Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 known ✓ | O95136 | 5/20 | 0.59 |
| ▸ | S1PR1 known ✓ | P21453 | 5/20 | 0.59 |
| ▸ | S1PR3 known ✓ | Q99500 | 5/20 | 0.59 |
| ▸ | S1PR4 known ✓ | O95977 | 4/20 | 0.59 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.57 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.60 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.60 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29131326 | 1.00 | PLA2G1B (0.60) | PLA2G1BPLA2G2AS1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL9133431 | 1.00 | PLA2G1B (0.60) | PLA2G1BPLA2G2AS1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL3837898 | 1.00 | PLA2G1B (0.60) | PLA2G1BPLA2G2AS1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL28525593 | 1.00 | PLA2G1B (0.60) | PLA2G1BPLA2G2AS1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL565333 | 1.00 | PLA2G1B (0.60) | PLA2G1BPLA2G2AS1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL5547432 | 1.00 | PLA2G1B (0.60) | PLA2G1BPLA2G2AS1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL23496017 | 1.00 | PLA2G1B (0.60) | PLA2G1BPLA2G2AS1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL321031 | 1.00 | PLA2G1B (0.60) | PLA2G1BPLA2G2AS1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL2698937 | 1.00 | PLA2G1B (0.60) | PLA2G1BPLA2G2AS1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL10422267 | 1.00 | PLA2G1B (0.60) | PLA2G1BPLA2G2AS1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111698982-B | Hair treatment composition | 株式会社资生堂 | 2024-09-27 | — | — | CN | disclosed |
| CN-111373000-B | Resin composition containing fibrous cellulose, sheet and molded body | 王子控股株式会社 | 2022-02-25 | — | — | CN | disclosed |
| CN-111373000-A | Resin composition containing fibrous cellulose, sheet and molded body | 王子控股株式会社 | 2020-07-03 | — | — | CN | disclosed |
| CN-111246821-A | Light absorbing compositions and methods of use | 美国绿阳生物技术及医药公司 | 2020-06-05 | — | — | CN | disclosed |
| CN-105189531-B | Peptides for skin rejuvenation and methods of use thereof | 安特易斯有限公司 | 2020-02-21 | — | — | CN | disclosed |
| US-20070233024-A1 | Sanitary Thin Paper and Process for Producing the Same | DAIO PAPER CORPORATION | 2007-10-04 | — | — | US | disclosed |
| EP-1752580-A1 | SANITARY THIN PAPER AND PROCESS FOR PRODUCING THE SAME | Daio Paper Corporation (JP) | 2007-02-14 | — | — | EP | disclosed |
| EP-1051210-A2 | ENHANCED BIOCOMPATIBILITY COATINGS FOR MEDICAL IMPLANTS | Edwards Lifesciences Corporation (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999038547-A2 | ENHANCED BIOCOMPATIBILITY COATINGS FOR MEDICAL IMPLANTS | EDWARDS LIFESCIENCES CORPORATION (US) | 1999-08-05 | — | — | WO | disclosed |
| US-5306432-A | Synergistic combination of water-soluble quaternary ammonium compound and water-soluble oxidizing agent | GREAT LAKES BIOCHEMICAL CO., INC. (US) | 1994-04-26 | — | — | US | disclosed |
| US-4536349-A | Furan derivatives useful as aroma compounds | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1985-08-20 | — | — | US | disclosed |
| US-4367749-A | Nonthrombogenic articles and method of preparation | BECTON, DICKINSON & COMPANY (US) | 1983-01-11 | — | — | US | disclosed |
| US-4349467-A | HEPARIN SUBSTRATES | WILLIAMS JOEL L | 1982-09-14 | — | — | US | disclosed |
| US-4302368-A | AMINE SALT OF HEPARIN AFFIXED TO POLYMER | BECTON, DICKINSON AND COMPANY (US) | 1981-11-24 | — | — | US | disclosed |
| US-4230681-A | HEATING WITH A SOLVENT | CHEMISCHE WERKE HULS AG (DE) | 1980-10-28 | — | — | US | disclosed |
| US-4116898-A | POLYETHYLENE SUBSTRATE, HEPARIN SALT OF N-METHYLDODECYLAMINE | BECTON, DICKINSON AND COMPANY (US) | 1978-09-26 | — | — | US | disclosed |