Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA known ✓ | P10827 | 1/20 | 0.40 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.40 |
| ▸ | PPARG known ✓ | P37231 | 2/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2234780 | 0.85 | THRA (0.43) | THRATHRBADRB2ADRB1PPARG | |
| SCHEMBL7739699 | 0.83 | THRA (0.42) | THRATHRBADRB2ADRB1PPARG | |
| SCHEMBL5147949 | 0.80 | MEN1 (0.48) | MEN1LMNACYP3A4KMT2A | |
| Sulfuric Acid SCHEMBL11336604 | 0.80 | THRA (0.47) | LTB4RLTB4R2THRATHRBPPARG | |
| SCHEMBL683428 | 0.80 | THRA (0.44) | LTB4RLTB4R2THRATHRBADRB2 | |
| SCHEMBL5435099 | 0.79 | RECQL (0.50) | LTB4RLTB4R2THRATHRBPPARG | |
| SCHEMBL682068 | 0.79 | ALOX5 (0.44) | LTB4RLTB4R2THRATHRBADRB2 | |
| SCHEMBL14443346 | 0.78 | THRA (0.47) | LTB4RLTB4R2THRATHRBADRB2 | |
| SCHEMBL9724546 | 0.78 | CA2 (0.44) | THRATHRBLMNACHRM2CYP3A4 | |
| Sulfuric Acid SCHEMBL1682936 | 0.78 | THRB (0.47) | LTB4RLTB4R2THRATHRBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6496280-B2 | Method for image formation and apparatus for development processing | FUJI PHOTO FILM CO., LTD. (JP) | 2002-12-17 | — | — | US | disclosed |
| US-20010022663-A1 | Method for image formation and apparatus for development processing | FUJIFILM CORPORATION (JP) | 2001-09-20 | — | — | US | disclosed |
| US-6207360-B1 | FIXING-OMITTED DEVELOPMENT PROCESSING, DESILVERING-OMITTED DEVELOPMENT PROCESSING OR BLEACHING-OMITTED DEVELOPMENT PROCESSING | FUJI PHOTO FILM CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| EP-0750225-B1 | Use of hydroxamic acid derivatives for reducing the amount of residual sensitizing dyes after development processing | FUJI PHOTO FILM CO LTD (JP) | 2000-10-04 | — | — | EP | disclosed |
| EP-0750225-A1 | Method for reducing residual sensitizing dyes after development processing | FUJI PHOTO FILM CO., LTD. (JP) | 1996-12-27 | — | — | EP | disclosed |