Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7184849 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL6869427 | 0.80 | — | — | |
| SCHEMBL27815551 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL7109535 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL6130328 | 0.80 | — | — | |
| Bromide SCHEMBL17629058 | 0.80 | — | — | |
| SCHEMBL412138 | 0.78 | — | — | |
| SCHEMBL11620153 | 0.67 | — | — | |
| Water SCHEMBL3477607 | 0.67 | — | — | |
| SCHEMBL5720449 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2015722-B1 | ANTIMICROBIAL SITE DRESSINGS | AVENT INC (US) | 2016-11-16 | — | — | EP | disclosed |
| US-8293965-B2 | Antimicrobial site dressings | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2012-10-23 | — | — | US | disclosed |
| US-8203029-B2 | Silver-containing compositions, devices and methods for making | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2012-06-19 | — | — | US | disclosed |
| US-20100034882-A1 | SILVER-CONTAINING COMPOSITIONS, DEVICES AND METHODS FOR MAKING | AVANOS MEDICAL SALES, LLC | 2010-02-11 | — | — | US | disclosed |
| US-7576255-B2 | Silver-containing compositions, devices, and methods for making | ACRYMED, INC. (US) | 2009-08-18 | — | — | US | disclosed |
| EP-2015722-A2 | ANTIMICROBIAL SITE DRESSINGS | ACRYMED, INC. (US) | 2009-01-21 | — | — | EP | disclosed |
| EP-1216065-B1 | SILVER-CONTAINING COMPOSITIONS, DEVICES AND METHODS FOR MAKING | ACRYMED (US) | 2008-10-29 | — | — | EP | disclosed |
| US-20070293800-A1 | Antimicrobial site dressings | AVANOS MEDICAL SALES, LLC | 2007-12-20 | — | — | US | disclosed |
| WO-2007127236-A2 | ANTIMICROBIAL SITE DRESSINGS | ACRYMED, INC. (US) | 2007-11-08 | — | — | WO | disclosed |
| US-20050226931-A1 | Stabilized silver antimicrobial devices comprising a matrix comprising a polymer network and a non-gellable polysaccharide, and an active agent; wound treatment | ACRYMED, INC. (US) | 2005-10-13 | — | — | US | disclosed |
| US-6897349-B2 | Silver-containing compositions, devices and methods for making | ACRYMED (US) | 2005-05-24 | — | — | US | disclosed |
| US-20040010215-A1 | Silver-containing compositions, devices and methods for making | Virchow Biotech Pvt Ltd (IN) | 2004-01-15 | — | — | US | disclosed |
| US-6605751-B1 | Metal colloid is directly incorporated in polymer matrix without the prior incorporation of the metal colloid into another delivery vehicle | ACRYMED | 2003-08-12 | — | — | US | disclosed |
| WO-2001024839-A9 | SILVER-CONTAINING COMPOSITIONS, DEVICES AND METHODS FOR MAKING | ACRYMED (US) | 2002-11-14 | — | — | WO | disclosed |