Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL182292 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL27917473 | 0.80 | GAA (0.62) | — | |
| SCHEMBL28014139 | 0.79 | — | — | |
| SCHEMBL15382664 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL394409 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL28994072 | 0.77 | GAA (0.52) | — | |
| SCHEMBL23561304 | 0.77 | GAA (0.65) | — | |
| SCHEMBL391332 | 0.77 | GAA (0.65) | — | |
| Hydrochloric Acid SCHEMBL2816887 | 0.77 | — | — | |
| Malonic Acid Diethyl Ester SCHEMBL356490 | 0.76 | GAA (0.94) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 772 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854630-A | Methods and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections | 吉利德科学公司 | 2023-10-10 | — | — | CN | claimed |
| CN-113214673-B | Glycoprotein-bound membrane dye based on pyrazolone, and preparation method and application thereof | 大连理工大学 | 2022-04-05 | — | — | CN | claimed |
| CN-110845356-B | Synthesis method of hydrazino ethyl acetate hydrochloride | 苏州永健生物医药有限公司 | 2022-03-04 | — | — | CN | claimed |
| CN-113214673-A | Glycoprotein-bound membrane dye based on pyrazolone, and preparation method and application thereof | 大连理工大学 | 2021-08-06 | — | — | CN | claimed |
| CN-109111371-B | Preparation method of hydrazino ethyl acetate hydrochloride | 江西万里药业有限公司 | 2021-08-06 | — | — | CN | claimed |
| EP-3752496-A1 | METHODS AND INTERMEDIATES FOR PREPARING A THERAPEUTIC COMPOUND USEFUL IN THE TREATMENT OF RETROVIRIDAE VIRAL INFECTION | GILEAD SCIENCES, INC. (US) | 2020-12-23 | — | — | EP | claimed |
| CN-110845356-A | Synthesis method of hydrazino ethyl acetate hydrochloride | 苏州永健生物医药有限公司 | 2020-02-28 | — | — | CN | claimed |
| WO-2019161280-A1 | METHODS AND INTERMEDIATES FOR PREPARING A THERAPEUTIC COMPOUND USEFUL IN THE TREATMENT OF RETROVIRIDAE VIRAL INFECTION | GILEAD SCIENCES, INC. (US) | 2019-08-22 | — | — | WO | claimed |
| CN-101304982-B | Process for the preparation of benzotriazepine derivatives | JANSSEN PHARMACEUTICA NV | 2013-03-13 | — | — | CN | claimed |
| CN-102311362-A | Method for preparing ethyl hydrazinoacetate hydrochloride | GUO CHENG | 2012-01-11 | — | — | CN | claimed |
| CN-101003494-B | Method for preparing diazanyl ethyl acetate hydrochloride | SHANGHAI CHEMICAL REAGENT RES INST | 2011-07-20 | — | — | CN | claimed |
| CN-101823982-A | Method for preparing hydrazine ethyl acetate hydrochloride | JIANGSU GRANDCHEM INDUSTRY CO LTD | 2010-09-08 | — | — | CN | claimed |
| CN-100478328-C | Process for preparing diazanyl ethyl acetate hydrochloride | SHANGHAI CHEMICAL REAGENT RES (CN) | 2009-04-15 | — | — | CN | claimed |
| CN-101304982-A | Process for the preparation of benzotriazepine derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2008-11-12 | — | — | CN | claimed |
| CN-101003494-A | Method for preparing diazanyl ethyl acetate hydrochloride | SHANGHAI INST OF CHEMICAL AGEN (CN) | 2007-07-25 | — | — | CN | claimed |
| CN-1721394-A | Process for preparing diazanyl ethyl acetate hydrochloride | SHANGHAI CHEMICAL REAGENT RES (CN) | 2006-01-18 | — | — | CN | claimed |
| WO-1988009823-A1 | AMINE DERIVATIVES OF ANTHRACYCLINE ANTIBIOTICS AND ANTIBODY CONJUGATES THEREOF | CYTOGEN CORPORATION (US) | 1988-12-15 | — | — | WO | claimed |
| EP-0294294-A2 | Amine derivatives of anthracycline antibiotics | CYTOGEN CORPORATION (US) | 1988-12-07 | — | — | EP | claimed |
| US-12636279-B2 | Choline salt forms of an HIV capsid inhibitor | GILEAD SCIENCES, INC. (US) | 2026-05-26 | — | — | US | disclosed |
| US-4101658-A | Antibacterial hydrazono cephalosporins | SHIONOGI & CO., LTD. (JP) | 1978-07-18 | — | — | US | disclosed |