Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA known ✓ | P21397 | 2/20 | 0.57 |
| ▸ | S1PR4 known ✓ | O95977 | 1/20 | 0.57 |
| ▸ | BCHE known ✓ | P06276 | 1/20 | 0.57 |
| ▸ | S1PR1 known ✓ | P21453 | 1/20 | 0.57 |
| ▸ | PPARG known ✓ | P37231 | 1/20 | 0.57 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | S100A4 | P26447 | 2/20 | 0.57 |
| ▸ | APAF1 | O14727 | 2/20 | 0.57 |
| ▸ | TDP2 | O95551 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.57 |
| ▸ | TERT | O14746 | 1/20 | 0.57 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29020358 | 1.00 | MEN1 (0.57) | MEN1KMT2AMAPK1NPC1MAOA | |
| Hydrochloric Acid SCHEMBL31484610 | 1.00 | MEN1 (0.57) | MEN1KMT2AMAPK1NPC1MAOA | |
| Hydrochloric Acid SCHEMBL28596065 | 0.95 | MEN1 (0.53) | MEN1KMT2AMAPK1NPC1MAOA | |
| Hydrochloric Acid SCHEMBL2296340 | 0.95 | MEN1 (0.53) | MEN1KMT2AMAPK1NPC1MAOA | |
| SCHEMBL4368339 | 0.94 | MEN1 (0.61) | MEN1KMT2AMAPK1NPC1MAOA | |
| SCHEMBL28694051 | 0.94 | MEN1 (0.61) | MEN1KMT2AMAPK1NPC1MAOA | |
| SCHEMBL49870 | 0.94 | MEN1 (0.61) | MEN1KMT2AMAPK1NPC1MAOA | |
| SCHEMBL11875421 | 0.94 | MEN1 (0.61) | MEN1KMT2AMAPK1NPC1MAOA | |
| SCHEMBL58152 | 0.94 | MEN1 (0.61) | MEN1KMT2AMAPK1NPC1MAOA | |
| SCHEMBL29067593 | 0.94 | MEN1 (0.61) | MEN1KMT2AMAPK1NPC1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104017153-B | Polylactic acid resin composition | 三井化学株式会社 | 2017-01-11 | — | — | CN | disclosed |
| CN-104017152-B | The manufacture method of stereocomplex polylactic acid resin composition and stereocomplex polylactic acid resin composition | 三井化学株式会社 | 2016-06-29 | — | — | CN | disclosed |
| CN-104017153-A | Polylactic acid resin composition | MITSUI CHEMICALS INC | 2014-09-03 | — | — | CN | disclosed |
| CN-104017152-A | Stereocomplex polylactic acid resin composition and process for producing stereocomplex polylactic acid resin composition | MITSUI CHEMICALS INC | 2014-09-03 | — | — | CN | disclosed |
| CN-102459391-B | Polylactic acid resin, method for producing polylactic acid resin, polylactic acid resin composition, stereocomplex polylactic acid resin composition, and method for producing stereocomplex polylactic acid resin composition | MITSUI CHEMICALS INC | 2014-07-09 | — | — | CN | disclosed |
| CN-101522745-B | Photolatent bases for systems based on blocked isocyanates | CIBA HOLDING INC | 2013-06-19 | — | — | CN | disclosed |
| CN-102964556-A | Isocyanate-epoxy formulations for improved cure control | DOW GLOBAL TECHNOLOGIES INC | 2013-03-13 | — | — | CN | disclosed |
| CN-101945914-B | Polyester resin, a manufacturing method thereof and uses therefor | MITSUI CHEMICALS INC | 2012-12-26 | — | — | CN | disclosed |
| CN-102459391-A | Polylactic acid resin, method for producing polylactic acid resin, polylactic acid resin composition, stereocomplex polylactic acid resin composition, and method for producing stereocomplex polylactic acid resin composition | MITSUI CHEMICALS INC | 2012-05-16 | — | — | CN | disclosed |
| CN-102365344-A | Wellbore fluid and methods of treating an earthen formation | M I DRILLING FLUIDS UK LTD | 2012-02-29 | — | — | CN | disclosed |
| CN-101711262-A | Isocyanate-epoxy formulations for improved cure control | DOW GLOBAL TECHNOLOGIES INC | 2010-05-19 | — | — | CN | disclosed |
| CN-101522745-A | Photolatent bases for systems based on blocked isocyanates | CIBA SC HOLDING AG (CH) | 2009-09-02 | — | — | CN | disclosed |
| US-20090076019-A1 | METHODS FOR TREATING NEUROLOGICAL DISORDERS OR DAMAGE | MOUNT SINAI HOSPITAL (CA) | 2009-03-19 | — | — | US | disclosed |
| CN-1313554-C | Aqueous vacuum forming laminating adhesive composition, substrates and methods related thereto | PPG IND OHIO INC (US) | 2007-05-02 | — | — | CN | disclosed |
| CN-1268700-C | Thermosetting cathodic electrocoating compositions | VALSPAR SOURCING INC (US) | 2006-08-09 | — | — | CN | disclosed |
| CN-1685027-A | Aqueous vacuum forming laminating adhesive composition, substrates and methods related thereto | PPG IND OHIO INC (US) | 2005-10-19 | — | — | CN | disclosed |
| CN-1481426-A | Thermset cathodic electrocoat compsn | — | 2004-03-10 | — | — | CN | disclosed |
| US-4997580-A | Use of organic fluorochemical compounds with oleophobic and hydrophobic groups in crude oils as antideposition agents, and compositions thereof | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| US-4876018-A | Use of organic fluorochemical compounds with oleophobic and hydrophobic groups in asphaltenic crude oils as viscosity reducing agents | CIBA-GEIGY CORPORATION (US) | 1989-10-24 | — | — | US | disclosed |
| US-4769160-A | Use of organic fluorochemical compounds with oleophobic and hydrophobic groups in asphaltenic crude oils as viscosity reducing agents | CIBA-GEIGY CORPORATION (US) | 1988-09-06 | — | — | US | disclosed |