Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | FABP7 | O15540 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27934324 | 0.99 | KMT2A (0.46) | KMT2ACA1CA2FABP5EPHX2 | |
| Hydrochloric Acid SCHEMBL7876623 | 0.88 | KMT2A (0.49) | KMT2ACA1CA2FABP5EPHX2 | |
| SCHEMBL27905976 | 0.86 | KMT2A (0.50) | KMT2ACA1CA2FABP5EPHX2 | |
| SCHEMBL29701261 | 0.86 | KMT2A (0.50) | KMT2ACA1CA2FABP5EPHX2 | |
| Hydrochloric Acid SCHEMBL5629777 | 0.78 | KMT2A (0.53) | KMT2ACA1CA2FABP5EPHX2 | |
| Hydrochloric Acid SCHEMBL5629771 | 0.78 | KMT2A (0.53) | KMT2ACA1CA2FABP5EPHX2 | |
| SCHEMBL8236718 | 0.78 | KMT2A (0.51) | KMT2ACA1CA2FABP5EPHX2 | |
| Hydrochloric Acid SCHEMBL2174098 | 0.78 | KMT2A (0.55) | KMT2ACA1CA2FABP5EPHX2 | |
| Hydrochloric Acid SCHEMBL7876414 | 0.77 | KMT2A (0.57) | KMT2AFABP5EPHX2FABP7CASP3 | |
| SCHEMBL9500863 | 0.77 | KMT2A (0.50) | KMT2ACA1CA2FABP5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108424376-A | A kind of synthetic method of N- (2-Fmoc- aminoethyls) glycine methyl ester hydrochloride | 苏州凌科特新材料有限公司 | 2018-08-21 | — | — | CN | claimed |
| CN-104211619-B | A kind of synthetic method of N-(2-Fmoc-aminoethyl) glycine methyl ester hydrochloride | 苏州维泰生物技术有限公司 | 2016-08-17 | — | — | CN | claimed |
| CN-104211619-A | Synthetic method for N-(2-Fmoc-aminoethyl)glycine methyl ester hydrochloride | SUZHOU VIVOTIDE BIOTECHNOLOGIES CO LTD | 2014-12-17 | — | — | CN | claimed |
| CN-104151317-A | Fmoc-PNA-G(Bhoc)-OH synthesis method | SUZHOU VIVOTIDE BIOTECHNOLOGIES CO LTD | 2014-11-19 | — | — | CN | claimed |
| CN-103524426-A | Feather weight preparation method of cytosine containing PNA (pentose nucleic acid) monomer | SUZHOU VIVOTIDE BIOTECHNOLOGIES CO LTD | 2014-01-22 | — | — | CN | claimed |
| CN-103524428-A | Feather weight synthesis method of Fmoc-PNA-T-OH | SUZHOU VIVOTIDE BIOTECHNOLOGIES CO LTD | 2014-01-22 | — | — | CN | claimed |
| CN-103145714-A | Feather weight PNA (pentose nucleic acid) synthesis method | SUZHOU VIVOTIDE BIOTECHNOLOGIES CO LTD | 2013-06-12 | — | — | CN | claimed |
| CN-108424376-A | A kind of synthetic method of N- (2-Fmoc- aminoethyls) glycine methyl ester hydrochloride | 苏州凌科特新材料有限公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-108424376-A | A kind of synthetic method of N- (2-Fmoc- aminoethyls) glycine methyl ester hydrochloride | 苏州凌科特新材料有限公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-104211619-B | A kind of synthetic method of N-(2-Fmoc-aminoethyl) glycine methyl ester hydrochloride | 苏州维泰生物技术有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-104211619-B | A kind of synthetic method of N-(2-Fmoc-aminoethyl) glycine methyl ester hydrochloride | 苏州维泰生物技术有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-104211619-A | Synthetic method for N-(2-Fmoc-aminoethyl)glycine methyl ester hydrochloride | SUZHOU VIVOTIDE BIOTECHNOLOGIES CO LTD | 2014-12-17 | — | — | CN | disclosed |
| CN-104211619-A | Synthetic method for N-(2-Fmoc-aminoethyl)glycine methyl ester hydrochloride | SUZHOU VIVOTIDE BIOTECHNOLOGIES CO LTD | 2014-12-17 | — | — | CN | disclosed |
| CN-103524426-A | Feather weight preparation method of cytosine containing PNA (pentose nucleic acid) monomer | SUZHOU VIVOTIDE BIOTECHNOLOGIES CO LTD | 2014-01-22 | — | — | CN | disclosed |
| CN-103524426-A | Feather weight preparation method of cytosine containing PNA (pentose nucleic acid) monomer | SUZHOU VIVOTIDE BIOTECHNOLOGIES CO LTD | 2014-01-22 | — | — | CN | disclosed |
| CN-103524428-A | Feather weight synthesis method of Fmoc-PNA-T-OH | SUZHOU VIVOTIDE BIOTECHNOLOGIES CO LTD | 2014-01-22 | — | — | CN | disclosed |
| CN-103145714-A | Feather weight PNA (pentose nucleic acid) synthesis method | SUZHOU VIVOTIDE BIOTECHNOLOGIES CO LTD | 2013-06-12 | — | — | CN | disclosed |
| CN-103145714-A | Feather weight PNA (pentose nucleic acid) synthesis method | SUZHOU VIVOTIDE BIOTECHNOLOGIES CO LTD | 2013-06-12 | — | — | CN | disclosed |
| US-6316595-B1 | PNA synthesis using a base-labile amino protecting group | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-11-13 | — | — | US | disclosed |
| US-6121418-A | PNA synthesis using a base-labile amino protecting group | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |