Hydrazine

Hydrazine

SCHEMBL749536

Cl.NN.O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrazine SCHEMBL1193652 1.00
Hydrazine SCHEMBL28706989 1.00
Hydrazine SCHEMBL28744471 1.00
Hydrazine SCHEMBL11031699 1.00
Hydrazine SCHEMBL9780330 0.89
Hydrazine SCHEMBL4307 0.87
Hydrazine SCHEMBL1639413 0.87
Hydrazine SCHEMBL6849117 0.87
Hydrazine SCHEMBL21541663 0.87
Hydrazine SCHEMBL14860255 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116082317-B Selenium-containing coumarin derivative, preparation method thereof and application thereof in preparation of antitumor drugs 浙江工业大学 2025-04-15 CN claimed
CN-119707840-A Synthesis method of 1,2, 4-triazole 西安近代化学研究所 2025-03-28 CN claimed
CN-119725585-A Preparation method of platinum-carbon catalyst 苏州铂氢新能源科技有限公司 2025-03-28 CN claimed
US-20240376087-A1 PYRAZOLE AMIDE BASED COMPOUNDS AND USES AGAINST BREAST CANCER THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) 2024-11-14 US claimed
EP-4433173-A1 PYRAZOLE AMIDE BASED COMPOUNDS AND USES AGAINST BREAST CANCER THEREOF Council of Scientific and Industrial Research, an Indian Registered Body Incorporated under Regn. of Soc. Act (Act XXI of 1860) (IN) 2024-09-25 EP claimed
CN-118043310-A Pyrazole amide-based compounds and their use against breast cancer 科学与工业研究会(按照印度社会团体注册法案(1860年第21号法案)设立的注册机构) 2024-05-14 CN claimed
CN-117003642-A Synthesis method of Ensitrelvir key intermediate 上海璨谊生物科技有限公司 2023-11-07 CN claimed
CN-116337855-A Method for rapidly determining biological effective state heavy metals in soil by using smart phone colorimetric method 南京大学 2023-06-27 CN claimed
WO-2023089632-A1 PYRAZOLE AMIDE BASED COMPOUNDS AND USES AGAINST BREAST CANCER THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) 2023-05-25 WO claimed
CN-116082317-A Selenium-containing coumarin derivative, preparation method thereof and application thereof in preparation of antitumor drugs 浙江工业大学 2023-05-09 CN claimed
US-20110077271-A1 Process for the Preparation of Donepezil Hydrochloride CIPLA LIMITED (IN) 2011-03-31 US claimed
EP-2285770-A1 PROCESS FOR THE SYNTHESIS OF ARFORMOTEROL Cipla Limited (IN) 2011-02-23 EP claimed
EP-2278970-A1 PROCESS FOR THE PREPARATION OF DONEPEZIL HYDROCHLORIDE Cipla Limited (IN) 2011-02-02 EP claimed
CN-101683974-A Method for recycling rare hydrazine NANTONG RUIHONG BIOCHEMICAL CO 2010-03-31 CN claimed
WO-2009147383-A1 PROCESS FOR THE SYNTHESIS OF ARFORMOTEROL CIPLA LIMITED (IN) 2009-12-10 WO claimed
WO-2009118516-A1 PROCESS FOR THE PREPARATION OF DONEPEZIL HYDROCHLORIDE CIPLA LIMITED (GB) 2009-10-01 WO claimed
CN-100519556-C Method of synthesizing Itraconazole TIANJIN LISHENG PHARMACEUTICAL (CN) 2009-07-29 CN claimed
CN-1033691-C Neutral scaling powder for soldering tin core ZHOU JUNZHI (CN) 1997-01-01 CN claimed
CN-1110204-A Neutral scaling powder for soldering tin core ZHOU JUNZHI (CN) 1995-10-18 CN claimed
US-5011608-A Biogenic amine assay using HPLC-ECD DAMJANOVIC DRAGANA (CA) 1991-04-30 US claimed