Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10636896 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL1232708 | 0.96 | — | — | |
| Ammonia Solution, Strong SCHEMBL797498 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL7717763 | 0.96 | TSHR (0.36) | TSHRALDH1A1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL220991 | 0.96 | — | — | |
| Bromide SCHEMBL29011445 | 0.92 | TSHR (0.35) | TSHRALDH1A1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL29043280 | 0.92 | TSHR (0.35) | TSHRALDH1A1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL2334306 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL28077119 | 0.92 | TSHR (0.35) | TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL27922143 | 0.92 | TSHR (0.38) | TSHRALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107949674-B | Multilayer cardboard material and method for producing a multilayer cardboard material | 迈尔-梅林霍夫纸板箱股份公司 | 2020-12-08 | — | — | CN | disclosed |
| US-8679850-B2 | Methods of cationic polymer detection | GENERAL ELECTRIC COMPANY (US) | 2014-03-25 | — | — | US | disclosed |
| US-20120270328-A1 | Methods of Cationic Polymer Detection | GENERAL ELECTRIC COMPANY (CN) | 2012-10-25 | — | — | US | disclosed |
| WO-2012083492-A1 | METHODS OF CATIONIC POLYMER DETECTION | GENERAL ELECTRIC COMPANY (US) | 2012-06-28 | — | — | WO | disclosed |
| US-7465322-B2 | Nacreous colorant for keratin fibers | WELLA AG (DE) | 2008-12-16 | — | — | US | disclosed |
| US-20070151043-A1 | Nacreous colorant for keratin fibers | Wella GmbH (DE) | 2007-07-05 | — | — | US | disclosed |
| EP-1159459-B1 | A DETECTABLE CATIONIC FLOCCULANT AND METHOD OF USING SAME IN INDUSTRIAL FOOD PROCESSES | NALCO CHEMICAL CO (US) | 2006-05-31 | — | — | EP | disclosed |
| EP-1159459-A4 | A DETECTABLE CATIONIC FLOCCULANT AND METHOD OF USING SAME IN INDUSTRIAL FOOD PROCESSES | NALCO CHEMICAL CO (US) | 2003-03-05 | — | — | EP | disclosed |
| EP-1021573-B1 | MINERAL PELLETISATION | CIBA SPEC CHEM WATER TREAT LTD (GB) | 2002-03-06 | — | — | EP | disclosed |
| EP-1159459-A1 | A DETECTABLE CATIONIC FLOCCULANT AND METHOD OF USING SAME IN INDUSTRIAL FOOD PROCESSES | NALCO CHEMICAL COMPANY (US) | 2001-12-05 | — | — | EP | disclosed |
| US-6293994-B1 | MIXING PARTICULATE MINERAL MATERIAL WITH MOISTURE AND BINDER COMPRISING WATER SOLUBLE ORGANIC POLYMER AND ALKALI METAL SILICATE TO FORM A MOIST PELLETISABLE MIX, PELLETISING MOIST MIX BY TUMBLING TO FORM GREEN PELLETS AND FIRING PELLETS | CIBA SPECIALTY CHEMICALS WATER TREATMENTS LTD. (GB) | 2001-09-25 | — | — | US | disclosed |
| US-6238486-B1 | COMPRISING ADDITION TERPOLYMER OF A NONIONIC MONOMER-CATIONIC MONOMER-DIALLYLDIMETHYLAMMONIUM CHLORIDE WHOSE CONCENTRATION MAY BE DETERMINED BY SELECTIVE BINDING BY MONOCLONAL ANTIBODIES; SUGAR PROCESSING | NALCO CHEMICAL COMPANY | 2001-05-29 | — | — | US | disclosed |
| WO-2000053815-A1 | A DETECTABLE CATIONIC FLOCCULANT AND METHOD OF USING SAME IN INDUSTRIAL FOOD PROCESSES | NALCO CHEMICAL COMPANY (US) | 2000-09-14 | — | — | WO | disclosed |
| EP-1021573-A1 | MINERAL PELLETISATION | Ciba Specialty Chemicals Water Treatments Limited (GB) | 2000-07-26 | — | — | EP | disclosed |
| WO-1999018247-A1 | MINERAL PELLETISATION | CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) | 1999-04-15 | — | — | WO | disclosed |
| US-RE32459-E | CINNAMIC ACID THINNER | AKZO N.V. (NL) | 1987-07-14 | — | — | US | disclosed |
| EP-0130962-A1 | Viscosity modifiers for acrylamide polymer | MONSANTO COMPANY (US) | 1985-01-09 | — | — | EP | disclosed |
| US-4433090-A | CINNAMIC ACID | MONSANTO COMPANY (US) | 1984-02-21 | — | — | US | disclosed |