation method of herbicide intermediate 帕潘纳(北京)科技有限公司 2024-05-07 CN claimed
WO-2024088280-A1 PREPARATION METHOD FOR HERBICIDE INTERMEDIATE 帕潘纳(北京)科技有限公司 2024-05-02 WO claimed
CN-117568805-A CO inhibition 2 Corrosion inhibitor for corrosion and preparation method and application thereof 西安石油大学 2024-02-20 CN claimed
CN-113403478-B Method for separating metal from electronic waste based on nano carbon material 苏州市富荣环保科技有限公司 2024-01-26 CN claimed
US-11718539-B2 Extraction and recovery of Pd from aqueous solutions LCW SUPERCRITICAL TECH CORPORATION (US) 2023-08-08 US claimed
CN-108571018-A A kind of underground waterproof engineering construction method using self-adhesive waterproof material containing gallium 于连正 2018-09-25 CN claimed
CN-108545711-A A kind of electronic grade high-purity phosphoric acid synthesis device of terbium Sb doped material preparation 王立国 2018-09-18 CN claimed
CN-106785081-A A kind of battery liquid and its battery 叶晓东 2017-05-31 CN claimed
CN-105819595-A Method for recycling gold in situ from gold-containing wastewater 深圳市世清环保科技有限公司 2016-08-03 CN claimed
CN-104903309-A 1,2,3-triazole-4-amine derivatives for treatment of sigma receptor related diseases and disorders ESTEVE LABOR DR 2015-09-09 CN claimed
CN-102778451-A Method for measuring contents of gold, silver and palladium in crude copper SHANGHAI GEM HIGH TECH CO LTD 2012-11-14 CN claimed
US-7420062-B2 Hetaryl-substituted pyrazolidindione derivatives with pesticidal characteristics BAYER CROPSCIENCE, AG (DE) 2008-09-02 US claimed
US-20070066488-A1 Hetaryl-substituted pyrazolidindione derivatives with pesticidal characteristics BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-03-22 US claimed
US-3963730-A ACID CATALYST SANKYO COMPANY LIMITED (JA) 1976-06-15 US claimed
US-3953459-A Process for the preparation of 2,2,6,6-tetramethyl-4-oxopiperidine CIBA-GEIGY CORPORATION (US) 1976-04-27 US claimed