Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA known ✓ | P06280 | 1/20 | 0.39 |
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.39 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.35 |
| ▸ | S1PR2 known ✓ | O95136 | 2/20 | 0.30 |
| ▸ | S1PR4 known ✓ | O95977 | 2/20 | 0.30 |
| ▸ | S1PR1 known ✓ | P21453 | 2/20 | 0.30 |
| ▸ | S1PR3 known ✓ | Q99500 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7919819 | 0.97 | CYP2C19 (0.41) | CYP2C19MEN1KMT2AGLAESR1 | |
| Hydrochloric Acid SCHEMBL30706590 | 0.89 | — | — | |
| SCHEMBL791107 | 0.86 | — | — | |
| SCHEMBL1471396 | 0.86 | — | — | |
| SCHEMBL26367204 | 0.83 | CYP2C19 (0.53) | CYP2C19MEN1KMT2AGLACYP1A2 | |
| SCHEMBL3024820 | 0.83 | CYP2C19 (0.53) | CYP2C19MEN1KMT2AGLACYP1A2 | |
| Hydrochloric Acid SCHEMBL8851500 | 0.80 | EPHX1 (0.55) | CYP2C19MEN1KMT2AGLACYP1A2 | |
| SCHEMBL12085580 | 0.80 | CYP2C19 (0.50) | CYP2C19MEN1KMT2AGLACYP1A2 | |
| SCHEMBL7511396 | 0.80 | CYP2C19 (0.56) | CYP2C19MEN1KMT2AGLACYP1A2 | |
| SCHEMBL9971087 | 0.80 | CYP2C19 (0.56) | CYP2C19MEN1KMT2AGLACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240122948-A1 | COMPOSITIONS AND METHODS FOR PREVENTING AND PROTECTING AGAINST DAMAGE IN CELLS AND TISSUES | F3 PLATFORM BIOLOGICS, INC. | 2024-04-18 | — | — | US | claimed |
| EP-4251125-A1 | COMPOSITIONS AND METHODS FOR PREVENTING AND PROTECTING AGAINST DAMAGE IN CELLS AND TISSUES | F3 Platform Biologics, Inc. (US) | 2023-10-04 | — | — | EP | claimed |
| WO-2022115360-A1 | COMPOSITIONS AND METHODS FOR PREVENTING AND PROTECTING AGAINST DAMAGE IN CELLS AND TISSUES | F3 PLATFORM BIOLOGICS, INC. (US) | 2022-06-02 | — | — | WO | claimed |
| CN-109267118-B | Electroplating additive for blind hole filling of circuit board and preparation method thereof | 深圳市正天伟科技有限公司 | 2019-12-13 | — | — | CN | claimed |
| US-20240122948-A1 | COMPOSITIONS AND METHODS FOR PREVENTING AND PROTECTING AGAINST DAMAGE IN CELLS AND TISSUES | F3 PLATFORM BIOLOGICS, INC. | 2024-04-18 | — | — | US | disclosed |
| EP-4251125-A1 | COMPOSITIONS AND METHODS FOR PREVENTING AND PROTECTING AGAINST DAMAGE IN CELLS AND TISSUES | F3 Platform Biologics, Inc. (US) | 2023-10-04 | — | — | EP | disclosed |
| EP-3632419-B1 | METHODS AND COMPOSITIONS FOR PROTECTION OF CELLS AND TISSUES FROM COMPUTED TOMOGRAPHY RADIATION | UNIV CHICAGO (US) | 2022-12-28 | — | — | EP | disclosed |
| WO-2022115360-A1 | COMPOSITIONS AND METHODS FOR PREVENTING AND PROTECTING AGAINST DAMAGE IN CELLS AND TISSUES | F3 PLATFORM BIOLOGICS, INC. (US) | 2022-06-02 | — | — | WO | disclosed |
| US-20210244751-A1 | METHODS AND COMPOSITIONS FOR PROTECTION OF CELLS AND TISSUES FROM COMPUTED TOMOGRAPHY RADIATION | THE UNIVERSITY OF CHICAGO (US) | 2021-08-12 | — | — | US | disclosed |
| US-10987366-B2 | Methods and compositions for protection of cells and tissues from computed tomography radiation | THE UNIVERSITY OF CHICAGO (US) | 2021-04-27 | — | — | US | disclosed |
| EP-3632419-A1 | METHODS AND COMPOSITIONS FOR PROTECTION OF CELLS AND TISSUES FROM COMPUTED TOMOGRAPHY RADIATION | The University of Chicago (US) | 2020-04-08 | — | — | EP | disclosed |
| CN-109267118-B | Electroplating additive for blind hole filling of circuit board and preparation method thereof | 深圳市正天伟科技有限公司 | 2019-12-13 | — | — | CN | disclosed |
| US-5804571-A | ADMINISTERING AN S-OMEGA(OMEGA-AMINOALKYLAMINO)ALKYL DIHYDROGEN PHOSPHOROTHIOATE | U.S. BIOSCIENCE (US) | 1998-09-08 | — | — | US | disclosed |
| EP-0473673-A4 | METHOD FOR PROTECTION FROM AZT SIDE EFFECTS AND TOXICITY | US BIOSCIENCE (US) | 1995-05-17 | — | — | EP | disclosed |
| EP-0391971-B1 | IMPROVING TOXICITY PROFILES IN CHEMOTHERAPY | US BIOSCIENCE (US) | 1994-03-16 | — | — | EP | disclosed |
| EP-0473673-A1 | METHOD FOR PROTECTION FROM AZT SIDE EFFECTS AND TOXICITY | U.S. BIOSCIENCE (US) | 1992-03-11 | — | — | EP | disclosed |
| EP-0391971-A4 | IMPROVING TOXICITY PROFILES IN CHEMOTHERAPY | — | 1991-10-02 | — | — | EP | disclosed |
| WO-1990014007-A1 | METHOD FOR PROTECTION FROM AZT SIDE EFFECTS AND TOXICITY | U.S. BIOSCIENCE (US) | 1990-11-29 | — | — | WO | disclosed |
| EP-0391971-A1 | IMPROVING TOXICITY PROFILES IN CHEMOTHERAPY. | US BIOSCIENCE (US) | 1990-10-17 | — | — | EP | disclosed |
| WO-1989005637-A1 | IMPROVING TOXICITY PROFILES IN CHEMOTHERAPY | U.S. BIOSCIENCE (US) | 1989-06-29 | — | — | WO | disclosed |