Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9106048 | 0.98 | CES1 (0.36) | CES1MEN1ALDH1A1LMNAHPGD | |
| SCHEMBL9105169 | 0.98 | CES1 (0.36) | CES1MEN1ALDH1A1LMNAHPGD | |
| SCHEMBL9107685 | 0.98 | CES1 (0.36) | CES1MEN1ALDH1A1LMNAHPGD | |
| SCHEMBL10021591 | 0.88 | CES1 (0.37) | CES1MEN1ALDH1A1LMNAHPGD | |
| SCHEMBL342250 | 0.82 | THRB (0.37) | CES1MEN1ALDH1A1LMNAHPGD | |
| SCHEMBL30702588 | 0.80 | KDM4E (0.40) | CES1MEN1ALDH1A1LMNAHPGD | |
| SCHEMBL11968417 | 0.80 | KDM4E (0.40) | CES1MEN1ALDH1A1LMNAHPGD | |
| SCHEMBL11876684 | 0.80 | KDM4E (0.40) | CES1MEN1ALDH1A1LMNAHPGD | |
| SCHEMBL342150 | 0.78 | — | — | |
| SCHEMBL2861511 | 0.76 | MAPT (0.39) | CES1MEN1ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250108658-A1 | INKJET PRINTING PROCESSES FOR TEMPORARY TATTOOS | Prism Inks, Inc. (US) | 2025-04-03 | — | — | US | disclosed |
| EP-3691751-B1 | DUAL POLYMER COMPONENT HAIR COLORING COMPOSITION | WELLA OPERATIONS US LLC (US) | 2024-02-14 | — | — | EP | disclosed |
| US-20230310300-A1 | HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER | HFC PRESTIGE SERVICE GERMINY GMBH (DE) | 2023-10-05 | — | — | US | disclosed |
| EP-4171500-A1 | HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER | Wella Germany GmbH (DE) | 2023-05-03 | — | — | EP | disclosed |
| WO-2022188373-A1 | METHOD FOR DETECTING WATER-SOLUBLE ANIONIC SYNTHETIC PIGMENT IN FOOD | 广州市食品检验所（广州市酒类检测中心） | 2022-09-15 | — | — | WO | disclosed |
| EP-2710996-B1 | Sunscreen compositions comprising colour pigments | BASF SE (DE) | 2022-08-17 | — | — | EP | disclosed |
| US-11384033-B2 | Compositions with improved urease-inhibiting effect comprising (thio)phosphoric acid triamide and further compounds such as amines and colorants | BASF SE (DE) | 2022-07-12 | — | — | US | disclosed |
| US-11324688-B2 | Bicomponent composition | WELLA INTERNATIONAL OPERATIONS SWI (CH) | 2022-05-10 | — | — | US | disclosed |
| US-20220054392-A1 | MULTICOMPONENT IN SITU COLORATION COMPOSITION | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2022-02-24 | — | — | US | disclosed |
| US-20220016017-A1 | COLOR COATINGS WITH DOWNSTREAM FEATURES | HFC PRESTIGE SERVICE GERMANY GMBH (DE) | 2022-01-20 | — | — | US | disclosed |
| EP-3237360-A1 | COMPOSITIONS WITH IMPROVED UREASE-INHIBITING EFFECT COMPRISING (THIO) PHOSPHORIC ACID TRIAMIDE AND FURTHER COMPOUNDS SUCH AS AMINES AND COLORANTS | BASF SE (DE) | 2017-11-01 | — | — | EP | disclosed |
| US-20170231889-A1 | Sunscreen Compositions Comprising Colour Pigments | BASF SE (DE) | 2017-08-17 | — | — | US | disclosed |
| WO-2016103168-A1 | COMPOSITIONS WITH IMPROVED UREASE-INHIBITING EFFECT COMPRISING (THIO) PHOSPHORIC ACID TRIAMIDE AND FURTHER COMPOUNDS SUCH AS AMINES AND COLORANTS | BASF SE (DE) | 2016-06-30 | — | — | WO | disclosed |
| EP-2710996-A2 | Sunscreen compositions comprising colour pigments | BASF SE (DE) | 2014-03-26 | — | — | EP | disclosed |
| US-8268014-B2 | Hair dyeing composition | BASF SE Ludwigshafen (DE) | 2012-09-18 | — | — | US | disclosed |
| US-8257448-B2 | Hair dyeing composition | BASF SE (DE) | 2012-09-04 | — | — | US | disclosed |
| US-20120141398-A1 | HAIR DYE CONTAINING ONE OR MORE EDIBLE OR COSMETIC COLORS | CHUANG KUO SHENG (TW) | 2012-06-07 | — | — | US | disclosed |
| US-20120017931-A1 | HAIR DYEING COMPOSITION | BASF SE (DE) | 2012-01-26 | — | — | US | disclosed |
| US-20120012128-A1 | HAIR DYEING COMPOSITION | BASF SE (DE) | 2012-01-19 | — | — | US | disclosed |
| US-20110033400-A1 | SUNSCREEN COMPOSITIONS COMPRISING COLOUR PIGMENTS | BASF SE (US) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120012128-A1 | HAIR DYEING COMPOSITION | CYC1, CYB5R3, TYR | THRB 3510/4885CES1 1648/4885MEN1 1913/4885 |
| US-20110033400-A1 | SUNSCREEN COMPOSITIONS COMPRISING COLOUR PIGMENTS | TYR, ERCC1, ERCC4 | THRB 4299/4885CES1 2439/4885MEN1 1447/4885 |
| US-20220016017-A1 | COLOR COATINGS WITH DOWNSTREAM FEATURES | KRT18, ITGA5, FLNA | THRB 3175/4885CES1 4636/4885MEN1 2431/4885 |
| US-20230310300-A1 | HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER | KRT18, MKI67, IK | THRB 2221/4885CES1 4520/4885MEN1 811/4885 |
| US-20120017931-A1 | HAIR DYEING COMPOSITION | CYB5R3, CYC1, CYCS | THRB 2777/4885CES1 2032/4885MEN1 2016/4885 |
| US-20220054392-A1 | MULTICOMPONENT IN SITU COLORATION COMPOSITION | KRT18, PRKDC, VIM | THRB 3076/4885CES1 4013/4885MEN1 1309/4885 |
| US-11324688-B2 | Bicomponent composition | KRT18, EXOSC10, EXOSC9 | THRB 3674/4885CES1 4881/4885MEN1 1869/4885 |
| US-11384033-B2 | Compositions with improved urease-inhibiting effect comprising (thio)phosphoric acid triamide and further compounds such as amines and colorants | SLC14A1, XDH, PNP | THRB 972/4885CES1 407/4885MEN1 4263/4885 |
| US-20170231889-A1 | Sunscreen Compositions Comprising Colour Pigments | TYR, ERCC1, ERCC4 | THRB 4299/4885CES1 2439/4885MEN1 1447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.