Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3338400 | 0.97 | — | — | |
| SCHEMBL4609332 | 0.72 | TP53 (0.40) | — | |
| SCHEMBL5168688 | 0.69 | — | — | |
| SCHEMBL7852949 | 0.67 | — | — | |
| SCHEMBL8179395 | 0.67 | — | — | |
| SCHEMBL16751005 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL27782124 | 0.65 | — | — | |
| SCHEMBL11640072 | 0.65 | — | — | |
| SCHEMBL5200561 | 0.65 | — | — | |
| SCHEMBL11494229 | 0.65 | TP53 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3733660-B1 | N-ALKYL-N-CYANOALKYLBENZAMIDE COMPOUND AND USE THEREOF | JIANGSU FLAG CHEM IND CO LTD (CN) | 2023-08-02 | — | — | EP | disclosed |
| EP-3719011-B1 | PYRAZOLE AMIDE COMPOUND HAVING PESTICIDAL ACTIVITY AND USE THEREOF | JIANGSU FLAG CHEM IND CO LTD (CN) | 2023-03-29 | — | — | EP | disclosed |
| US-11390602-B2 | N-alkyl-N-cyanoalkylbenzamide compound and use thereof | JIANGSU FLAG CHEMICAL INDUSTRY CO., LTD. (CN) | 2022-07-19 | — | — | US | disclosed |
| CN-109988150-B | N-alkyl-N-cyanoalkyl benzamide compounds and application thereof | 江苏中旗科技股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-109988149-B | Pyrazole amide compound with insecticidal activity and application thereof | 江苏中旗科技股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| US-20210009554-A1 | N-ALKYL-N-CYANOALKYLBENZAMIDE COMPOUND AND USE THEREOF | JIANGSU FLAG CHEMICAL INDUSTRY CO., LTD. (CN) | 2021-01-14 | — | — | US | disclosed |
| EP-3733660-A1 | N-ALKYL-N-CYANOALKYLBENZAMIDE COMPOUND AND USE THEREOF | Jiangsu Flag Chemical Industry Co., Ltd. (CN) | 2020-11-04 | — | — | EP | disclosed |
| US-20200329707-A1 | PYRAZOLAMIDE COMPOUND HAVING INSECTICIDAL ACTIVITY AND USE THEREOF | JIANGSU FLAG CHEMICAL INDUSTRY CO., LTD. (CN) | 2020-10-22 | — | — | US | disclosed |
| EP-3719011-A1 | PYRAZOLE AMIDE COMPOUND HAVING PESTICIDAL ACTIVITY AND USE THEREOF | Jiangsu Flag Chemical Industry Co., Ltd. (CN) | 2020-10-07 | — | — | EP | disclosed |
| US-6498133-B2 | 15 TO 60% BY WEIGHT OF AN ACETONITRILE COMPOUND CONTAINING QUATERNARY AMMONIUM GROUP, 20 TO 70% BY WEIGHT OF A SILICON-CONTAINING CARRIER MATERIAL | CLARIANT GMBH (DE) | 2002-12-24 | — | — | US | disclosed |
| US-20020107163-A1 | Particulate bleach activators based on acetonitriles | CLARIANT GMBH | 2002-08-08 | — | — | US | disclosed |
| EP-1207195-A2 | Particulate bleach activators comprising acetonitril | Clariant GmbH (DE) | 2002-05-22 | — | — | EP | disclosed |