Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24344 | 0.87 | — | — | |
| SCHEMBL28502998 | 0.87 | — | — | |
| SCHEMBL23702405 | 0.75 | — | — | |
| SCHEMBL17442495 | 0.75 | — | — | |
| Water SCHEMBL29078557 | 0.75 | — | — | |
| SCHEMBL23275596 | 0.75 | — | — | |
| SCHEMBL5395693 | 0.75 | — | — | |
| SCHEMBL19858520 | 0.75 | — | — | |
| Water SCHEMBL15737877 | 0.75 | — | — | |
| SCHEMBL28834618 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105482002-B | Catalytic component, catalyst for vinyl polymerization and preparation method thereof | 中国石油化工股份有限公司 | 2018-03-02 | — | — | CN | disclosed |
| CN-105622802-B | Catalytic component, catalyst for ethylene polymerization and preparation method thereof | 中国石油化工股份有限公司 | 2017-12-19 | — | — | CN | disclosed |
| CN-105622802-A | Catalyst component for ethylene polymerization reaction, catalyst, and preparation method of catalyst component | CHINA PETROLEUM & CHEM CORP | 2016-06-01 | — | — | CN | disclosed |
| CN-105482002-A | Catalyst component for polymerization of ethylene, catalyst and preparation method of catalyst component | CHINA PETROLEUM & CHEM CORP | 2016-04-13 | — | — | CN | disclosed |
| US-20130158215-A1 | MODIFIED ZIEGLER-NATTA CATALYST SYSTEMS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2013-06-20 | — | — | US | disclosed |
| EP-2576641-A1 | MODIFIED ZIEGLER-NATTA CATALYST SYSTEMS | Total Research & Technology Feluy (BE) | 2013-04-10 | — | — | EP | disclosed |
| CN-103025772-A | Modified ziegler-natta catalyst systems | TOTAL PETROCHEMICALS RES FELUY | 2013-04-03 | — | — | CN | disclosed |
| WO-2011147733-A1 | MODIFIED ZIEGLER-NATTA CATALYST SYSTEMS | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2011-12-01 | — | — | WO | disclosed |
| EP-0809672-B1 | SILANE, FREE RADICAL GENERATOR, AMINE BLENDS FOR CROSSLINKING OF OLEFIN POLYMERS | GEN ELECTRIC (US) | 2004-06-23 | — | — | EP | disclosed |
| US-5981674-A | OLEFINICALLY UNSATURATED SILANE, HINDERED AMINE LIGHT STABILIZER COMPOUND, FREE RADICAL GENERATOR | WITCO CORPORATION (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0390153-A2 | Polymer compositions stabilized with polydialkylsiloxanes containing siloxy units having certain defined pendant sterically hindered phenol moieties | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) | 1990-10-03 | — | — | EP | disclosed |
| US-4960810-A | Polymer compositions stabilized with polydialkylsiloxanes containing siloxy units having certain defined pendant sterically hindered phenol moieties | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) | 1990-10-02 | — | — | US | disclosed |
| US-4931492-A | STABILITY AND OPTICAL PROPERTIES; BLENDS OF ETHYLENE HOMO-OR COPOLYMERS AND HYDROXY-FUNCTIONAL SILOXANES | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) | 1990-06-05 | — | — | US | disclosed |
| US-4925890-A | SILICONE, ORGANOPHOSPHORUS PROCESSING AID | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) | 1990-05-15 | — | — | US | disclosed |
| EP-0358200-A2 | Polymer compositions stabilized with polysiloxanes containing sterically hindered heterocyclic moiety | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (a New York corporation) (US) | 1990-03-14 | — | — | EP | disclosed |
| US-4895885-A | PHOTOSTABILITY | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) | 1990-01-23 | — | — | US | disclosed |
| EP-0335407-A2 | Polyolefin compositions containing polyorganosiloxanes and the use thereof in the production of film material | UNION CARBIDE CORPORATION (US) | 1989-10-04 | — | — | EP | disclosed |
| US-4857593-A | Process for processing thermoplastic polymers | UNION CARBIDE CORPORATION (US) | 1989-08-15 | — | — | US | disclosed |
| EP-0158140-A2 | Olefin polymer compositions containing silicone additives and the use thereof in the production of film material | UNION CARBIDE CORPORATION (US) | 1985-10-16 | — | — | EP | disclosed |
| US-4535113-A | IMPROVED MECHANICAL AND OPTICAL PROPERTIES | UNION CARBIDE CORPORATION (US) | 1985-08-13 | — | — | US | disclosed |