Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 known ✓ | P28845 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 6/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GRM8 | O00222 | 2/20 | 0.35 |
| ▸ | GRM6 | O15303 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2494923 | 1.00 | CYP2C19 (0.39) | CYP2C19GRM4CYP1A2GRM2GRM3 | |
| Hydrochloric Acid SCHEMBL28459632 | 1.00 | CYP2C19 (0.39) | CYP2C19GRM4CYP1A2GRM2GRM3 | |
| SCHEMBL38190 | 0.98 | CYP2C19 (0.40) | CYP2C19GRM4CYP1A2GRM2GRM3 | |
| SCHEMBL27615428 | 0.96 | CYP2C19 (0.39) | CYP2C19GRM4CYP1A2GRM2GRM3 | |
| SCHEMBL11263069 | 0.96 | CYP2C19 (0.43) | CYP2C19GRM4CYP1A2GRM2GRM3 | |
| Cyclohexane SCHEMBL28031962 | 0.96 | CYP2C19 (0.43) | CYP2C19GRM4CYP1A2GRM2GRM3 | |
| Hydrochloric Acid SCHEMBL25405452 | 0.93 | GRM4 (0.36) | CYP2C19GRM4CYP1A2GRM2GRM3 | |
| Hydrochloric Acid SCHEMBL3267782 | 0.93 | GRM4 (0.36) | CYP2C19GRM4CYP1A2GRM2GRM3 | |
| Hydrochloric Acid SCHEMBL628181 | 0.93 | GRM4 (0.36) | CYP2C19GRM4CYP1A2GRM2GRM3 | |
| Hydrochloric Acid SCHEMBL28445038 | 0.93 | GRM4 (0.36) | CYP2C19GRM4CYP1A2GRM2GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4176962-B1 | COMPOSITE SEMIPERMEABLE MEMBRANE, SPIRAL MEMBRANE ELEMENT, WATER TREATMENT SYSTEM, AND WATER TREATMENT METHOD | NITTO DENKO CORP (JP) | 2026-01-28 | — | — | EP | disclosed |
| EP-4631607-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, AND SPIRAL-TYPE MEMBRANE ELEMENT | Nitto Denko Corporation (JP) | 2025-10-15 | — | — | EP | disclosed |
| EP-4424409-B1 | COMPOSITE SEMIPERMEABLE MEMBRANE, AND SPIRAL MEMBRANE ELEMENT | NITTO DENKO CORP (JP) | 2025-08-20 | — | — | EP | disclosed |
| EP-3682964-B1 | COMPOSITE SEMIPERMEABLE MEMBRANE AND METHOD FOR MANUFACTURING SAME | NITTO DENKO CORP (JP) | 2025-06-18 | — | — | EP | disclosed |
| US-12239942-B2 | Separation membrane | NITTO DENKO CORPORATION (JP) | 2025-03-04 | — | — | US | disclosed |
| US-20240293783-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, AND SPIRAL MEMBRANE ELEMENT | NITTO DENKO CORPORATION (JP) | 2024-09-05 | — | — | US | disclosed |
| EP-4424409-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, AND SPIRAL MEMBRANE ELEMENT | Nitto Denko Corporation (JP) | 2024-09-04 | — | — | EP | disclosed |
| EP-4389266-A1 | METHOD FOR PRESERVING COMPOSITE SEMIPERMEABLE MEMBRANE, PRESERVATION SOLUTION, AND SPIRAL MEMBRANE ELEMENT | Nitto Denko Corporation (JP) | 2024-06-26 | — | — | EP | disclosed |
| US-20240198292-A1 | METHOD FOR PRESERVING COMPOSITE SEMIPERMEABLE MEMBRANE, PRESERVATION SOLUTION, AND SPIRAL MEMBRANE ELEMENT | NITTO DENKO CORPORATION (JP) | 2024-06-20 | — | — | US | disclosed |
| WO-2024122107-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, AND SPIRAL-TYPE MEMBRANE ELEMENT | 日東電工株式会社 | 2024-06-13 | — | — | WO | disclosed |
| US-20080277334-A1 | Process for Producing Semipermeable Composite Membrane | NITTO DENKO CORPORATION (JP) | 2008-11-13 | — | — | US | disclosed |
| US-20080257818-A1 | Semipermeable Composite Membrane and Process for Producing the Same | NITTO DENKO CORPORATION (JP) | 2008-10-23 | — | — | US | disclosed |
| US-20080251447-A1 | PROCESS FOR PRODUCING A DRIED COMPOSITE SEMIPERMEABLE MEMBRANE | NITTO DENKO CORPORATION (JP) | 2008-10-16 | — | — | US | disclosed |
| US-20080083670-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE AND PROCESS FOR PRODUCING THE SAME | NITTO DENKO CORPORATION (JP) | 2008-04-10 | — | — | US | disclosed |
| US-20080053893-A1 | Semipermeable Composite Membrane and Process for Producing the Same | NITTO DENKO CORPORATION (JP) | 2008-03-06 | — | — | US | disclosed |
| EP-1825905-A1 | SEMIPERMEABLE COMPOSITE MEMBRANE AND PROCESS FOR PRODUCING THE SAME | Nitto Denko Corporation (JP) | 2007-08-29 | — | — | EP | disclosed |
| EP-1820566-A1 | SEMIPERMEABLE COMPOSITE MEMBRANE AND PROCESS FOR PRODUCING THE SAME | Nitto Denko Corporation (JP) | 2007-08-22 | — | — | EP | disclosed |
| EP-1808220-A1 | PROCESS FOR PRODUCING COMPOSITE REVERSE OSMOSIS MEMBRANE | Nitto Denko Corporation (JP) | 2007-07-18 | — | — | EP | disclosed |
| EP-1806174-A1 | PROCESS FOR PRODUCING SEMIPERMEABLE COMPOSITE MEMBRANE | Nitto Denko Corporation (JP) | 2007-07-11 | — | — | EP | disclosed |
| EP-1803758-A1 | POLYEPOXY COMPOUND, METHOD FOR PRODUCING SAME, THERMOSETTING RESIN COMPOSITION CONTAINING SAME, CURED PRODUCT OF SUCH COMPOSITION, AND METHOD FOR REMOVING SUCH CURED PRODUCT | KANSAI PAINT CO., LTD. (JP) | 2007-07-04 | — | — | EP | disclosed |