Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Octadecanoic Acid Amide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG known ✓ | P37231 | 4/20 | 0.45 |
| ▸ | HDAC11 known ✓ | Q96DB2 | 3/20 | 0.45 |
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.45 |
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.45 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetradecanamide SCHEMBL7129794 | 1.00 | SOAT1 (0.55) | SOAT1MEN1KMT2AFAAHTP53 | |
| Palmitamide SCHEMBL27844157 | 1.00 | SOAT1 (0.55) | SOAT1MEN1KMT2AFAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL1845513 | 0.98 | SOAT1 (0.57) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL28413906 | 0.98 | SOAT1 (0.57) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL29072296 | 0.98 | SOAT1 (0.57) | SOAT1MEN1KMT2AFAAHTP53 | |
| Tetradecanamide SCHEMBL4193813 | 0.98 | SOAT1 (0.57) | SOAT1MEN1KMT2AFAAHTP53 | |
| Palmitamide SCHEMBL2018663 | 0.98 | SOAT1 (0.57) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL29087884 | 0.98 | SOAT1 (0.57) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL28450507 | 0.98 | SOAT1 (0.57) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL29164254 | 0.98 | SOAT1 (0.57) | SOAT1MEN1KMT2AFAAHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1571765-B | Esters of aromatic alkoxylated alcohols and fatty carboxylic acids | CRODA INC | 2012-09-26 | — | — | CN | disclosed |
| US-20070233024-A1 | Sanitary Thin Paper and Process for Producing the Same | DAIO PAPER CORPORATION | 2007-10-04 | — | — | US | disclosed |
| EP-1752580-A1 | SANITARY THIN PAPER AND PROCESS FOR PRODUCING THE SAME | Daio Paper Corporation (JP) | 2007-02-14 | — | — | EP | disclosed |
| CN-1187014-C | Personal care articles comprising batting | PROCTER & GAMBLE (US) | 2005-02-02 | — | — | CN | disclosed |
| CN-1571765-A | Esters of aromatic alkoxylated alcohols and fatty carboxylic acids | CRODA INC (US) | 2005-01-26 | — | — | CN | disclosed |
| CN-1178620-C | Personal care articles | — | 2004-12-08 | — | — | CN | disclosed |
| CN-1420742-A | Personal care articles | PROCTER & GAMBLE (US) | 2003-05-28 | — | — | CN | disclosed |
| CN-1399524-A | Personal care article comprising cotton layer | PROCTER & GAMBLE (US) | 2003-02-26 | — | — | CN | disclosed |
| CN-1377240-A | Personal care articles | PROCTER & GAMBLE (US) | 2002-10-30 | — | — | CN | disclosed |
| CN-1079665-C | Personal cleansing compositions | PROCTER & GAMBLE (US) | 2002-02-27 | — | — | CN | disclosed |
| CN-1130864-A | Personal cleansing compositions | PROCTER & GAMBLE (US) | 1996-09-11 | — | — | CN | disclosed |