Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Methenamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methenamine SCHEMBL1626497 | 0.94 | KDM4E (0.31) | — | |
| Methenamine SCHEMBL541058 | 0.88 | — | — | |
| Methenamine SCHEMBL2988857 | 0.88 | — | — | |
| Methenamine SCHEMBL388812 | 0.88 | — | — | |
| Methenamine SCHEMBL8901393 | 0.88 | — | — | |
| Methenamine SCHEMBL11529258 | 0.88 | — | — | |
| Methenamine SCHEMBL3412566 | 0.88 | — | — | |
| Methenamine SCHEMBL6697487 | 0.88 | — | — | |
| Methenamine SCHEMBL1261085 | 0.88 | — | — | |
| Methenamine SCHEMBL7459586 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113457720-A | HMS @ NiPt @ Beta core-shell structure catalytic material and preparation method and application thereof | 东南大学 | 2021-10-01 | — | — | CN | claimed |
| CN-112742445-A | Selective hydrogenation molecular sieve material and preparation method thereof | 中国石油化工股份有限公司 | 2021-05-04 | — | — | CN | claimed |
| CN-118320833-A | Hydrogenation catalyst composition and preparation method and application thereof | 中科(广东)炼化有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-115572880-B | High-entropy metallocenes, preparation method and application thereof | 华南理工大学 | 2023-06-16 | — | — | CN | disclosed |
| CN-113457720-A | HMS @ NiPt @ Beta core-shell structure catalytic material and preparation method and application thereof | 东南大学 | 2021-10-01 | — | — | CN | disclosed |
| US-20120309952-A1 | SMALL RNA PURIFICATION | PROMEGA CORPORATION (US) | 2012-12-06 | — | — | US | disclosed |
| EP-1996730-A2 | SMALL RNA PURIFICATION | PROMEGA CORPORATION (US) | 2008-12-03 | — | — | EP | disclosed |
| US-20070269991-A1 | SEMICONDUCTOR NANOCRYSTAL-METAL COMPLEX AND METHOD OF PREPARING THE SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2007-11-22 | — | — | US | disclosed |
| EP-1857575-A2 | Semiconductor nanocrystal-metal complex and method of preparing the same | Samsung Electronics Co., Ltd. (KR) | 2007-11-21 | — | — | EP | disclosed |
| US-20070249821-A1 | Small RNA purification | PROMEGA CORPORATION (US) | 2007-10-25 | — | — | US | disclosed |
| WO-2007103485-A2 | SMALL RNA PURIFICATION | PROMEGA CORPORATION (US) | 2007-09-13 | — | — | WO | disclosed |
| US-20040102654-A1 | Process facilitating the regeneration of a catalyst based on a zeolite used in an acylation reaction, catalyst and use | SPAGNOL MICHEL (FR) | 2004-05-27 | — | — | US | disclosed |
| US-20020120169-A1 | Process facilitating the regeneration of a catalyst based on a zeolite used in an acylation reaction, catalyst and use | SPAGNOL MICHEL (FR) | 2002-08-29 | — | — | US | disclosed |
| CN-1107440-A | Process for preparing metal hydroxides | STARCK H C GMBH CO KG (DE) | 1995-08-30 | — | — | CN | disclosed |
| US-4628130-A | Process for producing alcohols by hydrogenolysis of carboxylic acid esters in the presence of a catalyst containing nickel and tin, germanium or lead | INSTITUT FRANCAIS DU PETROLE (FR) | 1986-12-09 | — | — | US | disclosed |
| US-4069164-A | COBALT-CONTAINING IRON OXIDE, OXIDIZER | FUJI PHOTO FILM CO., LTD. (JA) | 1978-01-17 | — | — | US | disclosed |