Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251120 | 0.95 | — | — | |
| Bromide SCHEMBL941951 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL7530764 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL27275310 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL29425309 | 0.63 | — | — | |
| SCHEMBL546972 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL7986636 | 0.60 | — | — | |
| Hydrochloric Acid SCHEMBL9419899 | 0.60 | — | — | |
| Hydrochloric Acid SCHEMBL1486869 | 0.60 | — | — | |
| Allyl Alcohol SCHEMBL4601219 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630781-B1 | PREPARATION OF TRAIL KYLINDIUM COMPOUNDS IN THE PRESENCE OF CARBOXYLATES | UMICORE AG & CO KG (DE) | 2021-05-05 | — | — | EP | claimed |
| EP-3409676-B1 | PREPARATION OF TRAIL KYLINDIUM COMPOUNDS IN THE PRESENCE OF CARBOXYLATES | UMICORE AG & CO KG (DE) | 2020-10-14 | — | — | EP | claimed |
| CN-105473598-A | Method for producing alkyl indium compound and use thereof | UMICORE AG & CO KG | 2016-04-06 | — | — | CN | claimed |
| EP-3256478-B1 | PROCESS FOR PREPARING ALKYL-INDIUM COMPOUNDS AND THE USE THEREOF | UMICORE AG & CO KG (DE) | 2020-10-28 | — | — | EP | disclosed |
| US-10745421-B2 | Method for producing alkyl-indium compounds and the use thereof | UMICORE AG & CO. KG (DE) | 2020-08-18 | — | — | US | disclosed |
| US-10385073-B2 | Process for preparing alkyl-indium compounds and the use thereof | UMIICORE AG & CO. KG (DE) | 2019-08-20 | — | — | US | disclosed |
| US-10385073-B2 | Process for preparing alkyl-indium compounds and the use thereof | UMIICORE AG & CO. KG (DE) | 2019-08-20 | — | — | US | disclosed |
| US-20190194229-A1 | METHOD FOR PRODUCING ALKYL-INDIUM COMPOUNDS AND THE USE THEREOF | UMICORE AG & CO. KG (DE) | 2019-06-27 | — | — | US | disclosed |
| US-10239892-B2 | Method for producing alkyl-indium compounds and the use thereof | UMICORE AG & CO. KG (DE) | 2019-03-26 | — | — | US | disclosed |
| CN-105473598-B | Method for producing alkyl indium compound and use thereof | 优美科股份公司及两合公司 | 2018-05-08 | — | — | CN | disclosed |
| EP-3256478-A1 | PROCESS FOR PREPARING ALKYL-INDIUM COMPOUNDS AND THE USE THEREOF | Umicore AG & Co. KG (DE) | 2017-12-20 | — | — | EP | disclosed |
| US-20160207942-A1 | METHOD FOR PRODUCING ALKYL-INDIUM COMPOUNDS AND THE USE THEREOF | UMICORE AG & CO. KG (DE) | 2016-07-21 | — | — | US | disclosed |
| EP-3036243-A1 | METHOD FOR PRODUCING ALKYL-INDIUM COMPOUNDS AND THE USE THEREOF | Umicore AG & Co. KG (DE) | 2016-06-29 | — | — | EP | disclosed |
| CN-105473598-A | Method for producing alkyl indium compound and use thereof | UMICORE AG & CO KG | 2016-04-06 | — | — | CN | disclosed |
| CN-105473598-A | Method for producing alkyl indium compound and use thereof | UMICORE AG & CO KG | 2016-04-06 | — | — | CN | disclosed |
| WO-2015024894-A1 | METHOD FOR PRODUCING ALKYL-INDIUM COMPOUNDS AND THE USE THEREOF | UMICORE AG & CO. KG (DE) | 2015-02-26 | — | — | WO | disclosed |
| EP-1643547-B1 | Preparation of group 12 and 13 metal compounds having low levels of oxygenated impurities | ROHM & HAAS ELECT MAT (US) | 2008-11-05 | — | — | EP | disclosed |
| US-7166734-B2 | Method for making organometallic compounds | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2007-01-23 | — | — | US | disclosed |
| EP-1643547-A1 | Preparation of group 12 and 13 metal compounds having low levels of oxygenated impurities | Rohm and Haas Electronic Materials, L.L.C. (US) | 2006-04-05 | — | — | EP | disclosed |
| US-20060047132-A1 | Method | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2006-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10385073-B2 | Process for preparing alkyl-indium compounds and the use thereof | ENY2, RPS4Y1, RPS4X | TSHR 4525/4885ALDH1A1 3475/4885TRPA1 2147/4885 |
| US-20190194229-A1 | METHOD FOR PRODUCING ALKYL-INDIUM COMPOUNDS AND THE USE THEREOF | RPS4Y1, ENY2, RPS4X | TSHR 4481/4885ALDH1A1 2914/4885TRPA1 2234/4885 |
| US-10239892-B2 | Method for producing alkyl-indium compounds and the use thereof | RPS4Y1, ENY2, RPS4X | TSHR 4375/4885ALDH1A1 2831/4885TRPA1 2013/4885 |
| US-20160207942-A1 | METHOD FOR PRODUCING ALKYL-INDIUM COMPOUNDS AND THE USE THEREOF | RPS4Y1, ENY2, RPS4X | TSHR 4481/4885ALDH1A1 2914/4885TRPA1 2234/4885 |
| US-10745421-B2 | Method for producing alkyl-indium compounds and the use thereof | RPS4Y1, ENY2, RPS4X | TSHR 4481/4885ALDH1A1 2914/4885TRPA1 2234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.