Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.60 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.60 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.60 |
| ▸ | HTR2C known ✓ | P28335 | 1/20 | 0.60 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.60 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.60 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.60 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.60 |
| ▸ | HDAC1 known ✓ | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC2 known ✓ | Q92769 | 1/20 | 0.60 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.44 |
| ▸ | LCK known ✓ | P06239 | 1/20 | 0.41 |
| ▸ | HDAC7 known ✓ | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC8 known ✓ | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 known ✓ | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 known ✓ | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 known ✓ | Q9UQL6 | 1/20 | 0.40 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28567577 | 1.00 | CHRM1 (0.60) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL31607 | 0.97 | HDAC1 (0.63) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL28315696 | 0.94 | CHRM1 (0.60) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL21295009 | 0.94 | CHRM1 (0.60) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL27308487 | 0.94 | CHRM1 (0.60) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL107766 | 0.94 | CHRM1 (0.60) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Calcium SCHEMBL6995406 | 0.94 | CHRM1 (0.60) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Water SCHEMBL27595106 | 0.94 | CHRM1 (0.60) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL28059342 | 0.94 | CHRM1 (0.60) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL28314489 | 0.94 | CHRM1 (0.60) | CHRM1AKR1A1CHRM3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4176962-B1 | COMPOSITE SEMIPERMEABLE MEMBRANE, SPIRAL MEMBRANE ELEMENT, WATER TREATMENT SYSTEM, AND WATER TREATMENT METHOD | NITTO DENKO CORP (JP) | 2026-01-28 | — | — | EP | disclosed |
| EP-4631607-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, AND SPIRAL-TYPE MEMBRANE ELEMENT | Nitto Denko Corporation (JP) | 2025-10-15 | — | — | EP | disclosed |
| EP-4424409-B1 | COMPOSITE SEMIPERMEABLE MEMBRANE, AND SPIRAL MEMBRANE ELEMENT | NITTO DENKO CORP (JP) | 2025-08-20 | — | — | EP | disclosed |
| EP-3682964-B1 | COMPOSITE SEMIPERMEABLE MEMBRANE AND METHOD FOR MANUFACTURING SAME | NITTO DENKO CORP (JP) | 2025-06-18 | — | — | EP | disclosed |
| US-12239942-B2 | Separation membrane | NITTO DENKO CORPORATION (JP) | 2025-03-04 | — | — | US | disclosed |
| US-20240293783-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, AND SPIRAL MEMBRANE ELEMENT | NITTO DENKO CORPORATION (JP) | 2024-09-05 | — | — | US | disclosed |
| EP-4424409-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, AND SPIRAL MEMBRANE ELEMENT | Nitto Denko Corporation (JP) | 2024-09-04 | — | — | EP | disclosed |
| EP-4389266-A1 | METHOD FOR PRESERVING COMPOSITE SEMIPERMEABLE MEMBRANE, PRESERVATION SOLUTION, AND SPIRAL MEMBRANE ELEMENT | Nitto Denko Corporation (JP) | 2024-06-26 | — | — | EP | disclosed |
| US-20240198292-A1 | METHOD FOR PRESERVING COMPOSITE SEMIPERMEABLE MEMBRANE, PRESERVATION SOLUTION, AND SPIRAL MEMBRANE ELEMENT | NITTO DENKO CORPORATION (JP) | 2024-06-20 | — | — | US | disclosed |
| WO-2024122107-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, AND SPIRAL-TYPE MEMBRANE ELEMENT | 日東電工株式会社 | 2024-06-13 | — | — | WO | disclosed |
| US-20100044902-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE AND PROCESS FOR PRODUCING THE SAME | OHARA TOMOMI | 2010-02-25 | — | — | US | disclosed |
| US-20080277334-A1 | Process for Producing Semipermeable Composite Membrane | NITTO DENKO CORPORATION (JP) | 2008-11-13 | — | — | US | disclosed |
| US-20080257818-A1 | Semipermeable Composite Membrane and Process for Producing the Same | NITTO DENKO CORPORATION (JP) | 2008-10-23 | — | — | US | disclosed |
| US-20080251447-A1 | PROCESS FOR PRODUCING A DRIED COMPOSITE SEMIPERMEABLE MEMBRANE | NITTO DENKO CORPORATION (JP) | 2008-10-16 | — | — | US | disclosed |
| US-20080083670-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE AND PROCESS FOR PRODUCING THE SAME | NITTO DENKO CORPORATION (JP) | 2008-04-10 | — | — | US | disclosed |
| US-20080053893-A1 | Semipermeable Composite Membrane and Process for Producing the Same | NITTO DENKO CORPORATION (JP) | 2008-03-06 | — | — | US | disclosed |
| EP-1825905-A1 | SEMIPERMEABLE COMPOSITE MEMBRANE AND PROCESS FOR PRODUCING THE SAME | Nitto Denko Corporation (JP) | 2007-08-29 | — | — | EP | disclosed |
| EP-1820566-A1 | SEMIPERMEABLE COMPOSITE MEMBRANE AND PROCESS FOR PRODUCING THE SAME | Nitto Denko Corporation (JP) | 2007-08-22 | — | — | EP | disclosed |
| EP-1806174-A1 | PROCESS FOR PRODUCING SEMIPERMEABLE COMPOSITE MEMBRANE | Nitto Denko Corporation (JP) | 2007-07-11 | — | — | EP | disclosed |
| US-4316022-A | Benzo-as-triazine derivatives | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1982-02-16 | — | — | US | disclosed |