SCHEMBL454724

SCHEMBL454724

C=C(CCCCCCCCCCC)C(=O)NCS(=O)(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.42
PLA2G2A P14555 3/20 0.41
CASP2 P42575 1/20 0.41
EPHX1 P07099 4/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
HSP90AA1 P07900 1/20 0.39
ZDHHC20 Q5W0Z9 1/20 0.39
ZDHHC2 Q9UIJ5 1/20 0.39
NAAA Q02083 1/20 0.39
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
SLC22A6 Q4U2R8 1/20 0.38
SLC22A8 Q8TCC7 1/20 0.38
GPR84 Q9NQS5 1/20 0.38
PPARG P37231 1/20 0.38
PPARD Q03181 1/20 0.38
PPARA Q07869 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11766242 0.84 PLA2G2A (0.46) FAAHPLA2G2ACASP2EPHX1CA1
SCHEMBL7161002 0.82 PLA2G2A (0.59) FAAHPLA2G2ACASP2EPHX1ZDHHC20
SCHEMBL720662 0.80 FAAH (0.59) FAAHPLA2G2ACES2CES1HSP90AA1
SCHEMBL12256836 0.76 PLA2G2A (0.69) FAAHPLA2G2AALDH1A1TSHRSLC22A6
SCHEMBL28719973 0.75 THRB (0.48) CES2CES1ALDH1A1TSHRSLC22A6
SCHEMBL14138655 0.75 CASP2 (0.60) FAAHPLA2G2ACASP2EPHX1ZDHHC20
SCHEMBL6280150 0.75 NAAA (0.56) PLA2G2ACASP2EPHX1ZDHHC20ZDHHC2
SCHEMBL8085527 0.74 HSP90AA1 (0.57) FAAHCES2CES1HSP90AA1ALDH1A1
SCHEMBL4754540 0.74 CES2 (0.48) FAAHCES2CES1HSP90AA1ALDH1A1
SCHEMBL28787438 0.74 CES2 (0.43) FAAHCES2CES1HSP90AA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 293 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3386476-A1 COMPOSITION COMPRISING A POLYMER CONTAINING A SULFONIC MONOMER AND A PYRIDINEDICARBOXYLIC ACID DERIVATIVE, AND COSMETIC TREATMENT METHOD L'Oréal (FR) 2018-10-17 EP claimed
WO-2017097849-A1 COMPOSITION COMPRISING A POLYMER CONTAINING A SULFONIC MONOMER AND A PYRIDINEDICARBOXYLIC ACID DERIVATIVE, AND COSMETIC TREATMENT METHOD L'OREAL (FR) 2017-06-15 WO claimed
US-7217298-B2 Ready-to-use bleaching compositions, preparation process and bleaching process L'OREAL S.A. (FR) 2007-05-15 US claimed
EP-1325729-B1 Composition containing a silicone copolymer and either a polymer from an ethylenically unsaturated monomer with sulfonic groups or an organic powder; uses thereof, especially in cosmetics OREAL (FR) 2006-04-19 EP claimed
US-20040235700-A1 Ready-to-use bleaching compositions, preparation process and bleaching process L'OREAL S.A. (FR) 2004-11-25 US claimed
EP-4547208-B1 PROCESS FOR REMOVING THE COLOUR FROM PREVIOUSLY DYED KERATINOUS HAIR FIBRES OREAL (FR) 2026-05-27 EP disclosed
CN-122094656-A Method for dyeing hair keratin fibres, comprising the step of washing the hair keratin fibres with a particular composition and subsequently applying to the hair keratin fibres a particular dyeing composition 2026-05-26 CN disclosed
US-12636246-B2 Process for colouring hair keratin fibers, comprising the application of a composition comprising at least one (poly)carbodiimide compound and a composition comprising at least one associative polymer and a particular compound L'OREAL (FR) 2026-05-26 US disclosed
EP-4734951-A1 COMPOSITION FOR CONDITIONING THE HAIR L'OREAL (FR) 2026-05-06 EP disclosed
EP-3389618-B2 PROCESS FOR TREATING KERATIN FIBRES USING AN AQUEOUS COMPOSITION COMPRISING A COMBINATION OF PARTICULAR ALKOXYSILANES OREAL (FR) 2026-04-22 EP disclosed
US-12576015-B2 Antimicrobial mixture containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one and an alcohol compound, and cosmetic composition containing same L'OREAL (FR) 2026-03-17 US disclosed
US-12576016-B2 Composition containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one, a preservative and/or antioxidant, a surfactant and a polymer, and the method for processing keratin materials from the composition L'OREAL (FR) 2026-03-17 US disclosed
