Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12958120 | 0.84 | TSHR (0.43) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12958128 | 0.84 | TSHR (0.43) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL13002352 | 0.84 | TSHR (0.43) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8132195 | 0.82 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL433972 | 0.82 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12958129 | 0.80 | TSHR (0.39) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29087975 | 0.78 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10114980 | 0.78 | TSHR (0.48) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12002706 | 0.76 | TSHR (0.40) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL434075 | 0.75 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030902-B2 | Polymer crosslinking agent, and high molecular weight polymer and composition using same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2024-07-09 | — | — | US | disclosed |
| US-20170087080-A1 | LIPSTICK COMPOSITION IN EMULSION FORM COMPRISING A PARTICULAR FILM-FORMING POLYMER AND TREATMENT PROCESS EMPLOYING SAME | L'OREAL (FR) | 2017-03-30 | — | — | US | disclosed |
| US-20170027850-A1 | SOLID COMPOSITION WITH A VINYL POLYMER BEARING A CARBOSILOXANE DENDRIMER UNIT AND TWO INCOMPATIBLE PHENYL SILICONE OILS, AND TREATMENT PROCESS | L'OREAL (FR) | 2017-02-02 | — | — | US | disclosed |
| US-9260607-B2 | Surface-treatment agent for powder for use in cosmetic and cosmetic containing powder treated with the same | DOW CORNING TORAY CO., LTD. (JP) | 2016-02-16 | — | — | US | disclosed |
| US-20150305988-A1 | SOLID COSMETIC COMPOSITION IN PRESSED POWDER FORM | L"OREAL (FR) | 2015-10-29 | — | — | US | disclosed |
| US-8828372-B2 | Cosmetic composition comprising at least one vinyl polymer and at least one olefin copolymer | L'OREAL (FR) | 2014-09-09 | — | — | US | disclosed |
| US-20120251605-A1 | Surface-Treatment Agent For Powder For Use In Cosmetic And Cosmetic Containing Powder Treated With The Same | DOW TORAY CO., LTD. (JP) | 2012-10-04 | — | — | US | disclosed |
| US-20120064019-A1 | COSMETIC COMPOSITION FOR MAKING-UP AND/OR CARING FOR KERATIN MATERIALS AND MAKE-UP METHOD | L'OREAL (FR) | 2012-03-15 | — | — | US | disclosed |
| US-20100310489-A1 | COSMETIC MAKEUP AND/OR CARE PROCESS USING A SILOXANE RESIN AND A FILM-FORMING POLYMER | L'OREAL (FR) | 2010-12-09 | — | — | US | disclosed |
| US-7488492-B2 | Cosmetic raw material cosmetic product and method for manufacturing a cosmetic product | DOW CORNING TORAY COMPANY, LTD. (JP) | 2009-02-10 | — | — | US | disclosed |
| US-20080003195-A1 | Cosmetic composition comprising at least one vinyl polymer and at least one olefin copolymer | L'OREAL S.A. (FR) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150305988-A1 | SOLID COSMETIC COMPOSITION IN PRESSED POWDER FORM | CUTA, PLIN5, AUP1 | TSHR 2251/4885THRB 4365/4885POLB 677/4885 |
| US-20120064019-A1 | COSMETIC COMPOSITION FOR MAKING-UP AND/OR CARING FOR KERATIN MATERIALS AND MAKE-UP METHOD | PLOD3, ALOX15, ELOVL1 | TSHR 2894/4885THRB 747/4885POLB 563/4885 |
| US-20100310489-A1 | COSMETIC MAKEUP AND/OR CARE PROCESS USING A SILOXANE RESIN AND A FILM-FORMING POLYMER | SCO2, KRT18, CORO1C | TSHR 4099/4885THRB 1963/4885POLB 647/4885 |
| US-20170087080-A1 | LIPSTICK COMPOSITION IN EMULSION FORM COMPRISING A PARTICULAR FILM-FORMING POLYMER AND TREATMENT PROCESS EMPLOYING SAME | DGKZ, LMTK2, LPO | TSHR 4100/4885THRB 3322/4885POLB 488/4885 |
| US-12030902-B2 | Polymer crosslinking agent, and high molecular weight polymer and composition using same | SMCHD1, MUS81, MGLL | TSHR 4056/4885THRB 3963/4885POLB 1676/4885 |
| US-20080003195-A1 | Cosmetic composition comprising at least one vinyl polymer and at least one olefin copolymer | KRT18, DSG1, MARK1 | TSHR 4464/4885THRB 3072/4885POLB 797/4885 |
| US-20120251605-A1 | Surface-Treatment Agent For Powder For Use In Cosmetic And Cosmetic Containing Powder Treated With The Same | CUTA, GPKOW, TAS2R8 | TSHR 606/4885THRB 1203/4885POLB 1450/4885 |
| US-20170027850-A1 | SOLID COMPOSITION WITH A VINYL POLYMER BEARING A CARBOSILOXANE DENDRIMER UNIT AND TWO INCOMPATIBLE PHENYL SILICONE OILS, AND TREATMENT PROCESS | DCLRE1A, PIM1, VCL | TSHR 3776/4885THRB 2998/4885POLB 674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.