Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Propene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propene SCHEMBL10494774 | 1.00 | — | — | |
| Propene SCHEMBL28337196 | 0.94 | TSHR (0.31) | — | |
| Propene SCHEMBL49990 | 0.94 | — | — | |
| Propene SCHEMBL28018192 | 0.94 | TSHR (0.31) | — | |
| Propene SCHEMBL11497879 | 0.94 | — | — | |
| Propene SCHEMBL27283141 | 0.94 | — | — | |
| Propene SCHEMBL10768025 | 0.94 | — | — | |
| Propene SCHEMBL6495449 | 0.94 | — | — | |
| Propene SCHEMBL11498542 | 0.94 | — | — | |
| Propene SCHEMBL476626 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115777002-B | Polyethylene pipe resin with high resistance to slow crack growth | 博里利斯股份公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-116670223-A | Polyolefin pipe resins with very good sag resistance and slow crack growth | 博里利斯股份公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-114874373-B | Liquid butyl rubber and preparation method thereof | 中国石油化工股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-114874371-B | Method for preparing liquid butyl rubber and liquid butyl rubber prepared by same | 中国石油化工股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-114874372-B | Liquid butyl rubber and method for preparing liquid butyl rubber | 中国石油化工股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-112654649-B | Process for producing heterophasic propylene copolymers with high xylene cold soluble fraction (XCS) | 博里利斯股份公司 | 2023-04-14 | — | — | CN | disclosed |
| US-11370850-B2 | Polymerization compositions and methods for making and using same | PRETIUM INNOVATION, LLC (US) | 2022-06-28 | — | — | US | disclosed |
| WO-2020226890-A1 | POLYMERIZATION COMPOSITIONS AND METHODS FOR MAKING AND USING SAME | HANIK PETER (US) | 2020-11-12 | — | — | WO | disclosed |
| CN-110741039-A | Polypropylene composition | 博里利斯股份公司 | 2020-01-31 | — | — | CN | disclosed |
| EP-2463315-B1 | Process for preparing a multimodal polyolefin employing a Ziegler-Natta catalyst | BOREALIS TECH OY (FI) | 2018-01-03 | — | — | EP | disclosed |
| EP-0423861-A2 | Process for the preparation of ethylene-butene-1 copolymers having an ultralow density | ENICHEM S.p.A. (IT) | 1991-04-24 | — | — | EP | disclosed |
| EP-0421525-A2 | Process for the preparation of ethylene-propylene copolymers | ENICHEM S.p.A. (IT) | 1991-04-10 | — | — | EP | disclosed |
| US-4329256-A | Process for the manufacture of a mixed catalyst | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-05-11 | — | — | US | disclosed |
| US-4272404-A | ENTANGLED IN POLYTETRAFLUOROETHYLENE WEB | EXXON RESEARCH AND ENGINEERING COMPANY | 1981-06-09 | — | — | US | disclosed |
| US-4272405-A | INCREASING PARTICLE SIZE BY ENTANGLING IN A WEB OF POLYTETRAFLUOROETHYLENE | EXXON RESEARCH AND ENGINEERING COMPANY | 1981-06-09 | — | — | US | disclosed |
| US-4175170-A | COORDINATION CATALYSTS, POLYMERIZATION CATALYSTS | BASF AKTIENGESELLSCHAFT (DE) | 1979-11-20 | — | — | US | disclosed |
| US-4008176-A | ORGANO-TITANIUM-ALUMINUM HALIDE POLYMERIZATION | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-02-15 | — | — | US | disclosed |
| US-4008177-A | Process for the manufacture of a catalyst | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-02-15 | — | — | US | disclosed |
| US-4007133-A | FROM TITANIUM TETRACHLORIDE AND AN ALUMINUM ALKYL HALIDE | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-02-08 | — | — | US | disclosed |
| US-4007132-A | Process for the manufacture of a catalyst | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-02-08 | — | — | US | disclosed |