Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL110438 | 0.98 | — | — | |
| Chloromethane SCHEMBL19549280 | 0.94 | TSHR (0.52) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Sulfuric Acid SCHEMBL31207724 | 0.90 | TSHR (0.48) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Hydrochloric Acid SCHEMBL6053427 | 0.88 | TSHR (0.61) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL110329 | 0.86 | TSHR (0.63) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL21880085 | 0.86 | TSHR (0.44) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL8627253 | 0.86 | TSHR (0.44) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Hydrochloric Acid SCHEMBL28852507 | 0.85 | TSHR (0.68) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL113045 | 0.84 | TSHR (0.67) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL19333937 | 0.82 | TSHR (0.70) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924619-A | Preparation method of flocculant, product and application thereof | 中国石油化工股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117886410-A | Preparation method of hybrid flocculant, product and application thereof | 中国石油化工股份有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-113908703-B | Charged nanofiltration membrane based on polymer nanoparticles and preparation method thereof | 浙江大学 | 2023-01-10 | — | — | CN | claimed |
| CN-113856486-A | Charged composite nanofiltration membrane based on organic-inorganic nanoparticles and preparation method thereof | 浙江大学 | 2021-12-31 | — | — | CN | claimed |
| EP-3649203-A1 | ABSORBENT MATERIAL FOR PROTECTING ELECTRONIC DEVICES | Arkema France (FR) | 2020-05-13 | — | — | EP | claimed |
| US-20140054042-A1 | Centre For The Preparation Of Additives For Hydraulic Fracturing Operations And Hydraulic Fracturing Process Employing The Preparation Centre | S.P.C.M. SA (FR) | 2014-02-27 | — | — | US | claimed |
| CN-117924619-A | Preparation method of flocculant, product and application thereof | 中国石油化工股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117886410-A | Preparation method of hybrid flocculant, product and application thereof | 中国石油化工股份有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-115298110-B | Cover tape for packaging electronic component and package | 大日本印刷株式会社 | 2024-02-02 | — | — | CN | disclosed |
| CN-116693865-A | Grafting modified amphoteric polyacrylamide filtrate reducer, preparation method and application thereof | 爱森（中国）絮凝剂有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-115298110-A | Cover tape for packaging electronic component and package | 大日本印刷株式会社 | 2022-11-04 | — | — | CN | disclosed |
| CN-111253592-A | Photo-crosslinked gamma-polyglutamic acid hydrogel and preparation method and application thereof | 南京工业大学 | 2020-06-09 | — | — | CN | disclosed |
| EP-3649203-A1 | ABSORBENT MATERIAL FOR PROTECTING ELECTRONIC DEVICES | Arkema France (FR) | 2020-05-13 | — | — | EP | disclosed |
| EP-1276516-B1 | DURABLE, ABSORBENT LATEX FOAM COMPOSITION HAVING HIGH VERTICAL WICKING | DOW GLOBAL TECHNOLOGIES INC (US) | 2006-02-08 | — | — | EP | disclosed |
| US-6900249-B2 | Durable, absorbent latex foam composition having high vertical wicking | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-05-31 | — | — | US | disclosed |
| US-20030195266-A1 | Durable, absorbent latex foam composition having high vertical wicking | MORK STEVEN W (US) | 2003-10-16 | — | — | US | disclosed |
| US-6627670-B2 | Latex foam capable of acquiring and distributing aqueous fluids is prepared from one or more ethylenically unsaturated monomers selected from the group styrene monomers and monomers copolymerizable with styrene monomer | DOW GLOBAL TECHNOLOGIES INC. | 2003-09-30 | — | — | US | disclosed |
| EP-1276516-A2 | DURABLE, ABSORBENT LATEX FOAM COMPOSITION HAVING HIGH VERTICAL WICKING | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-01-22 | — | — | EP | disclosed |
| US-20020002209-A1 | Durable, absorbent latex foam composition having high vertical wicking | THE DOW CHEMICAL COMPANY | 2002-01-03 | — | — | US | disclosed |
| WO-2001080916-A2 | DURABLE, ABSORBENT LATEX FOAM COMPOSITION HAVING HIGH VERTICAL WICKING | THE DOW CHEMICAL COMPANY (US) | 2001-11-01 | — | — | WO | disclosed |