SCHEMBL345325

SCHEMBL345325

CCCCCCON(CC)CC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 1/20 0.46
BLM P54132 1/20 0.46
GPR84 Q9NQS5 7/20 0.42
PPARG P37231 7/20 0.42
PPARD Q03181 7/20 0.42
PPARA Q07869 7/20 0.42
HDAC11 Q96DB2 5/20 0.42
TSHR P16473 4/20 0.42
PTPN1 P18031 3/20 0.42
ALDH1A1 P00352 2/20 0.42
TLR2 O60603 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
FABP4 P15090 2/20 0.42
SLC22A6 Q4U2R8 1/20 0.42
SLC22A8 Q8TCC7 1/20 0.42
MEN1 O00255 1/20 0.42
ESR1 P03372 1/20 0.42
ALOX15 P16050 1/20 0.42
PDE4A P27815 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10171416 0.92 PLA2G2A (0.49) PLA2G2ABLMGPR84PPARGPPARD
SCHEMBL8198217 0.86 GPR84 (0.48) PLA2G2ABLMGPR84PPARGPPARD
SCHEMBL8525433 0.86 GPR84 (0.48) PLA2G2ABLMGPR84PPARGPPARD
SCHEMBL7717708 0.84 BLM (0.37) PLA2G2ABLMTSHRTDP1ALOX15
SCHEMBL3045373 0.80 THRB (0.42) TSHRALDH1A1MEN1KMT2ANAAA
SCHEMBL8574590 0.77 THRB (0.37) TSHRALDH1A1MEN1KMT2ANAAA
SCHEMBL10171287 0.76 BLM (0.37) PLA2G2ABLMGPR84PPARGPPARD
SCHEMBL4810103 0.74 DNM1 (0.37) TSHRALDH1A1MEN1KMT2ANAAA
SCHEMBL28126402 0.74 DNM1 (0.42) TSHRALDH1A1MEN1KMT2ANAAA
SCHEMBL4765473 0.74 TSHR (0.41) PLA2G2ABLMGPR84TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1888491-B1 ISOALKANE MIXTURE, ITS PREPARATION AND USE BASF SE (DE) 2017-03-01 EP disclosed
US-9084734-B2 Peptide personal care compositions and methods for their use DANISCO US INC. (US) 2015-07-21 US disclosed
US-8962796-B2 Modified variant Bowman Birk protease inhibitors DANISCO US INC. (US) 2015-02-24 US disclosed
US-8821842-B2 Isoalkane mixture, its preparation and use BASF SE (DE) 2014-09-02 US disclosed
US-20130195781-A1 Modified Variant Bowman Birk Protease Inhibitors DANISCO US INC. (US) 2013-08-01 US disclosed
US-8394941-B2 Modified variant Bowman Birk Protease Inhibitors DANISCO US INC. (US) 2013-03-12 US disclosed
US-20120014885-A1 Personal Care Compositions and Methods for Their Use DANISCO US INC. 2012-01-19 US disclosed
CN-1960699-B Keratin binding polypeptides BASF AG (DE) 2011-12-28 CN disclosed
US-20110256608-A1 Modified Variant Bowman Birk Protease Inhibitors DANISCO US INC. (US) 2011-10-20 US disclosed
CN-101278051-B Personal care compositions and methods of use thereof GENENCOR INT 2011-10-05 CN disclosed
CN-101278051-A Personal care compositions and methods of use thereof GENENCOR INT (US) 2008-10-01 CN disclosed
US-20080199420-A1 Cosmetic oil in water emulsion ofamphiphilic polymer with hydrophilic and hydrophobic units formed from polyisobutenes modified with terminal polar groups, emulsifier, oil and water; ethylene oxide-propylene oxide block polymer modified polyisobutenyl succinic anhydride; hydroxylation, epoxidation BASF AKTIENGESELLSCHAFT (DE) 2008-08-21 US disclosed
US-20080194708-A1 Cationic Polymers as Thickeners for Aqueous and Alcoholic Compositions BASF AKTIENGESELLSCHAFT (DE) 2008-08-14 US disclosed
US-20080194715-A1 Use of Copolymers Comprising Polyisobutene in Cosmetic Compositions BASF AKTIENGESELLSCHAFT (DE) 2008-08-14 US disclosed
US-20080193404-A1 Cosmetic; free from intrinsic odors and have an extremely wide liquid interval; heat transfer liquid; fuel additives and low-temperature fuel; shock absorber oil BASF AKTIENGESELLSCHAFT (DE) 2008-08-14 US disclosed
US-20080193405-A1 Use of a Water-In-Water Emulsion Polymers in the Form of a Thickener for Cosmetic Preparations BASF AKTIENGESELLSCHAFT (DE) 2008-08-14 US disclosed
CN-101193841-A Isoalkane mixtures, their preparation and use BASF AG (DE) 2008-06-04 CN disclosed
US-20080075684-A1 Keratin-Binding Polypeptides BASF AKTIENGESELLSCHAFT (DE) 2008-03-27 US disclosed
CN-101151016-A Use of a water-in-water emulsion polymers in the form of a thickener for cosmetic preparations BASF AG (DE) 2008-03-26 CN disclosed
CN-1960699-A Keratin binding polypeptides BASF AG (DE) 2007-05-09 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194708-A1 Cationic Polymers as Thickeners for Aqueous and Alcoholic Compositions ADH1A, ADH1C, PCNA PLA2G2A 718/4885BLM 2398/4885GPR84 2082/4885
US-20080199420-A1 Cosmetic oil in water emulsion ofamphiphilic polymer with hydrophilic and hydrophobic units formed from polyisobutenes modified with terminal polar groups, emulsifier, oil and water; ethylene oxide-propylene oxide block polymer modified polyisobutenyl succinic anhydride; hydroxylation, epoxidation HAO2, LRBA, POLB PLA2G2A 2019/4885BLM 3588/4885GPR84 868/4885
US-20080193404-A1 Cosmetic; free from intrinsic odors and have an extremely wide liquid interval; heat transfer liquid; fuel additives and low-temperature fuel; shock absorber oil CUTA, TRPA1, FDFT1 PLA2G2A 2659/4885BLM 2109/4885GPR84 1214/4885
US-20120014885-A1 Personal Care Compositions and Methods for Their Use CUTA, VEGFA, BDNF PLA2G2A 3006/4885BLM 1878/4885GPR84 321/4885
US-20130195781-A1 Modified Variant Bowman Birk Protease Inhibitors SERPINB1, BBC3, BRAP PLA2G2A 2267/4885BLM 647/4885GPR84 4151/4885
US-20080193405-A1 Use of a Water-In-Water Emulsion Polymers in the Form of a Thickener for Cosmetic Preparations POLH, POLR1C, POLQ PLA2G2A 1534/4885BLM 1152/4885GPR84 2503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.