US-20040074015-A1 Oxidising composition for treating keratinous materials based on amphiphilic polymers of at least an ethylenically unsaturated monomer containing a sulfonic group and comprising a hydrophobic part L'OREAL (FR) 2004-04-22 US disclosed
US-20040071641-A1 Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers SOCIETE L'OREAL S.A. (FR) 2004-04-15 US disclosed
US-20040062728-A1 Photoprotective compositions comprising sulfonic/hydrophobic amphiphilic polymers SOCIETE L'OREAL, S.A. (FR) 2004-04-01 US disclosed
US-20030171479-A1 Composition containing a silicone copolymer and an amps-like polymer and/or organic powder L'OREAL (FR) 2003-09-11 US disclosed
US-20030157047-A1 Cosmetic composition for removing make-up from and clening the skin L'OREAL (FR) 2003-08-21 US disclosed
US-20030108577-A1 Cosmetic and/or dermatological acid composition containing an amphiphilic polymer L'OREAL (FR) 2003-06-12 US disclosed
US-20030050201-A1 Cleansing composition containing an amphiphilic polymer L'OREAL (FR) 2003-03-13 US disclosed
US-20030036490-A1 Stable composition with high electrolyte content containing an amphiphilic polymer L'OREAL (FR) 2003-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030157047-A1 Cosmetic composition for removing make-up from and clening the skin CUTA, DEGS1, LAGE3 FAAH 118/4885PLA2G2A 866/4885CASP2 3517/4885
US-20040062728-A1 Photoprotective compositions comprising sulfonic/hydrophobic amphiphilic polymers CUTA, PCNA, DSG1 FAAH 202/4885PLA2G2A 1605/4885CASP2 2571/4885
US-12576015-B2 Antimicrobial mixture containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one and an alcohol compound, and cosmetic composition containing same EBP, CUTA, HAO2 FAAH 3018/4885PLA2G2A 3732/4885CASP2 124/4885
US-20040071641-A1 Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers CUTA, DSG1, PCNA FAAH 475/4885PLA2G2A 1272/4885CASP2 2503/4885
US-20030108577-A1 Cosmetic and/or dermatological acid composition containing an amphiphilic polymer KRT18, DSG1, CUTA FAAH 55/4885PLA2G2A 179/4885CASP2 3521/4885
US-12576016-B2 Composition containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one, a preservative and/or antioxidant, a surfactant and a polymer, and the method for processing keratin materials from the composition KRT18, BAK1, GPX4 FAAH 3501/4885PLA2G2A 2741/4885CASP2 38/4885
US-12636246-B2 Process for colouring hair keratin fibers, comprising the application of a composition comprising at least one (poly)carbodiimide compound and a composition comprising at least one associative polymer and a particular compound KRT18, CYC1, CYBA FAAH 2785/4885PLA2G2A 3957/4885CASP2 3157/4885
US-20030171479-A1 Composition containing a silicone copolymer and an amps-like polymer and/or organic powder SPPL2B, CALCB, CALCA FAAH 4040/4885PLA2G2A 1445/4885CASP2 1170/4885
US-20030036490-A1 Stable composition with high electrolyte content containing an amphiphilic polymer KRT18, DSG1, SCNN1A FAAH 586/4885PLA2G2A 853/4885CASP2 3650/4885
US-20040074015-A1 Oxidising composition for treating keratinous materials based on amphiphilic polymers of at least an ethylenically unsaturated monomer containing a sulfonic group and comprising a hydrophobic part KRT18, DSG1, CUTA FAAH 502/4885PLA2G2A 675/4885CASP2 3038/4885
US-20030050201-A1 Cleansing composition containing an amphiphilic polymer UGCG, SGMS1, SGMS2 FAAH 273/4885PLA2G2A 417/4885CASP2 3533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.