Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Methane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL11124378 | 1.00 | — | — | |
| Methane SCHEMBL9874326 | 1.00 | — | — | |
| Methane SCHEMBL28425981 | 1.00 | — | — | |
| Methane SCHEMBL9874331 | 1.00 | — | — | |
| Methane SCHEMBL8758902 | 1.00 | — | — | |
| Methane SCHEMBL3108868 | 1.00 | — | — | |
| Methane SCHEMBL3114454 | 1.00 | — | — | |
| Methane SCHEMBL28731327 | 0.87 | — | — | |
| Methane SCHEMBL23120099 | 0.82 | — | — | |
| Methane SCHEMBL1856821 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9546237-B2 | Stabilization of polymers that contain a hydrolyzable functionality | BRIDGESTONE CORPORATION (JP) | 2017-01-17 | — | — | US | claimed |
| WO-2005058861-A1 | PROCESS FOR PREPARING SIMVASTATIN. | UK CHEMIPHARM CO., LTD. (KR) | 2005-06-30 | — | — | WO | claimed |
| EP-1343732-A2 | HYDROPHOBIC, ANTI-MICROBIAL INSULATION PRODUCTS AND A HYDROPHOBIC, ANTI-MICROBIAL COATING COMPOSITION FOR PREPARING THE SAME | SAINT-GOBAIN ISOVER (FR) | 2003-09-17 | — | — | EP | claimed |
| US-20030064224-A1 | Hydrophobic, anti-microbial insulation products and a hydrophobic, anti-microbial coating composition for preparing the same | CERTAINTEED CORPORATION | 2003-04-03 | — | — | US | claimed |
| US-20020127399-A1 | Hydrophobic, anti-microbial insulation products and a hydrophobic, anti-microbial coating composition for preparing the same | CERTAINTEED CORPORATION (US) | 2002-09-12 | — | — | US | claimed |
| WO-2002049981-A2 | HYDROPHOBIC, ANTI-MICROBIAL INSULATION PRODUCTS AND A HYDROPHOBIC, ANTI-MICROBIAL COATING COMPOSITION FOR PREPARING THE SAME | SAINT-GOBAIN ISOVER (FR) | 2002-06-27 | — | — | WO | claimed |
| EP-2658877-B1 | STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY | BRIDGESTONE CORP (JP) | 2023-04-12 | — | — | EP | disclosed |
| US-20200325036-A1 | HETEROGENEOUS WET SYNTHESIS PROCESS FOR PREPARATION OF HIGH PURITY TUNGSTEN PENTAHALIDE | AIR LIQUIDE (FR) | 2020-10-15 | — | — | US | disclosed |
| US-10669160-B2 | Heterogeneous wet synthesis process for preparation of high purity tungsten pentahalide | L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude (FR) | 2020-06-02 | — | — | US | disclosed |
| US-20190330076-A1 | HETEROGENEOUS WET SYNTHESIS PROCESS FOR PREPARATION OF HIGH PURITY TUNGSTEN PENTAHALIDE | L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude (FR) | 2019-10-31 | — | — | US | disclosed |
| US-9546237-B2 | Stabilization of polymers that contain a hydrolyzable functionality | BRIDGESTONE CORPORATION (JP) | 2017-01-17 | — | — | US | disclosed |
| US-9499683-B2 | Stabilization of polymers that contain a hydrolyzable functionality | BRIDGESTONE CORPORATION (JP) | 2016-11-22 | — | — | US | disclosed |
| US-20140031471-A1 | Stabilization Of Polymers That Contain A Hydrolyzable Functionality | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |
| CN-102573856-A | Method for preparing microRNA and therapeutic application thereof | FLEMMING VELIN | 2012-07-11 | — | — | CN | disclosed |
| WO-2012092626-A1 | STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY | BRIDGESTONE CORPORATION (JP) | 2012-07-05 | — | — | WO | disclosed |
| WO-2005058861-A1 | PROCESS FOR PREPARING SIMVASTATIN. | UK CHEMIPHARM CO., LTD. (KR) | 2005-06-30 | — | — | WO | disclosed |
| US-4405803-A | Process for the preparation of silylisocyanates | BAYER AKTIENGESELLSCHAFT (DE) | 1983-09-20 | — | — | US | disclosed |
| US-4232151-A | ANTIBIOTICS | SHIONOGI & CO., LTD. (JP) | 1980-11-04 | — | — | US | disclosed |
| US-4085090-A | Aromatic polymers containing a nitrogen-containing ring group, and process for preparation thereof | TEIJIN LIMITED (JA) | 1978-04-18 | — | — | US | disclosed |
| US-3943123-A | ANTIBIOTIC | KONINKLIJKE NEDERLANDSCHE GIST-EN SPIRITUSFABRIEK N.V. (NL) | 1976-03-09 | — | — | US | disclosed |