Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Isobutanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isobutanol SCHEMBL28999930 | 1.00 | TSHR (0.90) | — | |
| Isobutanol SCHEMBL28999937 | 1.00 | TSHR (0.90) | — | |
| Isobutanol SCHEMBL28276489 | 1.00 | — | — | |
| Isobutanol SCHEMBL28999942 | 1.00 | — | — | |
| Isobutanol SCHEMBL14062107 | 0.95 | — | — | |
| Isobutanol SCHEMBL2784475 | 0.95 | — | — | |
| Isobutanol SCHEMBL11800894 | 0.95 | TSHR (1.00) | — | |
| Isobutanol SCHEMBL969 | 0.95 | — | — | |
| Isobutanol SCHEMBL175952 | 0.95 | TSHR (1.00) | — | |
| Isobutanol SCHEMBL23672280 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321611-B | Preparation method of cefixadine mother nucleus | 湖北凌晟药业有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-112321611-A | Preparation method of cefixadine mother nucleus | 湖北凌晟药业有限公司 | 2021-02-05 | — | — | CN | claimed |
| CN-104860855-B | A kind of preparation method of the methylmercapto butyric acid ester of 2 hydroxyl of the D of high-purity, L 4 | 宁夏紫光天化蛋氨酸有限责任公司 | 2017-06-16 | — | — | CN | claimed |
| CN-104860855-A | Preparation method for high-purity D,L-2-hydroxyl-4-methylthiobutyrate | CHONGQING UNISPLENDOUR CHEM CO | 2015-08-26 | — | — | CN | claimed |
| CN-100494191-C | Method for preparing 3- (imidazole-4-yl) pyridine | DONGYANGGUANG PHARMACEUTICAL C (CN) | 2009-06-03 | — | — | CN | claimed |
| CN-101029044-A | Method for preparing 3- (imidazole-4-yl) pyridine | DONGYANGGUANG PHARMACEUTICAL C (CN) | 2007-09-05 | — | — | CN | claimed |
| EP-4721767-A1 | ANTI-B7-H3 ANTIBODY OR FRAGMENT THEREOF, AND ANTIBODY DRUG CONJUGATE TARGETING B7-H3 | Jiangsu Mabwell Health Pharmaceutical R&D Co., Ltd. (CN) | 2026-04-08 | — | — | EP | disclosed |
| EP-4674851-A1 | PREPARATION METHOD FOR INDOLIZINO[1,2-B]QUINOLINE-10,13-DIONE DERIVATIVE | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2026-01-07 | — | — | EP | disclosed |
| US-20250059201-A1 | CAMPTOTHECIN COMPOUND AND CONJUGATE THEREOF | JIANGSU MABWELL HEALTH PHARMACEUTICAL R&D CO., LTD. (CN) | 2025-02-20 | — | — | US | disclosed |
| WO-2024179564-A1 | PREPARATION METHOD FOR INDOLIZINO[1,2-B]QUINOLINE-10,13-DIONE DERIVATIVE | 江苏恒瑞医药股份有限公司 | 2024-09-06 | — | — | WO | disclosed |
| CN-113563365-B | Preparation method of 7-amino-3-methoxy-4-cephalosporanic acid | 华中药业股份有限公司 | 2024-05-28 | — | — | CN | disclosed |
| US-20220211694-A1 | QUINOLINE DERIVATIVES FOR TREATMENT OF HEAD AND NECK CANCER | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2022-07-07 | — | — | US | disclosed |
| CN-112759602-B | Method for preparing 7-ANCE (carbacephem nucleus) | 湖北凌晟药业有限公司 | 2022-07-01 | — | — | CN | disclosed |
| US-6048677-A | PHOTOGRAPHIC FILMS, SUPPORTS WITH LIGHT SENSITIVE EMULSIONS, RADIATION TRANSPARENT, MAGNETISM LAYER AND SUPERIMPOSING SIDES ON SUPPORTS | EASTMAN KODAK COMPANY (US) | 2000-04-11 | — | — | US | disclosed |
| US-5364824-A | Oxidation | HUNTSMAN SPECIALTY CHEMICALS CORPORATION (US) | 1994-11-15 | — | — | US | disclosed |
| CN-1091998-A | Be used to prepare the catalyst of the promoter elements that contains vanadium-phosphorus oxide and selection of maleic anhydride | MONSANTO CO (US) | 1994-09-14 | — | — | CN | disclosed |
| WO-1994013401-A1 | CATALYSTS FOR THE PRODUCTION OF MALEIC ANHYDRIDE CONTAINING VANADIUM-PHOSPHORUS OXIDE WITH SELECTED PROMOTER ELEMENTS | HUNTSMAN SPECIALTY CHEMICALS CORPORATION (US) | 1994-06-23 | — | — | WO | disclosed |
| EP-0265668-A1 | Process for the preparation of a Diisocyanate | BAYER AG (DE) | 1988-05-04 | — | — | EP | disclosed |
| US-4731093-A | Process for fixing pigments on fiber materials and sheetlike structures | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-03-15 | — | — | US | disclosed |
| EP-0179331-A2 | Process for fixing pigments on fibrous materials and structures having a flat surface | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-04-30 | — | — | EP | disclosed |