Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Trimethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27548957 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL9550176 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL9550175 | 0.90 | — | — | |
| SCHEMBL4929733 | 0.87 | — | — | |
| SCHEMBL259145 | 0.87 | — | — | |
| SCHEMBL245654 | 0.87 | — | — | |
| Methane SCHEMBL11212900 | 0.83 | — | — | |
| SCHEMBL30074589 | 0.83 | — | — | |
| SCHEMBL2334958 | 0.83 | — | — | |
| Ethane SCHEMBL11209141 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230138358-A1 | COATED PARTICLES AND METHODS OF MAKING AND USING THE SAME | TETHIS, INC. | 2023-05-04 | — | — | US | disclosed |
| US-20230000696-A1 | ABSORBENT ARTICLES WITH BIOCOMPOSTABLE PROPERTIES | TETHIS, INC. (US) | 2023-01-05 | — | — | US | disclosed |
| CN-108779387-B | Coated particles and methods of making and using the same | 艾纳沃技术有限责任公司 | 2022-07-01 | — | — | CN | disclosed |
| US-20220031526-A1 | ABSORBENT ARTICLES WITH BIOCOMPOSTABLE PROPERTIES | TETHIS, INC. (US) | 2022-02-03 | — | — | US | disclosed |
| CN-113896913-A | Modified biopolymers and methods of making and using the same | 安诺华科技有限公司 | 2022-01-07 | — | — | CN | disclosed |
| US-11154436-B2 | Absorbent articles with biocompostable properties | TETHIS, INC. (US) | 2021-10-26 | — | — | US | disclosed |
| US-11090198-B2 | Absorbent articles with biocompostable properties | TETHIS, INC. (US) | 2021-08-17 | — | — | US | disclosed |
| US-20210244844-A1 | ABSORBENT ARTICLES WITH BIOCOMPOSTABLE PROPERTIES | TETHIS, INC. (US) | 2021-08-12 | — | — | US | disclosed |
| US-20210161732-A1 | ABSORBENT ARTICLES WITH BIOCOMPOSTABLE PROPERTIES | TETHIS, INC. (US) | 2021-06-03 | — | — | US | disclosed |
| US-20210161733-A1 | ABSORBENT ARTICLES WITH BIOCOMPOSTABLE PROPERTIES | TETHIS, INC. (US) | 2021-06-03 | — | — | US | disclosed |
| EP-0479826-B1 | CLEANING COMPOSITION | UNILEVER PLC (GB) | 1996-01-17 | — | — | EP | disclosed |
| US-5473059-A | Adding solvent to cationic water soluble quaternary ammonium ethers of polysaccharide of polysaccharide or polyols to form gels or liquids; used in personal care products | RHONE-POULENC INC. (US) | 1995-12-05 | — | — | US | disclosed |
| US-5387675-A | Water soluble quaternary ammonium ethers of polysaccharides or polyols | RHONE-POULENC SPECIALTY CHEMICALS CO. (US) | 1995-02-07 | — | — | US | disclosed |
| EP-0479826-A1 | CLEANING COMPOSITION. | UNILEVER PLC (GB) | 1992-04-15 | — | — | EP | disclosed |
| WO-1991000332-A1 | CLEANING COMPOSITION | UNILEVER PLC (GB) | 1991-01-10 | — | — | WO | disclosed |
| US-4237016-A | NONIONIC SOFTENING AGENT AND A POLYMERIC CATIONIC SALT | THE PROCTER & GAMBLE COMPANY (US) | 1980-12-02 | — | — | US | disclosed |
| US-4179382-A | SOFTENERS | THE PROCTER & GAMBLE COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
| EP-0002085-A2 | Textile conditioning compositions with low content of cationic guar gum | THE PROCTER & GAMBLE COMPANY (US) | 1979-05-30 | — | — | EP | disclosed |
| US-4011169-A | USING AN ENZYME AND AMINATED POLYSACCHARIDE | THE PROCTER & GAMBLE COMPANY (US) | 1977-03-08 | — | — | US | disclosed |
| US-3944470-A | AMINATED POLYSACCHARIDE | THE PROCTER & GAMBLE COMPANY (US) | 1976-03-16 | — | — | US | disclosed |