Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.46 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.38 |
| ▸ | P2RY2 known ✓ | P41231 | 1/20 | 0.35 |
| ▸ | P2RY4 known ✓ | P51582 | 1/20 | 0.35 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.34 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | PKLR | P30613 | 3/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | PGAM1 | P18669 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP12 | P39900 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | MMP14 | P50281 | 2/20 | 0.38 |
| ▸ | MMP16 | P51512 | 2/20 | 0.38 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30665407 | 1.00 | CYP2D6 (0.47) | CYP2D6CA12PKLRAPOBEC3GTHRB | |
| SCHEMBL10865908 | 0.84 | RAD51 (0.40) | CYP2D6CA12PKLRTHRBPTPN1 | |
| SCHEMBL28530830 | 0.83 | MMP2 (0.40) | CA12PKLRPTPN1PGAM1MMP2 | |
| SCHEMBL30125012 | 0.82 | DUSP5 (0.38) | CYP2D6CA12PKLRAPOBEC3GTHRB | |
| SCHEMBL28589728 | 0.82 | DUSP5 (0.38) | CYP2D6CA12PKLRAPOBEC3GTHRB | |
| SCHEMBL1058401 | 0.81 | CTSB (0.50) | CYP2D6CA12PKLRFTOP2RY2 | |
| SCHEMBL4434908 | 0.80 | CYP2D6 (0.56) | CYP2D6CA12APOBEC3GMMP2MMP8 | |
| SCHEMBL28459186 | 0.79 | PNMT (0.40) | CA12PKLRRAD51FTOP2RY2 | |
| SCHEMBL29538773 | 0.79 | FTO (0.39) | CYP2D6CA12PKLRPTPN1PGAM1 | |
| SCHEMBL10498135 | 0.79 | MMP2 (0.45) | MMP2MMP8MMP12MMP13MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111534265-B | Ionic polyurethane hot melt adhesive foam product and preparation method thereof | 美瑞新材料股份有限公司 | 2021-11-30 | — | — | CN | claimed |
| CN-111534265-A | Ionic polyurethane hot melt adhesive foam product and preparation method thereof | 美瑞新材料股份有限公司 | 2020-08-14 | — | — | CN | claimed |
| CN-116137818-A | Para-amino-benzyl linkers, methods of making and use thereof in conjugates | 法国施维雅药厂 | 2023-05-19 | — | — | CN | disclosed |
| CN-113816376-B | Special binder for coal-based activated carbon and preparation method thereof | 国家能源集团宁夏煤业有限责任公司 | 2023-05-09 | — | — | CN | disclosed |
| EP-1218385-B1 | CARBON MONOXIDE SOURCE FOR PREPARATION OF TRANSITION-METAL-CARBONYL-COMPLEXES | MALLINCKRODT INC (US) | 2009-01-07 | — | — | EP | disclosed |
| US-7188725-B2 | Kits for preparing transition metal carbonyl complexes | MALLINCKRODT INC. (US) | 2007-03-13 | — | — | US | disclosed |
| US-7053242-B1 | Carbon monoxide source for preparation of transition-metal-carbonyl-complexes | MALLINCKRODT INC. (US) | 2006-05-30 | — | — | US | disclosed |
| US-20060030722-A1 | Kits for preparing transition metal carbonyl complexes | MALLINCKRODT ENTERPRISES HOLDINGS LLC (F/K/A MALLINCKRODT ENTERPRISES HOLDINGS, INC.) | 2006-02-09 | — | — | US | disclosed |
| EP-1218385-A1 | CARBON MONOXIDE SOURCE FOR PREPARATION OF TRANSITION-METAL-CARBONYL-COMPLEXES | Mallinckrodt Inc. (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001025243-A1 | CARBON MONOXIDE SOURCE FOR PREPARATION OF TRANSITION-METAL-CARBONYL-COMPLEXES | MALLINCKRODT INC. (US) | 2001-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060030722-A1 | Kits for preparing transition metal carbonyl complexes | SOD1, CYC1, MT-CO2 | CA12 251/4885THRB 4379/4885P2RY2 4806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.