Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 5/20 | 0.44 |
| ▸ | KCNH2 known ✓ | Q12809 | 2/20 | 0.42 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.42 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.42 |
| ▸ | OPRK1 known ✓ | P41145 | 1/20 | 0.42 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.42 |
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.41 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.41 |
| ▸ | MMP1 known ✓ | P03956 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1764642 | 1.00 | CSNK1E (0.53) | CSNK1ESIGMAR1KCNH2ADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL27519729 | 1.00 | CSNK1E (0.53) | CSNK1ESIGMAR1KCNH2ADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL3413577 | 1.00 | CSNK1E (0.53) | CSNK1ESIGMAR1KCNH2ADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL1416573 | 1.00 | CSNK1E (0.53) | CSNK1ESIGMAR1KCNH2ADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL5091454 | 1.00 | CSNK1E (0.53) | CSNK1ESIGMAR1KCNH2ADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL3294578 | 1.00 | CSNK1E (0.53) | CSNK1ESIGMAR1KCNH2ADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL7810565 | 1.00 | CSNK1E (0.53) | CSNK1ESIGMAR1KCNH2ADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL3409193 | 1.00 | CSNK1E (0.53) | CSNK1ESIGMAR1KCNH2ADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL8071028 | 0.98 | CSNK1E (0.51) | CSNK1ESIGMAR1KCNH2ADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL4927045 | 0.98 | CSNK1E (0.51) | CSNK1ESIGMAR1KCNH2ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907527-B | Water-based fracturing fluid thickening agent and preparation method thereof | 山东诺尔生物科技有限公司 | 2022-09-13 | — | — | CN | claimed |
| CN-114907527-A | Water-based fracturing fluid thickening agent and preparation method thereof | 山东诺尔生物科技有限公司 | 2022-08-16 | — | — | CN | claimed |
| US-11300555-B2 | Methods of analyzing crude oil | PURDUE RESEARCH FOUNDATION (US) | 2022-04-12 | — | — | US | claimed |
| WO-2022026968-A1 | SEPARATION MEMBRANE AND METHODS OF PREPARATION THEREOF | ASPEN PRODUCTS GROUP, INC. (US) | 2022-02-03 | — | — | WO | claimed |
| US-20220032240-A1 | Separation Membrane and Methods of Preparation Thereof | ASPEN PRODUCTS GROUP, INC. (US) | 2022-02-03 | — | — | US | claimed |
| CN-110695368-B | Eight-fork gold nano-particle, preparation method, application and intermediate thereof | 吉林大学 | 2022-01-07 | — | — | CN | claimed |
| CN-109986072-B | Four-fork gold nano-particle, preparation method and application thereof | 吉林大学 | 2021-06-25 | — | — | CN | claimed |
| CN-110386988-B | Modified starch and preparation method and application thereof | 瑞辰星生物技术（广州）有限公司 | 2021-06-04 | — | — | CN | claimed |
| CN-110387761-B | Method for recovering free starch in papermaking white water | 瑞辰星生物技术（广州）有限公司 | 2021-02-19 | — | — | CN | claimed |
| US-20210008526-A1 | METHOD | POLYCATUK LTD. (GB) | 2021-01-14 | — | — | US | claimed |
| WO-2019201221-A1 | MODIFIED STARCH AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 瑞辰星生物技术（广州）有限公司 | 2019-10-24 | — | — | WO | claimed |
| US-20190137473-A1 | METHODS OF ANALYZING CRUDE OIL | PURDUE RESEARCH FOUNDATION | 2019-05-09 | — | — | US | claimed |
| US-10197547-B2 | Methods of analyzing crude oil | PURDUE RESEARCH FOUNDATION (US) | 2019-02-05 | — | — | US | claimed |
| US-20170343526-A1 | METHODS OF ANALYZING CRUDE OIL | PURDUE RESEARCH FOUNDATION | 2017-11-30 | — | — | US | claimed |
| US-9733228-B2 | Methods of analyzing crude oil | PURDUE RESEARCH FOUNDATION (US) | 2017-08-15 | — | — | US | claimed |
| US-20150309001-A1 | METHODS OF ANALYZING CRUDE OIL | PURDUE RESEARCH FOUNDATION (US) | 2015-10-29 | — | — | US | claimed |
| WO-2014120552-A1 | METHODS OF ANALYZING CRUDE OIL | PURDUE RESEARCH FOUNDATION (US) | 2014-08-07 | — | — | WO | claimed |
| WO-2011101857-A2 | MULTIFUNCTIONAL TEXTILE | KHANDELWAL, SANJEEV (IN) | 2011-08-25 | — | — | WO | claimed |
| EP-0075524-B1 | CARBONYLATION PROCESS OF CONJUGATED DIENES IN THE PRESENCE OF A PALLADIUM CATALYST WITH RECYCLING OF SAID CATALYST | RHONE-POULENC CHIMIE DE BASE (FR) | 1984-09-12 | — | — | EP | claimed |
| US-4454333-A | DISTILLATION WITH QUATERNARY PHOSPHONIUM, ARSONIUM OR AMMONIUM | RHONE-POULENC CHIMIE DE BASE (FR) | 1984-06-12 | — | — | US | claimed |