Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pyrazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrazole SCHEMBL1559259 | 1.00 | — | — | |
| Pyrazole SCHEMBL23295201 | 1.00 | — | — | |
| Pyrazole SCHEMBL1800516 | 1.00 | — | — | |
| Pyrazole SCHEMBL30854861 | 0.96 | — | — | |
| Pyrazole SCHEMBL30626480 | 0.96 | — | — | |
| Pyrazole SCHEMBL7671561 | 0.96 | — | — | |
| Pyrazole SCHEMBL5664483 | 0.96 | — | — | |
| Pyrazole SCHEMBL1384 | 0.96 | — | — | |
| Pyrazole SCHEMBL1236436 | 0.94 | — | — | |
| Pyrazole SCHEMBL28302306 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739430-A1 | SORBENT MATERIALS FOR CO2 CAPTURE, USES THEREOF AND METHODS FOR MAKING SAME | Climeworks AG (CH) | 2026-05-13 | — | — | EP | claimed |
| WO-2025008318-A1 | SORBENT MATERIALS FOR CO2 CAPTURE, USES THEREOF AND METHODS FOR MAKING SAME | CLIMEWORKS AG (CH) | 2025-01-09 | — | — | WO | claimed |
| CN-117756721-A | Co-crystal of dibazoles and tartaric acid as well as preparation and application thereof | 浙江方锘制药有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-117430558-A | Preparation and application of drug-drug co-crystal of dibazol hydrochloride and atenolol and drug composition | 上海应用技术大学 | 2024-01-23 | — | — | CN | claimed |
| CN-117430557-A | Preparation and application of eutectic crystal form of dibazoles and mandelic acid and pharmaceutical composition | 上海应用技术大学 | 2024-01-23 | — | — | CN | claimed |
| CN-115105468-A | Dibazol eye drops and preparation method thereof | 四川禾亿制药有限公司 | 2022-09-27 | — | — | CN | claimed |
| CN-109962289-B | Electrolyte composition and metal ion battery comprising same | 财团法人工业技术研究院 | 2022-03-11 | — | — | CN | claimed |
| CN-112903833-A | High performance liquid chromatography analysis method for detecting organic impurities in dibazol | 山东博山制药有限公司 | 2021-06-04 | — | — | CN | claimed |
| CN-108863946-B | Preparation method of dibazole impurity reference substance | 武汉先路医药科技股份有限公司 | 2020-11-06 | — | — | CN | claimed |
| CN-111346050-A | Dibazol hydrochloride eye drops and preparation method thereof | 四川禾亿制药有限公司 | 2020-06-30 | — | — | CN | claimed |
| CN-102241737-A | Endomorphin-1 analogs, synthesis thereof and application of endomorphin-1 analogs in preparation of analgesic medicines | UNIV LANZHOU | 2011-11-16 | — | — | CN | claimed |
| CN-101910170-A | (1,4-diazabicyclo [3.2.2] ninth of the ten Heavenly Stems-6-alkene-4-yl)-heterocyclic radical-ketone part that is used for the treatment of the nicotinic acetylcholine receptor of disease | MEMORY PHARM CORP | 2010-12-08 | — | — | CN | claimed |
| CN-101906074-A | Preparation method of dibazol hydrochloride | ZHEJIANG MED XINCHANG PHARM | 2010-12-08 | — | — | CN | claimed |
| CN-101891688-A | Preparation method for bendazol in industrialized production | XIAOGAN CHENGJIA INST OF MATERIA MEDICA | 2010-11-24 | — | — | CN | claimed |
| CN-101134774-A | Combined chemical modified endomorphin-1 and method for preparing same | UNIV LANZHOU (CN) | 2008-03-05 | — | — | CN | claimed |
| CN-1134259-C | Use of tetrahydropyridine (or 4-hydropiperidine) butylpyrrole derivatives for the preparation of a medicament for the treatment of pain | ��˹���IJ�ʿʵ���ҹɷ�����˾ | 2004-01-14 | — | — | CN | claimed |
| WO-2003022233-A1 | AGENT FOR DYEING KERATIN FIBERS, CONTAINING A BLUE CATIONIC ANTHRAQUINONE DYE | WELLA AKTIENGESELLSCHAFT (DE) | 2003-03-20 | — | — | WO | claimed |
| CN-1314814-A | Utilization of derivatives of tetrahydropyridines (or 4-hydroxypiperdines)-butylazols in preparation of a medicament for the treamtent of pain | ESTEVE LABOR DR (ES) | 2001-09-26 | — | — | CN | claimed |
| WO-1999064425-A1 | SUBSTITUTED THIENOCYCLOALKYLPYRAZOLES: DOPAMINE RECEPTOR SUBTYPE SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 1999-12-16 | — | — | WO | claimed |
| US-4374744-A | AN ACID, OXIDIZER AND A HETEROCYCLIC COMPOUND | MEC CO., LTD. (JP) | 1983-02-22 | — | — | US | claimed |