SCHEMBL5207843

SCHEMBL5207843

CC(C)C1NC(=O)CC1=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.32
CTSD P07339 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5924240 1.00 ABCB1 (0.32) ABCB1CTSD
SCHEMBL5207835 1.00 ABCB1 (0.32) ABCB1CTSD
SCHEMBL5924497 0.82
SCHEMBL5924319 0.79 KDM4E (0.41) CTSD
SCHEMBL16080204 0.77 ABCB1 (0.30) ABCB1
SCHEMBL25484894 0.77 CTSD (0.32) ABCB1CTSD
SCHEMBL24443112 0.77
SCHEMBL24743669 0.74 PLA2G10 (0.31)
SCHEMBL15359750 0.69 SMN1; SMN2 (0.33)
SCHEMBL10326860 0.69 AHR (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026088071-A1 SUBSTITUTED FUSED HETEROARYL LACTAM COMPOUNDS PFIZER INC. (US) 2026-04-30 WO disclosed
US-20260069602-A1 COMPOUNDS, COMPOSITIONS, AND METHODS ACONCAGUA BIO INC (US) 2026-03-12 US disclosed
US-12037324-B2 Biarylmethyl heterocycles BRISTOL-MYERS SQUIBB COMPANY (US) 2024-07-16 US disclosed
US-20230373937-A1 INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. 2023-11-23 US disclosed
US-20230357253-A1 AGONISTS OF STIMULATOR OF INTERFERON GENES STING THE SCRIPPS RESEARCH INSTITUTE 2023-11-09 US disclosed
US-20230346781-A1 SMALL MOLECULE INHIBITORS OF CANCER STEM CELLS AND MESENCHYMAL CANCER TYPES THE SCRIPPS RESEARCH INSTITUTE (US) 2023-11-02 US disclosed
US-20230310424-A1 METHODS AND MATERIALS FOR INCREASING NICOTINAMIDE PHOSPHORIBOSYL TRANSFERASE ACTIVITY UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2023-10-05 US disclosed
US-20230265055-A1 STAT INIHIBITORY COMPOUNDS AND COMPOSITIONS OXFORD FINANCE LLC 2023-08-24 US disclosed
US-11712485-B2 Triazine based radiopharmaceuticals and radioimaging agents MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2023-08-01 US disclosed
WO-2023118576-A1 DHODH INHIBITORS CONTAINING A CARBOXYLIC ACID BIOISOSTERE IMMUNIC AG (DE) 2023-06-29 WO disclosed
US-20070207949-A1 Medicaments and methods combining a HCV protease inhibitor and an AKR competitor SCHERING CORPORATION 2007-09-06 US disclosed
US-20070088163-A1 Modulators of calcitonin and amylin activity KEMIA, INC. 2007-04-19 US disclosed
US-20070088163-A1 Modulators of calcitonin and amylin activity KEMIA, INC. 2007-04-19 US disclosed
US-20070088163-A1 Modulators of calcitonin and amylin activity KEMIA, INC. 2007-04-19 US disclosed
US-20070021351-A1 Liver/plasma concentration ratio for dosing hepatitis C virus protease inhibitor SCHERING CORPORATION 2007-01-25 US disclosed
US-20070010431-A1 Pharmaceutical formulations and methods of treatment using the same SCHERING CORPORATION 2007-01-11 US disclosed
US-20070004635-A1 Method of treating interferon non-responders using HCV protease inhibitor SCHERING CORPORATION 2007-01-04 US disclosed
US-20060089316-A1 Method for reducing a susceptibility to tumor formation induced by 3-deoxyglucosone and precursors thereof BROWN TRUMAN R 2006-04-27 US disclosed
WO-2005025504-A2 MODULATORS OF CALCITONIN AND AMYLIN ACTIVITY KEMIA, INC. (US) 2005-03-24 WO disclosed
US-5534540-A CROSSLINKING AND DISCOLORATION INHIBITION; PRESERVING FOODS; AGING RESISTANCE ALTEON INC. (US) 1996-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230310424-A1 METHODS AND MATERIALS FOR INCREASING NICOTINAMIDE PHOSPHORIBOSYL TRANSFERASE ACTIVITY NAMPT, NNMT, NAPRT ABCB1 3132/4885CTSD 948/4885
US-20060089316-A1 Method for reducing a susceptibility to tumor formation induced by 3-deoxyglucosone and precursors thereof ALDOA, FBP1, GYS2 ABCB1 4361/4885CTSD 3411/4885
US-20070004635-A1 Method of treating interferon non-responders using HCV protease inhibitor IFNAR1, IFNG, IRF3 ABCB1 2521/4885CTSD 348/4885
US-20070088163-A1 Modulators of calcitonin and amylin activity CALCRL, CALCR, CALCA ABCB1 3860/4885CTSD 110/4885
US-11712485-B2 Triazine based radiopharmaceuticals and radioimaging agents PSMA2, PSMA5, PSMA1 ABCB1 1492/4885CTSD 955/4885
US-20230346781-A1 SMALL MOLECULE INHIBITORS OF CANCER STEM CELLS AND MESENCHYMAL CANCER TYPES VIM, CDH1, BRCA1 ABCB1 1036/4885CTSD 1597/4885
US-20070021351-A1 Liver/plasma concentration ratio for dosing hepatitis C virus protease inhibitor PYGL, SERPINB1, PREP ABCB1 640/4885CTSD 427/4885
US-20070010431-A1 Pharmaceutical formulations and methods of treatment using the same LPXN, SLC5A11, F12 ABCB1 115/4885CTSD 3813/4885
US-20230357253-A1 AGONISTS OF STIMULATOR OF INTERFERON GENES STING STING1, IRF3, CGAS ABCB1 2730/4885CTSD 2813/4885
US-12037324-B2 Biarylmethyl heterocycles ARRB1, ADRB2, ADRB1 ABCB1 601/4885CTSD 3143/4885
US-20230373937-A1 INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY SPNS2, SPCS2, SMN1; SMN2 ABCB1 1186/4885CTSD 4096/4885
US-20070207949-A1 Medicaments and methods combining a HCV protease inhibitor and an AKR competitor CTSV, AKR1B1, AKR1A1 ABCB1 852/4885CTSD 26/4885
US-20230265055-A1 STAT INIHIBITORY COMPOUNDS AND COMPOSITIONS STAT5B, STAT5A, STAT3 ABCB1 3446/4885CTSD 4213/4885
US-20260069602-A1 COMPOUNDS, COMPOSITIONS, AND METHODS SCTR, SSTR1, NPY1R ABCB1 2853/4885CTSD 1596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.