Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Isophthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.68 |
| ▸ | CA12 | O43570 | 1/20 | 0.68 |
| ▸ | CA1 | P00915 | 1/20 | 0.68 |
| ▸ | CA6 | P23280 | 1/20 | 0.68 |
| ▸ | CA9 | Q16790 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | DAO | P14920 | 1/20 | 0.63 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.63 |
| ▸ | KMO | O15229 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | UNG | P13051 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isophthalic Acid SCHEMBL377398 | 1.00 | CA12 (0.68) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL9241794 | 1.00 | CA12 (0.68) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL69359 | 1.00 | CA12 (0.68) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL8084576 | 1.00 | CA12 (0.68) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL22462 | 0.97 | CA12 (0.71) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL20500514 | 0.97 | CA12 (0.71) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL28462260 | 0.97 | CA12 (0.71) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL2512374 | 0.97 | CA12 (0.71) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL147366 | 0.97 | CA12 (0.71) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL28756611 | 0.97 | CA12 (0.71) | CA12CA1CA2CA6CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110358081-B | Preparation method of aromatic polyamide high polymer containing sulfonic group and having higher molecular weight | 东华大学 | 2021-11-09 | — | — | CN | claimed |
| CN-112973473-A | Reverse osmosis composite membrane resisting biological pollution and preparation method thereof | 天津工业大学 | 2021-06-18 | — | — | CN | claimed |
| CN-117120504-A | Thermosetting resin composition, high-frequency device, dielectric substrate, and microstrip antenna | 住友电木株式会社 | 2023-11-24 | — | — | CN | disclosed |
| CN-117083345-A | Thermosetting resin composition, high-frequency device, dielectric substrate, and microstrip antenna | 住友电木株式会社 | 2023-11-17 | — | — | CN | disclosed |
| CN-113637210-B | Gas-barrier moisture-permeable film and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-04-04 | — | — | CN | disclosed |
| WO-2023286728-A1 | RESIN COMPOSITION FOR SEMICONDUCTOR SEALING, AND SEMICONDUCTOR DEVICE | 住友ベークライト株式会社 | 2023-01-19 | — | — | WO | disclosed |
| WO-2022202804-A1 | THERMOSETTING RESIN COMPOSITION, DIELECTRIC SUBSTRATE, AND MICROSTRIP ANTENNA | 住友ベークライト株式会社 | 2022-09-29 | — | — | WO | disclosed |
| WO-2022202792-A1 | THERMOSETTING RESIN COMPOSITION, HIGH-FREQUENCY DEVICE, DIELECTRIC SUBSTRATE, AND MICROSTRIP ANTENNA | 住友ベークライト株式会社 | 2022-09-29 | — | — | WO | disclosed |
| WO-2022202781-A1 | THERMOSETTING RESIN COMPOSITION, HIGH FREQUENCY DEVICE, DIELECTRIC SUBSTRATE, AND MICROSTRIP ANTENNA | 住友ベークライト株式会社 | 2022-09-29 | — | — | WO | disclosed |
| CN-113637210-A | Gas-barrier moisture-permeable film and preparation method and application thereof | 中国石油化工股份有限公司 | 2021-11-12 | — | — | CN | disclosed |
| CN-110358081-B | Preparation method of aromatic polyamide high polymer containing sulfonic group and having higher molecular weight | 东华大学 | 2021-11-09 | — | — | CN | disclosed |
| CN-106488946-B | Manufacturing method, stacked film and the spacer of aromatic polymer | 住友化学株式会社 | 2019-04-19 | — | — | CN | disclosed |
| CN-106488946-A | The manufacture method of aromatic polymer, stacked film and distance piece | 住友化学株式会社 | 2017-03-08 | — | — | CN | disclosed |
| CN-106459581-A | Polymer composition, laminated film, and separator | 住友化学株式会社 | 2017-02-22 | — | — | CN | disclosed |
| US-20070031663-A1 | Wholly aromatic polyamide fiber and process for producing the same | TEIJIN TECHNO PRODUCTS LIMITED (JP) | 2007-02-08 | — | — | US | disclosed |
| EP-1666648-A1 | WHOLLY AROMATIC POLYAMIDE FIBER AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 2006-06-07 | — | — | EP | disclosed |
| CN-1068582-C | Method for producing diacyl chlorides | FRUCTAMINE SPA (IT) | 2001-07-18 | — | — | CN | disclosed |
| US-5672735-A | 5-((ACETYLOXY)-1-OXOPROPYL)AMINO)-2,4,6-TRIIODO-1,3-BENZENEDI CARBONYL CHLORIDE BY REACTING 5-AMINO-2,4,6-TRIIODOBENZENE DICARBONYL CHLORIDE WITH THE PROPIONYL CHLORIDE COMPOUND USING AN APROTIC DIPOLAR SOLVENT AND HALOHYDRIC ACID CATALYST | FRUCTAMINE S.P.A. (IT) | 1997-09-30 | — | — | US | disclosed |
| CN-1154690-A | Method for prepn. of diacyl-chloride | FRUCTAMINE SPA (IT) | 1997-07-16 | — | — | CN | disclosed |
| US-4965134-A | Method for manufacturing highly heat-resistant dielectrics | SIEMENS AKTIENGESELLSCHAFT (DE) | 1990-10-23 | — | — | US | disclosed |