Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Prochloraz. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 5/20 | 0.40 |
| ▸ | ADRB1 known ✓ | P08588 | 5/20 | 0.40 |
| ▸ | ADRB3 known ✓ | P13945 | 5/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.96 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Prochloraz SCHEMBL11375792 | 0.99 | AHR (0.98) | AHRADRB2ADRB1ADRB3MEN1 | |
| Prochloraz SCHEMBL1092013 | 0.99 | AHR (0.98) | AHRADRB2ADRB1ADRB3MEN1 | |
| Prochloraz SCHEMBL10346525 | 0.99 | AHR (0.98) | AHRADRB2ADRB1ADRB3MEN1 | |
| Prochloraz SCHEMBL5581904 | 0.99 | AHR (0.98) | AHRADRB2ADRB1ADRB3MEN1 | |
| Prochloraz SCHEMBL14166134 | 0.98 | AHR (0.96) | AHRADRB2ADRB1ADRB3MEN1 | |
| Prochloraz SCHEMBL34675 | 0.98 | AHR (1.00) | AHRADRB2ADRB1ADRB3MEN1 | |
| Prochloraz SCHEMBL22242 | 0.98 | AHR (1.00) | AHRADRB2ADRB1ADRB3MEN1 | |
| Prochloraz SCHEMBL12611119 | 0.97 | AHR (0.98) | AHRADRB2ADRB1ADRB3MEN1 | |
| Prochloraz SCHEMBL9371936 | 0.97 | AHR (0.98) | AHRADRB2ADRB1ADRB3MEN1 | |
| Prochloraz SCHEMBL11376171 | 0.97 | AHR (0.98) | AHRADRB2ADRB1ADRB3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118240679-A | Biocontrol bacterium capable of controlling coffee diseases in cooperation with bactericide and application thereof | 中国热带农业科学院环境与植物保护研究所 | 2024-06-25 | — | — | CN | claimed |
| CN-117598312-A | Sterilization composition containing cyclopurifiuram and application thereof | 青岛海利尔生物科技有限公司 | 2024-02-27 | — | — | CN | claimed |
| CN-117481120-A | Bactericide composition for preventing and treating crop diseases caused by fusarium | 浙江省化工研究院有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-117322427-A | Use of benzovindiflupyr-containing bactericidal composition for preventing and controlling citrus anthracnose | 青岛奥迪斯生物科技有限公司 | 2024-01-02 | — | — | CN | claimed |
| CN-117016557-A | Bactericide composition for preventing and treating agaricus bisporus diseases and application thereof | 泰安市农业科学院 | 2023-11-10 | — | — | CN | claimed |
| CN-116868849-A | Rape cultivation method using straw and chicken manure compost as base fertilizer and application thereof | 华中农业大学 | 2023-10-13 | — | — | CN | claimed |
| CN-116530380-B | Dry land color rice landscape planting method | 云南省农业科学院粮食作物研究所 | 2023-09-26 | — | — | CN | claimed |
| CN-116530380-A | Dry land color rice landscape planting method | 云南省农业科学院粮食作物研究所 | 2023-08-04 | — | — | CN | claimed |
| CN-114208585-A | Method for cultivating pleurotus tuber-regium by imitating wild condition under forest | 贵州省农作物品种资源研究所 | 2022-03-22 | — | — | CN | claimed |
| CN-111466401-B | Bactericidal composition and application thereof | 广西壮族自治区农业科学院植物保护研究所 | 2021-08-03 | — | — | CN | claimed |
| US-20140194288-A1 | PLANT SUPPORT FORMULATION, VEHICLE FOR THE DELIVERY AND TRANSLOCATION OF PHYTOLOGICALLY BENEFICIAL SUBSTANCES AND COMPOSITIONS CONTAINING SAME | NORTH-WEST UNIVERSITY (ZA) | 2014-07-10 | — | — | US | claimed |
| US-20120302442-A1 | PLANT SUPPORT FORMULATION, VEHICLE FOR THE DELIVERY AND TRANSLOCATION OF PHYTOLOGICALLY BENEFICIAL SUBSTANCES AND COMPOSITIONS CONTAINING SAME | NORTH-WEST UNIVERSITY (ZA) | 2012-11-29 | — | — | US | claimed |
| CN-101564042-A | Dimethomorph and prochloraz compounded bactericidal composition | JIANGSU HUIFENG AGROCHEMICAL C (CN) | 2009-10-28 | — | — | CN | claimed |
| US-20090192040-A1 | PLANT SUPPORT FORMULATION, VEHICLE FOR THE DELIVERY AND TRANSLOCATION OF PHYTOLOGICALLY BENEFICAL SUBSTANCES AND COMPOSITIONS CONTAINING SAME | NORTH-WEST UNIVERSITY (ZA) | 2009-07-30 | — | — | US | claimed |
| EP-1988774-A2 | COMPOSITION IN THE FORM OF A MICROEMULSION CONTAINING FREE FATTY ACIDS AND/OR FREE FATTY ACID DERIVATIVES | North-West University (ZA) | 2008-11-12 | — | — | EP | claimed |
| WO-2007096833-A2 | COMPOSITION IN THE FORM OF A MICROEMULSION CONTAINING FREE FATTY ACIDS AND/OR FREE FATTY ACID DERIVATIVES | NORTH-WEST UNIVERSITY (ZA) | 2007-08-30 | — | — | WO | claimed |
| CN-118240679-A | Biocontrol bacterium capable of controlling coffee diseases in cooperation with bactericide and application thereof | 中国热带农业科学院环境与植物保护研究所 | 2024-06-25 | — | — | CN | disclosed |
| CN-117598312-A | Sterilization composition containing cyclopurifiuram and application thereof | 青岛海利尔生物科技有限公司 | 2024-02-27 | — | — | CN | disclosed |
| WO-2007096833-A2 | COMPOSITION IN THE FORM OF A MICROEMULSION CONTAINING FREE FATTY ACIDS AND/OR FREE FATTY ACID DERIVATIVES | NORTH-WEST UNIVERSITY (ZA) | 2007-08-30 | — | — | WO | disclosed |
| WO-2007066208-A1 | PESTICIDAL COMBINATIONS | BITRAD TRUST (ZA) | 2007-06-14 | — | — | WO | disclosed |