SCHEMBL433952

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8286028	0.78	AHR (0.42)	CYP1A2CYP2A6CYP1A1CYP1B1ALDH1A1
	SCHEMBL20125051	0.78	NQO1 (0.42)	CYP1A2CYP1A1CYP1B1ALDH1A1SMN1; SMN2
	SCHEMBL12778723	0.78	EYA3 (0.41)	CYP1A2CYP1A1CYP1B1ALDH1A1LMNA
	SCHEMBL5035815	0.78	CYP1A1 (0.40)	CYP1A2CYP1A1CYP1B1MAOAALDH1A1
	SCHEMBL12778694	0.78	CYP1A2 (0.43)	CYP1A2CYP1A1CYP1B1MAOAALDH1A1
	SCHEMBL2268151	0.78	MAOA (0.44)	CYP1A2CYP1A1CYP1B1MAOASMN1; SMN2
	SCHEMBL12728518	0.78	CYP1A1 (0.40)	CYP1A2CYP1A1CYP1B1SMN1; SMN2ACHE
	SCHEMBL23218380	0.78	CYP1A2 (0.42)	CYP1A2CYP2A6MAOAALDH1A1SMN1; SMN2
	SCHEMBL27921495	0.78	CYP1A2 (0.42)	CYP1A2CYP2A6MAOAALDH1A1SMN1; SMN2
	SCHEMBL4120120	0.78	CYP1A2 (0.53)	CYP1A2CYP1A1CYP1B1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.